Search Results - "Hsiao, Wendy"
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Adaptogenic flower buds exert cancer preventive effects by enhancing the SCFA-producers, strengthening the epithelial tight junction complex and immune responses
Published in Pharmacological research (01-09-2020)“…[Display omitted] Microbiome therapy has attracted a keen interest from both research and business sectors. Our lab has been applying this “second genome”…”
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Discovery of the bioactive peptides secreted by Bifidobacterium using integrated MCX coupled with LC–MS and feature-based molecular networking
Published in Food chemistry (15-06-2021)“…•An integrated approach based on MCX-SPE coupled with LC–MS and FBMN was developed.•25 novel bioactive peptides were quickly characterized from…”
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Thermoreversible Pluronic F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies
Published in International journal of nanomedicine (01-01-2011)“…To develop an in situ gel system comprising liposome-containing paclitaxel (PTX) dispersed within the thermoreversible gel (Pluronic® F127 gel) for controlled…”
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Mushroom polysaccharides from Ganoderma lucidum and Poria cocos reveal prebiotic functions
Published in Journal of functional foods (01-02-2018)“…•Medicinal mushroom polysaccharides on gut microbiota were investigated.•Polysaccharides promoted anti-obesity and anti-inflammatory bacteria.•Polysaccharides…”
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Polarity-Tuning Derivatization-LC-MS Approach for Probing Global Carboxyl-Containing Metabolites in Colorectal Cancer
Published in Analytical chemistry (Washington) (02-10-2018)“…Carboxyl-containing metabolites (CCMs) widely exist in living systems and are the essential components for life. Global characteristics of CCMs in biological…”
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Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum
Published in Gut microbes (01-01-2021)“…Colorectal cancer (CRC) ranks the third most common cancer type in both men and women. Besides the known genetic and epigenetic changes in the gut epithelial…”
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MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
Published in Cell death & disease (28-10-2019)“…MicroRNAs regulate post-transcriptional gene expression and play important roles in multiple cellular processes. In this study, we found that miR-421…”
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Simple and Convenient G-Quadruplex-Based Turn-On Fluorescence Assay for 3′ → 5′ Exonuclease Activity
Published in Analytical chemistry (Washington) (15-01-2011)“…A selective, oligonucleotide-based, label-free, turn-on fluorescence detection method for 3′ → 5′ exonuclease activity has been developed using crystal violet…”
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The Protective Effects of Icariin against the Homocysteine-Induced Neurotoxicity in the Primary Embryonic Cultures of Rat Cortical Neurons
Published in Molecules (Basel, Switzerland) (22-11-2016)“…Icariin, an ingredient in the medicinal herb Maxim ( ), has been considered as a potential therapeutic agent for neurodegenerative diseases such as Alzheimer's…”
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Dietary saponins from four popular herbal tea exert prebiotic-like effects on gut microbiota in C57BL/6 mice
Published in Journal of functional foods (01-08-2015)“…•This study evaluated the impact of herbal tea saponins on gut microbiota.•Herbal tea saponins increased the Bacteriodetes/Firmcutes ratio in mice.•Herbal tea…”
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Traditional Patchouli essential oil modulates the host’s immune responses and gut microbiota and exhibits potent anti-cancer effects in ApcMin /+ mice
Published in Pharmacological research (01-02-2022)“…Patchouli Essential Oil (PEO) has been used as a scent for various healing purposes since the ancient Egyptian period. The primary source of the oil is…”
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Far infrared irradiation suppresses experimental arthritis in rats by down-regulation of genes involved inflammatory response and autoimmunity
Published in Journal of advanced research (01-05-2022)“…[Display omitted] •FIR treatment improved adjuvant arthritis in rats.•FIR exposure inhibited the inflammatory genes expression of synovial tissues in AIA…”
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Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model
Published in Phytomedicine (Stuttgart) (01-02-2020)“…Inulin-type fructo-oligosaccharides (FOSs) purified from Morinda officinalis How., an effective oral antidepressant for mild to moderate depression, have a…”
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Patchouli Essential Oil and Its Derived Compounds Revealed Prebiotic-Like Effects in C57BL/6J Mice
Published in Frontiers in pharmacology (17-10-2019)“…Pogostemon cablin (Blanco) Benth (PC) is a Chinese medicinal plant traditionally used for the treatment of gastrointestinal symptoms. To investigate the…”
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The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity
Published in Frontiers in pharmacology (08-01-2018)“…Rheumatoid arthritis synovial fibroblasts (RASFs) are fundamental effector cells in RA driving the joint inflammation and deformities. Celastrol is a natural…”
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Far infrared radiation induces changes in gut microbiota and activates GPCRs in mice
Published in Journal of advanced research (01-03-2020)“…[Display omitted] •Transient exposure of FIR induced compositional and temporal changes in gut microbiota of mice.•FIR exposure stimulated growth of the gut…”
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Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties
Published in Frontiers in pharmacology (29-09-2023)“…Introduction: Pathological angiogenesis, the abnormal or excessive generation of blood vessels, plays an important role in many diseases including cancer,…”
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The role of traditional Chinese herbal medicines in cancer therapy--from TCM theory to mechanistic insights
Published in Planta medica (01-08-2010)“…Traditional Chinese medicine-based herbal medicines have gained increasing acceptance worldwide in recent years and are being pursued by pharmaceutical…”
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Prognostic significance of tumor poliovirus receptor and CTLA4 expression in patients with surgically resected non-small-cell lung cancer
Published in Journal of cancer research and clinical oncology (01-06-2020)“…Introduction Poliovirus receptor (PVR) is a tumor promoter and a regulatory checkpoint that enhances immunosuppression. We investigated PVR expression by…”
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