Search Results - "Hsiang-fu Kung"
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MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression
Published in PloS one (22-04-2011)“…MicroRNAs (miRNAs) are endogenous, small noncoding RNAs that play important roles in various cellular functions and tumor development. Recent studies have…”
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2
High‐mobility group box 1 released by autophagic cancer‐associated fibroblasts maintains the stemness of luminal breast cancer cells
Published in The Journal of pathology (01-11-2017)“…Cancer stem cells/cancer‐initiating cells (CICs) and their microenvironmental niche play a vital role in malignant tumour recurrence and metastasis…”
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3
Ursolic acid promotes cancer cell death by inducing Atg5‐dependent autophagy
Published in International journal of cancer (15-12-2013)“…Ursolic acid (UA) has been reported to possess anticancer activities. Although some of the anticancer activities of UA have been explained by its…”
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4
Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling
Published in Journal of hepatology (01-10-2015)“…Graphical abstract…”
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5
MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2
Published in Cancer research (Chicago, Ill.) (2011)“…Several microRNAs (miRNA) have been implicated in nasopharyngeal carcinoma (NPC), a highly invasive and metastatic cancer that is widely prevalent in southern…”
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6
Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance
Published in Science translational medicine (30-05-2018)“…Glioblastoma (GBM) is the most lethal primary brain tumor and is highly resistant to current treatments. GBM harbors glioma stem cells (GSCs) that not only…”
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7
Suppression of tumorigenicity by MicroRNA-138 through inhibition of EZH2-CDK4/6-pRb-E2F1 signal loop in glioblastoma multiforme
Published in Biochimica et biophysica acta (01-10-2013)“…Deregulation of microRNAs (miRNAs) is implicated in tumor progression. We attempt to indentify the tumor suppressive miRNA not only down-regulated in…”
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Analysis of MiR-195 and MiR-497 Expression, Regulation and Role in Breast Cancer
Published in Clinical cancer research (01-04-2011)“…To investigate expression, regulation, potential role and targets of miR-195 and miR-497 in breast cancer. The expression patterns of miR-195 and miR-497 were…”
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Primate‐specific microRNA‐637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling
Published in Hepatology (Baltimore, Md.) (01-12-2011)“…MiR‐637 (microRNA‐637) is a primate‐specific miRNA belonging to the small noncoding RNA family, which represses gene regulation at the post‐transcriptional…”
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10
Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer
Published in Gut (01-04-2015)“…Characterisation of colorectal cancer (CRC) genomes by next-generation sequencing has led to the discovery of novel recurrently mutated genes. Nevertheless,…”
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11
Transcriptional and epigenetic regulation of human microRNAs
Published in Cancer letters (30-04-2013)“…Highlights ► MiRNAs are dysregulated in many human diseases, in particular cancers. ► Transcriptional and epigenetic regulations play major roles in miRNA…”
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12
Revisit complexation between DNA and polyethylenimine — Effect of uncomplexed chains free in the solution mixture on gene transfection
Published in Journal of controlled release (10-10-2011)“…Our revisit of the complexation between anionic DNA and cationic polyethylenimine (PEI) in both water and phosphate buffered saline (PBS) by using a…”
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13
Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma
Published in PloS one (03-04-2013)“…It has been suggested that autophagy-related Beclin 1 plays a critical role in the regulation of tumor development and/or progression, but its prognostic…”
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14
Enterovirus 71 Disrupts Interferon Signaling by Reducing the Level of Interferon Receptor 1
Published in Journal of Virology (01-04-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix
Published in Molecular biology of the cell (01-11-2011)“…Bone development is dynamically regulated by homeostasis, in which a balance between adipocytes and osteoblasts is maintained. Disruption of this…”
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16
Stanniocalcin-1 augments stem-like traits of glioblastoma cells through binding and activating NOTCH1
Published in Cancer letters (01-03-2018)“…Glioblastoma (GBM) is a fatal tumor and comprises heterogeneous cells in which a subpopulation with stem cell-like properties is included. Cancer cells with…”
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17
Systemic delivery of microRNA-101 potently inhibits hepatocellular carcinoma in vivo by repressing multiple targets
Published in PLoS genetics (01-02-2015)“…Targeted therapy based on adjustment of microRNA (miRNA)s activity takes great promise due to the ability of these small RNAs to modulate cellular behavior…”
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18
miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion
Published in Biochemical and biophysical research communications (01-01-2010)“…Nasopharyngeal carcinoma (NPC), a highly metastatic and invasive malignant tumor originating from the nasopharynx, is widely prevalent in Southeast Asia, the…”
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19
Loss of Brain-enriched miR-124 MicroRNA Enhances Stem-like Traits and Invasiveness of Glioma Cells
Published in The Journal of biological chemistry (23-03-2012)“…miR-124 is a brain-enriched microRNA that plays a crucial role in neural development and has been shown to be down-regulated in glioma and medulloblastoma,…”
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20
Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer
Published in Molecular cancer (28-01-2011)“…B-lymphoma Moloney murine leukemia virus insertion region-1 (Bmi-1) acts as an oncogene in various tumors, and its overexpression correlates with a poor…”
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