Search Results - "Hsia, C C"
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Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
Published in Science (American Association for the Advancement of Science) (23-11-2018)“…During tissue repair, myofibroblasts produce extracellular matrix (ECM) molecules for tissue resilience and strength. Altered ECM deposition can lead to tissue…”
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Single cell transcriptomic landscape of diabetic foot ulcers
Published in Nature communications (10-01-2022)“…Diabetic foot ulceration (DFU) is a devastating complication of diabetes whose pathogenesis remains incompletely understood. Here, we profile 174,962 single…”
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Comparative analysis of the mechanical signals in lung development and compensatory growth
Published in Cell and tissue research (01-03-2017)“…This review compares the manner in which physical stress imposed on the parenchyma, vasculature and thorax and the thoraco-pulmonary interactions, drive both…”
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Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough
Published in Cell (16-04-2020)“…Pulmonary tuberculosis, a disease caused by Mycobacterium tuberculosis (Mtb), manifests with a persistent cough as both a primary symptom and mechanism of…”
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The potential and limitations of induced pluripotent stem cells to achieve wound healing
Published in Stem cell research & therapy (12-03-2019)“…Wound healing is the physiologic response to a disruption in normal skin architecture and requires both spatial and temporal coordination of multiple cell…”
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Reversible modulation of myofibroblast differentiation in adipose-derived mesenchymal stem cells
Published in PloS one (23-01-2014)“…Unregulated activity of myofibroblasts, highly contractile cells that deposit abundant extracellular matrix (ECM), leads to fibrosis. To study the modulation…”
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The role of ciliary trafficking in Hedgehog receptor signaling
Published in Science signaling (02-06-2015)“…Defects in the biogenesis of or transport through primary cilia affect Hedgehog protein signaling, and many Hedgehog pathway components traffic through or…”
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Nano-Therapeutics for the Lung: State-of-the-Art and Future Perspectives
Published in Current pharmaceutical design (01-01-2015)“…Inhalation of aerosolized compounds is a popular, non-invasive route for the targeted delivery of therapeutic molecules to the lung. Various types of…”
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The Efficacy and Safety of Fostamatinib in Elderly Patients with Immune Thrombocytopenia: A Single-Center, Real-World Case Series
Published in Advances in hematology (03-11-2022)“…Fostamatinib is a small molecule spleen tyrosine kinase (Syk) inhibitor that was approved for the treatment of adult patients with immune thrombocytopenia…”
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Lung protection by inhalation of exogenous solubilized extracellular matrix
Published in PloS one (02-02-2017)“…Decellularized extracellular matrix (ECM) contains complex tissue-specific components that work in concert to promote tissue repair and constructive remodeling…”
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Characterization of Mg,Al-hydrotalcite conversion film on Mg alloy and Cl− and CO32- anion-exchangeability of the film in a corrosive environment
Published in Scripta materialia (01-06-2007)Get full text
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Early MRI measures independently predict 1-year and 2-year radiographic progression in rheumatoid arthritis: secondary analysis from a large clinical trial
Published in Annals of the rheumatic diseases (01-11-2014)“…To determine if early MRI measures predict X-ray progression at 1 and 2 years in a large RA trial cohort. This study included 256 methotrexate (MTX)-naïve RA…”
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Incidence and Risk Factors for Tuberculosis After Liver Transplantation in an Endemic Area: A Nationwide Population‐Based Matched Cohort Study
Published in American journal of transplantation (01-08-2015)“…Morbidity and mortality from tuberculosis (TB) are high in Taiwan. We conducted a nationwide population‐based matched cohort study using data retrieved from…”
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Pooled safety results across phase 3 randomized trials of intravenous golimumab in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis
Published in Arthritis research & therapy (21-03-2022)“…Intravenous (IV) golimumab, a TNFi, is approved for treating rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). We analyzed…”
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Guselkumab demonstrated an independent treatment effect in reducing fatigue after adjustment for clinical response-results from two phase 3 clinical trials of 1120 patients with active psoriatic arthritis
Published in Arthritis research & therapy (14-07-2021)“…The interleukin-23p19-subunit inhibitor guselkumab effectively treats signs and symptoms of psoriatic arthritis (PsA). We evaluated the effect of guselkumab on…”
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How much is there really? Why stereology is essential in lung morphometry
Published in Journal of applied physiology (1985) (01-01-2007)“…1 Institute of Anatomy, University of Bern, Bern, Switzerland; and 2 Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas,…”
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Hedgehog mediated degradation of Ihog adhesion proteins modulates cell segregation in Drosophila wing imaginal discs
Published in Nature communications (02-11-2017)“…The Drosophila Hedgehog receptor functions to regulate the essential downstream pathway component, Smoothened, and to limit the range of signaling by…”
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Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor α inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial
Published in The Lancet (British edition) (18-07-2009)“…Summary Background Tumour necrosis factor α (TNFα) inhibitors are frequently used to treat rheumatoid arthritis, but whether use of a different TNFα inhibitor…”
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Randomized, phase III trial of figitumumab in combination with erlotinib versus erlotinib alone in patients with nonadenocarcinoma nonsmall-cell lung cancer
Published in Annals of oncology (01-03-2015)“…The addition of figitumumab to erlotinib did not improve outcomes in patients with advanced, pretreated, nonadenocarcinoma NSCLC. Figitumumab (CP-751,871) is a…”
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