Search Results - "Hsi, Linda"
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Adeno-associated virus-9 reverses delayed gastric emptying of solids in diabetic mice
Published in Neurogastroenterology and motility (01-11-2023)“…Gastroparesis is defined by delayed gastric emptying (GE) without obstruction. Studies suggest targeting heme oxygenase-1 (HO1) may ameliorate diabetic…”
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2
Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites
Published in PloS one (22-12-2011)“…3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) inhibitors, commonly known as statins, may possess cancer preventive and therapeutic properties…”
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3
From macrophage interleukin-13 receptor to foam cell formation: mechanisms for αMβ2 integrin interference
Published in The Journal of biological chemistry (25-01-2013)“…IL-13 is a potent stimulator of alternative monocyte/macrophage activation. During alternative activation, the expression of several proteins is induced…”
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4
Silencing IL-13Rα2 promotes glioblastoma cell death via endogenous signaling
Published in Molecular cancer therapeutics (01-07-2011)“…Glioblastoma multiforme (GBM) is one of the most lethal forms of cancer, with a survival rate of only 13% to 27% within 2 years of diagnosis despite optimal…”
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5
Protocol for isolating immune cells from human gastric muscularis propria for single-cell analysis
Published in STAR protocols (20-09-2024)“…Understanding the diversity of gastrointestinal (GI) immune cells, especially in the muscularis propria, is crucial for understanding their role in the…”
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6
Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity
Published in The Journal of biological chemistry (21-02-2003)“…Troglitazone (TGZ) is a peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand that has pro-apoptotic activity in human colon cancer. Although…”
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7
Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma
Published in The Journal of biological chemistry (25-10-2002)“…Human prostate tumors have elevated levels of 15-lipoxygenase-1 (15-LOX-1) and data suggest that 15-LOX-1 may play a role in the development of prostate…”
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8
The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells
Published in Cancer research (Chicago, Ill.) (01-12-2004)“…Histone deacetylases (HDACs) mediate changes in nucleosome conformation and are important in the regulation of gene expression. HDACs are involved in cell…”
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9
The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells
Published in Molecular cancer therapeutics (01-11-2005)“…DNA methylation by DNA methyltransferases in CpG-rich promoter regions of genes is a well-described component of epigenetic silencing in human cells…”
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10
Introduction of full-length APC modulates cyclooxygenase-2 expression in HT-29 human colorectal carcinoma cells at the translational level
Published in Carcinogenesis (New York) (01-11-1999)“…Mutation of the adenomatous polyposis coli (APC) gene is associated with the earliest stages of colorectal tumorigenesis and appears to be responsible for the…”
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11
Histidine 386 and Its Role in Cyclooxygenase and Peroxidase Catalysis by Prostaglandin-endoperoxide H Synthases
Published in The Journal of biological chemistry (14-11-2003)“…Prostaglandin-endoperoxide H synthases (PGHSs) have a cyclooxygenase that forms prostaglandin (PG) G2 from arachidonic acid (AA) plus oxygen and a peroxidase…”
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12
1265 REGIONAL CHANGES IN CALCIUM WAVES GENERATED BY INTERSTITIAL CELLS OF CAJAL IN A MOUSE MODEL OF DIABETIC GASTROPARESIS
Published in Gastroenterology (New York, N.Y. 1943) (18-05-2024)Get full text
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13
Su1212 THE ELECTROGENIC SODIUM/BICARBONATE COTRANSPORTER SLC4A4 IS REQUIRED FOR SLOW WAVE (SW) GENERATION BY INTERSTITIAL CELLS OF CAJAL (ICC) BUT IS NOT SOLELY RESPONSIBLE FOR THE EFFECTS OF BICARBONATE ON SW ACTIVITY
Published in Gastroenterology (New York, N.Y. 1943) (18-05-2024)Get full text
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656 CHANGES TO GASTRIC TISSUE RESIDENT MUSCULARIS MACROPHAGES PHENOTYPE FOLLOWING THE ONSET OF DIABETES
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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15
Nitric Oxide Trapping of the Tyrosyl Radical of Prostaglandin H Synthase-2 Leads to Tyrosine Iminoxyl Radical and Nitrotyrosine Formation
Published in The Journal of biological chemistry (04-07-1997)“…The determination of protein nitrotyrosine content has become a frequently used technique for the detection of oxidative tissue damage. Protein nitration has…”
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Arachidonic and Linoleic Acid Metabolism in Mouse Intestinal Tissue: Evidence for Novel Lipoxygenase Activity
Published in Archives of biochemistry and biophysics (01-02-2002)“…Previous studies in our laboratory revealed a high expression of 15-lipoxygenase-1 in human colorectal carcinomas, suggesting the importance of lipoxygenase in…”
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669 GASTROINTESTINAL DISEASE-RELATED SINGLE-NUCLEOTIDE VARIANTS (SNVS) COLOCALIZE WITH CIS-REGULATORY ELEMENTS (CRES) OF THE ELECTRICAL SLOW WAVE (SW)-ASSOCIATED GENE SLC4A4 IN A HUMAN MODEL OF PACEMAKER INTERSTITIAL CELLS OF CAJAL (ICC)
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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18
Anti-β2GPI antibodies stimulate endothelial cell microparticle release via a nonmuscle myosin II motor protein-dependent pathway
Published in Blood (28-11-2013)“…The antiphospholipid syndrome is characterized by thrombosis and recurrent fetal loss in patients with antiphospholipid antibodies (APLAs). Most pathogenic…”
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Lack of Cyclooxygenase-2 Activity in HT-29 Human Colorectal Carcinoma Cells
Published in Experimental cell research (01-05-2000)“…Induction of cyclooxygenase-2 (COX-2) is an early event in the sequence of polyp formation to colon carcinogenesis. COX-2 is at elevated levels in human…”
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Su1960 DYNAMICS OF CIRCULATING MONOCYTES IN A MOUSE MODEL OF DIABETIC GASTROPARESIS
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2023)Get full text
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