Search Results - "Hryciw, DH"

The role of maternal nutrition, metabolic function and the placenta in developmental programming of renal dysfunction by Richter, VFI, Briffa, JF, Moritz, KM, Wlodek, ME, Hryciw, DH

“…Summary The intrauterine environment is critical for the development of the foetus. Barker and colleagues were the first to identify that adverse perturbations…”
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Diet induced obesity in rats reduces NHE 3 and Na + /K + ‐ ATP ase expression in the kidney by Briffa, JF, Grinfeld, E, Jenkin, KA, Mathai, ML, Poronnik, P, McAinch, AJ, Hryciw, DH

“…The consumption of a high fat diet ( HFD ) is associated with proteinuria and altered sodium handling and excretion, which can lead to kidney disease. In the…”
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Diet induced obesity in rats reduces NHE3 and Na+/K+-ATPase expression in the kidney by Briffa, JF, Grinfeld, E, Jenkin, KA, Mathai, ML, Poronnik, P, McAinch, AJ, Hryciw, DH

“…Summary The consumption of a high fat diet (HFD) is associated with proteinuria and altered sodium handling and excretion, which can lead to kidney disease. In…”
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Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds. Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5 by Hryciw, Deanne H, Ekberg, Jenny, Ferguson, Charles, Lee, Aven, Wang, Dongsheng, Parton, Robert G, Pollock, Carol A, Yun, Chris C, Poronnik, Philip

“…The constitutive reuptake of albumin from the glomerular filtrate by receptor-mediated endocytosis is a key function of the renal proximal tubules. Both the…”
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Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells by Hryciw, Deanne H, Ekberg, Jenny, Lee, Aven, Lensink, Ingrid L, Kumar, Sharad, Guggino, William B, Cook, David I, Pollock, Carol A, Poronnik, Philip

“…Constitutive albumin uptake by the proximal tubule is achieved by a receptor-mediated process in which the Cl(-) channel, ClC-5, plays an obligate role. Here…”
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Cofilin Interacts with ClC-5 and Regulates Albumin Uptake in Proximal Tubule Cell Lines by Hryciw, Deanne H., Wang, Yinghong, Devuyst, Olivier, Pollock, Carol A., Poronnik, Philip, Guggino, William B.

“…Receptor-mediated endocytosis is a constitutive high capacity pathway for the reabsorption of proteins from the glomerular filtrate by the renal proximal…”
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A yellow fluorescent protein-based assay for high-throughput screening of glycine and GABA A receptor chloride channels by Kruger, Wade, Gilbert, Daniel, Hawthorne, Rebecca, Hryciw, Deanne H., Frings, Stephan, Poronnik, Philip, Lynch, Joseph W.

“…There is a significant clinical need to identify novel ligands with high selectivity and potency for GABA A, GABA C and glycine receptor Cl − channels. Two…”
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ClC-5: role in endocytosis in the proximal tubule by Wang, Yinghong, Cai, Hui, Cebotaru, Liudmila, Hryciw, Deanne H, Weinman, Edward J, Donowitz, Mark, Guggino, Sandra E, Guggino, William B

“…The proper functioning of the Cl(-) channel, ClC-5, is essential for the uptake of low molecular mass proteins through receptor-mediated endocytosis in the…”
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PKC-alpha-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells by Hryciw, Deanne H, Pollock, Carol A, Poronnik, Philip

“…One key role of the renal proximal tubule is the reabsorption of proteins from the glomerular filtrate by constitutive receptor-mediated endocytosis. In the…”
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MOLECULAR CHANGES IN PROXIMAL TUBULE FUNCTION IN DIABETES MELLITUS by Hryciw, Deanne H, Lee, Erwin M, Pollock, Carol A, Poronnik, Philip

“…Summary 1. Diabetic kidney disease is initially associated with hypertension and increased urinary albumin excretion. The hypertension is mediated by enhanced…”
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Postnatal developmental expression of the PDZ scaffolds Na+ -H+ exchanger regulatory factors 1 and 2 in the rat cochlea by Kanjhan, Refik, Hryciw, Deanne H, Yun, C Chris, Bellingham, Mark C, Poronnik, Philip

“…Sensory transduction in the mammalian cochlea requires the maintenance of specialized fluid compartments with distinct ionic compositions. This is achieved by…”
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Cystic Fibrosis Transmembrane Conductance Regulator And The Outwardly Rectifying Chloride Channel: A Relationship Between Two Chloride Channels Expressed In Epithelial Cells by Hryciw, Deanne H, Guggino, William B

“…SUMMARY 1. Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) result in the primary defect observed in patients with cystic fibrosis…”
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Relevance of the D13 Region to the Function of the Skeletal Muscle Chloride Channel, ClC-1 by Hryciw, D H, Rychkov, G Y, Hughes, B P, Bretag, A H

“…Although hydropathy analysis of the skeletal muscle chloride channel protein, ClC-1, initially predicted 13 potential membrane spanning domains (D1 to D13),…”
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