Search Results - "Hrvacic, Boska"

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis by Desroy, Nicolas, Housseman, Christopher, Bock, Xavier, Joncour, Agnès, Bienvenu, Natacha, Cherel, Laëtitia, Labeguere, Virginie, Rondet, Emilie, Peixoto, Christophe, Grassot, Jean-Marie, Picolet, Olivier, Annoot, Denis, Triballeau, Nicolas, Monjardet, Alain, Wakselman, Emanuelle, Roncoroni, Veronique, Le Tallec, Sandrine, Blanque, Roland, Cottereaux, Celine, Vandervoort, Nele, Christophe, Thierry, Mollat, Patrick, Lamers, Marieke, Auberval, Marielle, Hrvacic, Boska, Ralic, Jovica, Oste, Line, van der Aar, Ellen, Brys, Reginald, Heckmann, Bertrand

“…Autotaxin is a circulating enzyme with a major role in the production of lysophosphatic acid (LPA) species in blood. A role for the autotaxin/LPA axis has been…”
Get full text

Azithromycin inhibits macrophage interleukin-1β production through inhibition of activator protein-1 in lipopolysaccharide-induced murine pulmonary neutrophilia by Bosnar, Martina, Čužić, Snježana, Bošnjak, Berislav, Nujić, Krunoslav, Ergović, Gabrijela, Marjanović, Nikola, Pašalić, Ivanka, Hrvačić, Boška, Polančec, Denis, Glojnarić, Ines, Haber, Vesna Eraković

“…Macrolide antibiotics, including azithromycin, also possess anti-inflammatory properties. However, the molecular mechanism(s) of activity as well as the target…”
Get full text

Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma by HRVACIE, Boska, BOSNJAK, Berislav, TUDJA, Marijan, MESIE, Milan, MERCEP, Mladen

“…We have assessed the use of an ultrasonic nebulization system (UNS), composed of ultrasonic nebulizer and diffusion dryer filled with charcoal, for the…”
Get full text

Synthesis and Anti-inflammatory Activity of Novel Furochromenes by Elenkov, Ivaylo Jivkov, Hrvacic, Boska, Markovic, Stribor, Mesic, Milan, Klonkay, Andreja Cempuh, Lerman, Lidija, Sucic, Anita Filipovic, Vujasinovic, Ines, Bosnjak, Berislav, Brajsa, Karmen, Ziher, Dinko, Hulita, Nada Kosutic, Malnar, Ivica

“…A series of variously substituted furochromenes, hemiacetals 2, acetals 3, and rearranged compounds 4, were synthesized from variously substituted…”
Get full text

Porphyrins as new endogenous anti-inflammatory agents by Jelić, Dubravko, Tatić, Iva, Trzun, Marija, Hrvačić, Boška, Brajša, Karmen, Verbanac, Donatella, Tomašković, Marija, Čulić, Ognjen, Antolović, Roberto, Glojnarić, Ines, Weygand-Đurašević, Ivana, Vladimir-Knežević, Sanda, Mildner, Boris

“…A series of porphyrins, tetrapyrrole natural organic compounds, are evaluated here as endogenous anti-inflammatory agents. They directly inhibit the activity…”
Get full text

Immunomodulatory effects of azithromycin on serum amyloid A production in lipopolysaccharide-induced endotoxemia in mice by Tkalčević, Vanesa Ivetić, Hrvačić, Boška, Pašalić, Ivanka, Haber, Vesna Eraković, Glojnarić, Ines

Get full text

Macrolactonolides: A novel class of anti-inflammatory compounds by Tomašković, Linda, Komac, Marijana, Makaruha Stegić, Oresta, Munić, Vesna, Ralić, Jovica, Stanić, Barbara, Banjanac, Mihailo, Marković, Stribor, Hrvačić, Boška, Čipčić Paljetak, Hana, Padovan, Jasna, Glojnarić, Ines, Eraković Haber, Vesna, Mesić, Milan, Merćep, Mladen

“…A new concept in design of safe glucocorticoid therapy was introduced by conjugating potent glucocorticoid steroids with macrolides (macrolactonolides). These…”
Get full text

The anti-inflammatory activity of clarithromycin inhibits TNFα production and prolongs survival following lipopolysaccharide administration in mice by Tkalčević, Vanesa Ivetić, Bošnjak, Berislav, Pašalić, Ivanka, Hrvačić, Boška, Šitum, Kristina, Kramarić, Miroslava Dominis, Glojnarić, Ines, Haber, Vesna Eraković

Get full text

Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice by Ivetić Tkalčević, Vanesa, Bošnjak, Berislav, Hrvačić, Boška, Bosnar, Martina, Marjanović, Nikola, Ferenčić, Željko, Šitum, Kristina, Čulić, Ognjen, Parnham, Michael J., Eraković, Vesna

“…Macrolide antibacterials inhibit the production of various cytokines and the migration of inflammatory cells. These anti-inflammatory actions of macrolides may…”
Get full text

Differing effects of two iron compounds on experimental arthritis, TNF-α levels and immune response in mice by POLJAK-BLAZI, Marija, HRVACIC, Boska, ZUPANOVIC, Zeljko, HADZIJA, Mirko, STANIC, Barbara, POLANCEC, Denis

“…The effects of ferric-sorbitol-citrate and ferric-citrate on the severity of experimental arthritis, TNF-α secretion and the immune status were examined in…”
Get full text

Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model by Hafner, Michael, Paukner, Susanne, Wicha, Wolfgang W, Hrvačić, Boška, Cedilak, Matea, Faraho, Ivan, Gelone, Steven P

“…Several antibiotics demonstrate both antibacterial and anti-inflammatory/immunomodulatory activities and are used to treat inflammatory pulmonary disorders…”
Get full text

Intranasal challenge with increasing ovalbumin doses differently affects airway hyperresponsiveness and inflammatory cell accumulation in mouse model of asthma by Bosnjak, Berislav, Ivetić Tkalcević, Vanesa, Durić, Koraljka, Belamarić, Daniela, Cuzić, Snjezana, Ferencić, Zeljko, Brajsa, Karmen, Glojnarić, Ines, Antolović, Roberto, Hrvacić, Boska

“…Objective To investigate whether challenge with increasing allergen doses could differently affect allergen-induced airway hyperresponsiveness (AHR) and…”
Get full text

Claudins: Beyond Tight Junctions in Human IBD and Murine Models by Čužić, Snježana, Antolić, Maja, Ognjenović, Anja, Stupin-Polančec, Darija, Petrinić Grba, Adriana, Hrvačić, Boška, Dominis Kramarić, Miroslava, Musladin, Sanja, Požgaj, Lidija, Zlatar, Ivo, Polančec, Denis, Aralica, Gorana, Banić, Marko, Urek, Marija, Mijandrušić Sinčić, Brankica, Čubranić, Aleksandar, Glojnarić, Ines, Bosnar, Martina, Eraković Haber, Vesna

“…Claudins are transmembrane proteins constituting one of three tight junction protein families. In patients with inflammatory bowel disease (IBD), disease…”
Get full text

Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories by Ivetic Tkalcevic, Vanesa, Hrvacic, Boska, Bosnar, Martina, Cuzic, Snjezana, Bosnjak, Berislav, Erakovic Haber, Vesna, Glojnaric, Ines

“…The murine model of cantharidin-induced ear inflammation was profiled in detail for its alignment with the human model and to explore the mechanism of…”
Get full text

Clarithromycin suppresses airway hyperresponsiveness and inflammation in mouse models of asthma by Hrvačić, Boška, Bošnjak, Berislav, Bosnar, Martina, Ferenčić, Željko, Glojnarić, Ines, Haber, Vesna Eraković

“…Macrolide antibiotics, a class of potent antimicrobials, also possess immunomodulatory/anti-inflammatory properties. These properties are considered…”
Get full text

N′-Substituted-2′-O,3′-N-carbonimidoyl Bridged Macrolides: Novel Anti-inflammatory Macrolides without Antimicrobial Activity by Bosnar, Martina, Kragol, Goran, Koštrun, Sanja, Vujasinović, Ines, Bošnjak, Berislav, Bencetić Mihaljević, Vlatka, Marušić Ištuk, Zorica, Kapić, Samra, Hrvačić, Boška, Brajša, Karmen, Tavčar, Branka, Jelić, Dubravko, Glojnarić, Ines, Verbanac, Donatella, Čulić, Ognjen, Padovan, Jasna, Alihodžić, Sulejman, Eraković Haber, Vesna, Spaventi, Radan

“…Macrolide antibiotics, like erythromycin, clarithromycin, and azithromycin, possess anti-inflammatory properties. These properties are considered fundamental…”
Get full text

Relative potencies of three glucocorticoids to induce hypoplasia of the physis and concomitant biochemical alterations in the rat by Hrvačić, Boška, Šitum, Kristina, Đurić, Koraljka, Bošnjak, Berislav, Ferenčić, Željko, Brajša, Karmen, Marković, Stribor, Glojnarić, Ines

“…Although inhaled glucocorticoids are known to have systemic effects on bone metabolism, there is little comparative information on their relative potencies…”
Get full text

Discovery of 2‑[[2-Ethyl-6-[4-[2-(3-hydroxy­azetidin-1-yl)-2-oxoethyl]­piperazin-1-yl]-8-methyl­imidazo[1,2‑a]pyridin-3-yl]­methylamino]-4-(4-fluorophenyl)­thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis by Desroy, Nicolas, Housseman, Christopher, Bock, Xavier, Joncour, Agnès, Bienvenu, Natacha, Cherel, Laëtitia, Labeguere, Virginie, Rondet, Emilie, Peixoto, Christophe, Grassot, Jean-Marie, Picolet, Olivier, Annoot, Denis, Triballeau, Nicolas, Monjardet, Alain, Wakselman, Emanuelle, Roncoroni, Veronique, Le Tallec, Sandrine, Blanque, Roland, Cottereaux, Celine, Vandervoort, Nele, Christophe, Thierry, Mollat, Patrick, Lamers, Marieke, Auberval, Marielle, Hrvacic, Boska, Ralic, Jovica, Oste, Line, van der Aar, Ellen, Brys, Reginald, Heckmann, Bertrand

“…Autotaxin is a circulating enzyme with a major role in the production of lysophosphatic acid (LPA) species in blood. A role for the autotaxin/LPA axis has been…”
Get full text

Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte-macrophage colony-stimulating factor and interleukin-1beta by Bosnar, Martina, Bosnjak, Berislav, Cuzic, Snjezana, Hrvacic, Boska, Marjanovic, Nikola, Glojnaric, Ines, Culic, Ognjen, Parnham, Michael J, Erakovic Haber, Vesna

“…Macrolide antibiotics possess immunomodulatory/anti-inflammatory properties. These properties are considered fundamental for the efficacy of macrolide…”
Get more information

The anti-inflammatory activity of clarithromycin inhibits TNFalpha production and prolongs survival following lipopolysaccharide administration in mice by Tkalcević, Vanesa Ivetić, Bosnjak, Berislav, Pasalić, Ivanka, Hrvacić, Boska, Situm, Kristina, Kramarić, Miroslava Dominis, Glojnarić, Ines, Eraković Haber, Vesna

Get full text