Search Results - "Hrouzek, Pavel"
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Hunting the eagle killer: A cyanobacterial neurotoxin causes vacuolar myelinopathy
Published in Science (American Association for the Advancement of Science) (26-03-2021)“…Vacuolar myelinopathy is a fatal neurological disease that was initially discovered during a mysterious mass mortality of bald eagles in Arkansas in the United…”
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Structure elucidation of the novel carotenoid gemmatoxanthin from the photosynthetic complex of Gemmatimonas phototrophica AP64
Published in Scientific reports (05-08-2021)“…Gemmatimonas phototrophica AP64 is the first phototrophic representative of the bacterial phylum Gemmatimonadetes . The cells contain photosynthetic complexes…”
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A hybrid non-ribosomal peptide/polyketide synthetase containing fatty-acyl ligase (FAAL) synthesizes the β-amino fatty acid lipopeptides puwainaphycins in the Cyanobacterium Cylindrospermum alatosporum
Published in PloS one (04-11-2014)“…A putative operon encoding the biosynthetic pathway for the cytotoxic cyanobacterial lipopeptides puwainphycins was identified in Cylindrospermum alatosporum…”
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The Primitive Thylakoid-Less Cyanobacterium Gloeobacter Is a Common Rock-Dwelling Organism
Published in PloS one (18-06-2013)“…Cyanobacteria are an ancient group of photosynthetic prokaryotes, which are significant in biogeochemical cycles. The most primitive among living…”
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High-performance countercurrent chromatography for lutein production from a chlorophyll-deficient strain of the microalgae Parachlorella kessleri HY1
Published in Journal of applied phycology (01-08-2021)“…Green microalgae are a recognized lutein source; however, processing for lutein production requires additional operations such as extraction and…”
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Comparison of various approaches to detect algal culture contamination: a case study of Chlorella sp. contamination in a Phaeodactylum tricornutum culture
Published in Applied microbiology and biotechnology (01-06-2021)“…Microalgal contamination in algal culture is a serious problem hampering the cultivation process, which can result in considerable economic and time losses…”
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Isolation of Mycosporine-like Amino Acids from Red Macroalgae and a Marine Lichen by High-Performance Countercurrent Chromatography: A Strategy to Obtain Biological UV-Filters
Published in Marine drugs (01-06-2023)“…Marine organisms have gained considerable biotechnological interest in recent years due to their wide variety of bioactive compounds with potential…”
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Hibberdia magna (Chrysophyceae): a promising freshwater fucoxanthin and polyunsaturated fatty acid producer
Published in Microbial cell factories (19-04-2023)“…Algae are prominent producers of carotenoids and polyunsaturated fatty acids which are greatly prized in the food and pharmaceutic industry. Fucoxanthin…”
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Discovery of Unusual Cyanobacterial Tryptophan-Containing Anabaenopeptins by MS/MS-Based Molecular Networking
Published in Molecules (Basel, Switzerland) (20-08-2020)“…Heterocytous cyanobacteria are among the most prolific sources of bioactive secondary metabolites, including anabaenopeptins (APTs). A terrestrial filamentous…”
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Insight into Unprecedented Diversity of Cyanopeptides in Eutrophic Ponds Using an MS/MS Networking Approach
Published in Toxins (31-08-2020)“…Man-made shallow fishponds in the Czech Republic have been facing high eutrophication since the 1950s. Anthropogenic eutrophication and feeding of fish have…”
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Production of Fucoxanthin from Phaeodactylum tricornutum Using High Performance Countercurrent Chromatography Retaining Its FOXO3 Nuclear Translocation-Inducing Effect
Published in Marine drugs (11-09-2021)“…is a rich source of fucoxanthin, a carotenoid with several health benefits. In the present study, high performance countercurrent chromatography (HPCCC) was…”
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The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells
Published in PloS one (02-03-2017)“…Oxadiazines are heterocyclic compounds containing N-N-O or N-N-C-O system within a six membered ring. These structures have been up to now exclusively prepared…”
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Recommendations on the quantitative analysis of pheophorbides, photosensitizers present in algal biomass intended as food supplement
Published in Algal research (Amsterdam) (01-06-2021)“…Pheophorbide a is the major photosensitizer present in algal biomass and its presence in food supplement was linked to human health issues in the past…”
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Screening of the Medicines for Malaria Venture Pandemic Response Box for Discovery of Antivirulent Drug against Pseudomonas aeruginosa
Published in Microbiology spectrum (21-12-2022)“…Resistance development and exhaustion of the arsenal of existing antibacterial agents urgently require an alternative approach toward drug discovery. Herein,…”
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Application of HPCCC Combined with Polymeric Resins and HPLC for the Separation of Cyclic Lipopeptides Muscotoxins A⁻C and Their Antimicrobial Activity
Published in Molecules (Basel, Switzerland) (16-10-2018)“…Muscotoxins are cyanobacterial cyclic lipopeptides with potential applications in biomedicine and biotechnology. In this study, CCALA125 strain extracts were…”
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Phylogenetic and morphological evaluation of the genera Anabaena, Aphanizomenon, Trichormus and Nostoc (Nostocales, Cyanobacteria)
Published in International journal of systematic and evolutionary microbiology (01-01-2005)“…1 Department of Applied Chemistry and Microbiology, Viikki Biocenter, PO Box 56, FI-00014 University of Helsinki, Finland 2 University of South Bohemia,…”
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Discovery of a Pederin Family Compound in a Nonsymbiotic Bloom-Forming Cyanobacterium
Published in ACS chemical biology (18-05-2018)“…The pederin family includes a number of bioactive compounds isolated from symbiotic organisms of diverse evolutionary origin. Pederin is linked to…”
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Separation of the Glycosylated Carotenoid Myxoxanthophyll from Synechocystis Salina by HPCCC and Evaluation of Its Antioxidant, Tyrosinase Inhibitory and Immune-Stimulating Properties
Published in Separations (01-12-2020)“…Global demand for natural pigments has increased in the past few years. Myxoxanthophyll, a glycosylated monocyclic carotenoid, is a pigment that occurs…”
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Isolation, Genomic and Metabolomic Characterization of Streptomyces tendae VITAKN with Quorum Sensing Inhibitory Activity from Southern India
Published in Microorganisms (Basel) (16-01-2020)“…are among the most promising genera in terms of production ability to biosynthesize a variety of bioactive secondary metabolites with pharmaceutical interest…”
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Raman Microspectroscopic Analysis of Selenium Bioaccumulation by Green Alga Chlorella vulgaris
Published in Biosensors (Basel) (10-04-2021)“…Selenium (Se) is an element with many commercial applications as well as an essential micronutrient. Dietary Se has antioxidant properties and it is known to…”
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