Search Results - "Hristov, Delyan R"

Designing Paper-Based Immunoassays for Biomedical Applications by Hristov, Delyan R, Rodriguez-Quijada, Cristina, Gomez-Marquez, Jose, Hamad-Schifferli, Kimberly

“…Paper-based sensors and assays have been highly attractive for numerous biological applications, including rapid diagnostics and assays for disease detection,…”
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Identification of Receptor Binding to the Biomolecular Corona of Nanoparticles by Lara, Sandra, Alnasser, Fatima, Polo, Ester, Garry, David, Lo Giudice, Maria Cristina, Hristov, Delyan R, Rocks, Louise, Salvati, Anna, Yan, Yan, Dawson, Kenneth A

“…Biomolecules adsorbed on nanoparticles are known to confer a biological identity to nanoparticles, mediating the interactions with cells and biological…”
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Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies by McCartney, Fiona, Jannin, Vincent, Chevrier, Stéphanie, Boulghobra, Hakime, Hristov, Delyan R., Ritter, Nicolas, Miolane, Cédric, Chavant, Yann, Demarne, Frédéric, Brayden, David J.

“…Labrasol® ALF (Labrasol®), is a non-ionic surfactant excipient primarily used as a solubilising agent. It was investigated here as an intestinal permeation…”
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Efficacy assessment of self-assembled PLGA-PEG-PLGA nanoparticles: Correlation of nano-bio interface interactions, biodistribution, internalization and gene expression studies by Dimchevska, Simona, Geskovski, Nikola, Koliqi, Rozafa, Matevska-Geskovska, Nadica, Gomez Vallejo, Vanessa, Szczupak, Boguslaw, Sebastian, Eneko San, Llop, Jordi, Hristov, Delyan R., Monopoli, Marco P., Petruševski, Gjorgji, Ugarkovic, Sonja, Dimovski, Aleksandar, Goracinova, Katerina

“…[Display omitted] The aim of our study was to develop and compare the biological performance of two types of biodegradable SN-38 loaded nanoparticles (NPs)…”
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Add Sugar to Chitosan: Mucoadhesion and In Vitro Intestinal Permeability of Mannosylated Chitosan Nanocarriers by Ejaz, Sadaf, Hogg, Bridget, Hristov, Delyan R, Brayden, David J, Imran, Muhammad, Bhattacharjee, Sourav

“…Crosslinked chitosan nanocarriers (140-160 nm) entrapping coumarin-6 ( = 455/508 nm) with or without surface mannosylation were synthesized and assessed for…”
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Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers by Ye, Dong, Bramini, Mattia, Hristov, Delyan R, Wan, Sha, Salvati, Anna, Åberg, Christoffer, Dawson, Kenneth A

“…Cellular barriers, such as the skin, the lung epithelium or the intestinal epithelium, constitute one of the first obstacles facing nanomedicines or other…”
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PEO-PPO-PEO/Poly(DL-lactide-co-caprolactone) Nanoparticles as Carriers for SN-38: Design, Optimization and Nano-Bio Interface Interactions by Koliqi, Rozafa, Dimchevska, Simona, Geskovski, Nikola, Petruševski, Gjorgji, Chacorovska, Marina, Pejova, Biljana, Hristov, Delyan R, Ugarkovic, Sonja, Goracinova, Katerina

“…Encapsulation of extremely hydrophobic substances such as SN-38 into nanoparticles, is a promising approach to solve the solubility issue and enable drug…”
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Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface by Salvati, Anna, Pitek, Andrzej S., Monopoli, Marco P., Prapainop, Kanlaya, Bombelli, Francesca Baldelli, Hristov, Delyan R., Kelly, Philip M., Åberg, Christoffer, Mahon, Eugene, Dawson, Kenneth A.

“…Nanoparticles have been proposed as carriers for drugs, genes and therapies to treat various diseases 1 , 2 . Many strategies have been developed to target…”
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Mapping of Molecular Structure of the Nanoscale Surface in Bionanoparticles by Herda, Luciana M, Hristov, Delyan R, Lo Giudice, Maria Cristina, Polo, Ester, Dawson, Kenneth A

“…Characterizing the orientation of covalently conjugated proteins on nanoparticles, produced for in vitro and in vivo targeting, though an important feature of…”
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The Immunoprobe Aggregation State is Central to Dipstick Immunoassay Performance by Hristov, Delyan R, Pimentel, Alyssa Jean, Ujialele, Godwin, Hamad-Schifferli, Kimberly

“…As new infectious disease outbreaks become more likely, it is important to be able to develop and deploy appropriate testing in time. Paper-based immunoassays…”
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Stabilising fluorescent silica nanoparticles against dissolution effects for biological studies by Mahon, Eugene, Hristov, Delyan R, Dawson, Kenneth A

“…Here we show that commonly employed Stöber type fluorescently labelled silica nanoprobes degrade by hydrolytic dissolution, accelerated under biological media…”
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Impact of dynamic sub-populations within grafted chains on the protein binding and colloidal stability of PEGylated nanoparticles by Hristov, Delyan R, Lopez, Hender, Ortin, Yannick, O'Sullivan, Kate, Dawson, Kenneth A, Brougham, Dermot F

“…Polyethylene glycol grafting has played a central role in preparing the surfaces of nano-probes for biological interaction, to extend blood circulation times…”
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Tuning of nanoparticle biological functionality through controlled surface chemistry and characterisation at the bioconjugated nanoparticle surface by Hristov, Delyan R., Rocks, Louise, Kelly, Philip M., Thomas, Steffi S., Pitek, Andrzej S., Verderio, Paolo, Mahon, Eugene, Dawson, Kenneth A.

“…We have used a silica – PEG based bionanoconjugate synthetic scheme to study the subtle connection between cell receptor specific recognition and architecture…”
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SARS-CoV-2 and approaches for a testing and diagnostic strategy by Hristov, Delyan R, Gomez-Marquez, Jose, Wade, Djibril, Hamad-Schifferli, Kimberly

“…The COVID-19 pandemic has led to an unprecedented global health challenge, creating sudden, massive demands for diagnostic testing, treatment, therapies, and…”
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Using single nanoparticle tracking obtained by nanophotonic force microscopy to simultaneously characterize nanoparticle size distribution and nanoparticle-surface interactions by Hristov, Delyan R, Ye, Dong, de Araújo, Joao Medeiros, Ashcroft, Colby, DiPaolo, Brian, Hart, Robert, Earhart, Christopher, Lopez, Hender, Dawson, Kenneth A

“…Comprehensive characterization of nanomaterials for medical applications is a challenging and complex task due to the multitude of parameters which need to be…”
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