Search Results - "Hoyte, R. M"

A direct stereoselective synthesis of 7β-hydroxytestosterone by Labaree, David, Hoyte, Robert M., Hochberg, Richard B.

“…Although 7β-hydroxytestosterone is a known product of hepatic androgen metabolism, there are no published methods for its chemical synthesis except from the…”
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Iodinated and fluorinated steroid 2′-aryl-[3,2-c] pyrazoles as potential glucocorticoid receptor imaging agents by Hoyte, Robert M, Labaree, David C, Fede, Jean-Marie, Harris, Cathy, Hochberg, Richard B

“…We have synthesized several halogenated steroids as potential glucocorticoid receptor mediated imaging agents. These compounds are analogs of aryl-pyrazolo…”
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Synthesis and evaluation of 7α-iodo-5α-dihydrotestosterone as a potential radioligand for androgen receptor by HOYTE, R. M, BORDERON, K, BRYSON, K, ALLEN, R, HOCHBERG, R. B, BROWN, T. J

“…7 alpha-Iodo-17 beta-hydroxy-5 alpha-androstan-3-one (7 alpha-iodo-5 alpha-dihydrotestosterone, 7 alpha-IDHT) has been synthesized as a potential radioligand…”
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Synthesis and evaluation of potential radioligands for the progesterone receptor by Hoyte, R. M, Rosner, W, Johnson, I. S, Zielinski, J, Hochberg, R. B

“…Several steroidal analogues were synthesized as potential gamma-emitting radioligands for the progesterone receptor. Each of these compounds was tested as an…”
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E-17 alpha-(2-[125I]iodovinyl)-19-nortestosterone: the synthesis of a gamma-emitting ligand for the progesterone receptor by Hochberg, R B, Hoyte, R M, Rosner, W

“…We have synthesized a gamma-emitting steroid, E-17 alpha-(2-[125I]iodovinyl)-19-nortestosterone (E-IVNT), which is a useful ligand for the sensitive and…”
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Synthesis of 16 alpha-[125I] iodo-5 alpha dihydrotestosterone and evaluation of its affinity for the androgen receptor by Hoyte, R M, Rosner, W, Hochberg, R B

“…Analogs of 5 alpha-dihydrotestosterone, halogenated at carbon 11, were synthesized as potential gamma-emitting ligands for the androgen receptor. These…”
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Enzymatic side chain cleavage of C-20 alkyl and aryl analogs of (20-S)-20-hydroxycholesterol. Implications for the biosynthesis of pregnenolone by Hoyte, R M, Hochberg, R B

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7 alpha-iodine-125-iodo-5 alpha-dihydrotestosterone: a radiolabeled ligand for the androgen receptor by Labaree, D C, Brown, T J, Hoyte, R M, Hochberg, R B

“…We describe the preparation of 7 alpha-[125I]iodo-5 alpha-dihydrotestosterone (7 alpha-[125I]IDHT) and its characterization as a ligand for the androgen…”
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Organic Radiopharmaceuticals Labeled with Isotopes of Short Half-Life I: 11C-1-Dopamine Hydrochloride by Christman, D. R, Hoyte, R. M, Wolf, A. P

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7 alpha-Methyl-17 alpha-(E-2'-[125I]iodovinyl)-19-nortestosterone: a new radioligand for the detection of androgen receptor by Hoyte, R M, Brown, T J, MacLusky, N J, Hochberg, R B

“…We have synthesized two gamma-emitting, 125I-labeled steroids, E- and Z-7 alpha-methyl-17 alpha-(2'-[125I]iodovinyl)-19-nortestosterone [125I](E- and Z-MIVNT)…”
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The synthesis and testing of E-17 alpha-(2-iodovinyl)-5 alpha-dihydrotestosterone and Z-17 alpha-(2-iodovinyl)-5 alpha-dihydrotestosterone as gamma-emitting ligands for the androgen receptor by Hoyte, R M, MacLusky, N J, Hochberg, R B

“…Two iodinated steroids, E-17 alpha-(2-iodovinyl)-5 alpha-dihydrotestosterone and Z-17 alpha-(2-iodovinyl)-5 alpha-dihydrotestosterone were synthesized in a…”
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delta 9-[16 alpha-125I]iodo-19-nortestosterone: a gamma-emitting photoaffinity label for the progesterone receptor by Lamb, D J, Bullock, D W, Hoyte, R M, Hochberg, R B

“…We have synthesized 16 alpha-iodo-4,9-estradien-17 beta-ol-3-one [delta 9-16 alpha-iodo-19-nortestosterone (delta 9-INT)] labeled with 125I (delta 9-[16…”
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Bringing science back to the neighborhood by Hoyte, R M

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Response by Hoyte, R. M.

“…Abstract only…”
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Organic radiopharmaceuticals labeled with short-lived nuclides. 3. 18F-labeled phenylalanines by Hoyte, R M, Lin, S S, Christman, D R, Atkins, H L, Hauser, W, Wolf, A P

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Organic radiopharmaceuticals labeled with isotopes of short half-life. V. 18 F-labeled 5- and 6-fluorotryptophan by Atkins, H L, Christman, D R, Fowler, J S, Hauser, W, Hoyte, R M, Klopper, J F, Lin, S S, Wolf, A P

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7α-Iodo and 7α-Fluoro Steroids as Androgen Receptor-Mediated Imaging Agents by Labaree, David C, Hoyte, Robert M, Nazareth, Lynne V, Weigel, Nancy L, Hochberg, Richard B

“…We have synthesized several 7α-fluoro (F) and 7α-iodo (I) analogues of 5α-dihydrotestosterone (5α-DHT) and 19-nor-5α-dihydrotestosterone (5α-NDHT) and tested…”
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7alpha-Iodo and 7alpha-fluoro steroids as androgen receptor-mediated imaging agents by Labaree, D C, Hoyte, R M, Nazareth, L V, Weigel, N L, Hochberg, R B

“…We have synthesized several 7alpha-fluoro (F) and 7alpha-iodo (I) analogues of 5alpha-dihydrotestosterone (5alpha-DHT) and 19-nor-5alpha-dihydrotestosterone…”
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alpha -Iodo and 7 alpha -Fluoro Steroids as Androgen Receptor-Mediated Imaging Agents by Labaree, D C, Hoyte, R M, Nazareth, LV, Weigel, N L, Hochberg, R B

“…We have synthesized several 7 alpha -fluoro (F) and 7 alpha -iodo (I) analogues of 5 alpha -dihydrotestosterone (5 alpha -DHT) and 19-nor-5 alpha…”
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[7alpha-18F]fluoro-17alpha-methyl-5alpha-dihydrotestosterone: a ligand for androgen receptor-mediated imaging of prostate cancer by Garg, P K, Labaree, D C, Hoyte, R M, Hochberg, R B

“…We have synthesized a 18F-labeled androgen, [7alpha-18F]fluoro-17alpha-methyl-5alpha-dihydrotestosterone, in a no-carrier-added radiosynthesis by exchange of…”
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