Search Results - "Hoyt, Martin A"

Functional Asymmetries of Proteasome Translocase Pore by Erales, Jenny, Hoyt, Martin A., Troll, Fabian, Coffino, Philip

“…Degradation by proteasomes involves coupled translocation and unfolding of its protein substrates. Six distinct but paralogous proteasome ATPase proteins, Rpt1…”
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Reconfiguration of the proteasome during chaperone-mediated assembly by Park, Soyeon, Li, Xueming, Kim, Ho Min, Singh, Chingakham Ranjit, Tian, Geng, Hoyt, Martin A., Lovell, Scott, Battaile, Kevin P., Zolkiewski, Michal, Coffino, Philip, Roelofs, Jeroen, Cheng, Yifan, Finley, Daniel

“…The proteasome degrades ubiquitin-conjugated substrates; here, structural and functional insights from studies in yeast reveal that it is reconfigured during…”
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Structural elements of the ubiquitin-independent proteasome degron of ornithine decarboxylase by Takeuchi, Junko, Chen, Hui, Hoyt, Martin A, Coffino, Philip

“…Mouse ODC (ornithine decarboxylase) is quickly degraded by the 26S proteasome in mammalian and fungal cells. Its degradation is independent of ubiquitin but…”
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Glycine-alanine repeats impair proper substrate unfolding by the proteasome by Hoyt, Martin A, Zich, Judith, Takeuchi, Junko, Zhang, Mingsheng, Govaerts, Cedric, Coffino, Philip

“…Proteasome ATPases unravel folded proteins. Introducing a sequence containing only glycine and alanine residues (GAr) into substrates can impair their…”
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Ubiquitin-independent Mechanisms of Mouse Ornithine Decarboxylase Degradation Are Conserved between Mammalian and Fungal Cells by Hoyt, Martin A, Zhang, Mingsheng, Coffino, Philip

“…The polyamine biosynthetic enzyme ornithine decarboxylase (ODC) is degraded by the 26 S proteasome via a ubiquitin-independent pathway in mammalian cells. Its…”
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Proteasomes Begin Ornithine Decarboxylase Digestion at the C Terminus by Zhang, Mingsheng, MacDonald, Alasdair I, Hoyt, Martin A, Coffino, Philip

“…Proteasomes denature folded protein substrates and thread them through a narrow pore that leads to the sequestered sites of proteolysis. Whether a protein…”
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genetic screen for Saccharomyces cerevisiae mutants affecting proteasome function, using a ubiquitin-independent substrate by Hoyt, Martin A, McDonough, Stephen, Pimpl, Stephan A, Scheel, Hartmut, Hofmann, Kay, Coffino, Philip

“…The great majority of proteasome substrates are marked for degradation by the attachment of polyubiquitin chains. Ornithine decarboxylase is degraded by the…”
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Dependence of Proteasome Processing Rate on Substrate Unfolding by Henderson, Allen, Erales, Jenny, Hoyt, Martin A., Coffino, Philip

“…Protein degradation by eukaryotic proteasomes is a multi-step process involving substrate recognition, ATP-dependent unfolding, translocation into the…”
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Ordering an Engagement Ring by Hoyt, Martin A., Coffino, Philip

“…In this issue of Molecular Cell, Tomko et al. (2010) establish that the six distinct ATPase subunits of the eukaryotic proteasome form a heterohexameric ring…”
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Probing the ubiquitin/proteasome system with ornithine decarboxylase, a ubiquitin-independent substrate by Hoyt, Martin A, Zhang, Mingsheng, Coffino, Philip

“…Ornithine decarboxylase (ODC) is an unusual proteasome substrate-ubiquitin conjugation plays no part in its turnover. It can therefore be used as a probe to…”
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An easily dissociated 26 S proteasome catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei by Li, Ziyin, Zou, Chun-Bin, Yao, Yi, Hoyt, Martin A, McDonough, Stephen, Mackey, Zachary B, Coffino, Philip, Wang, Ching C

“…The 26 S proteasome, a complex between the 20 S proteasome and 19 S regulatory units, catalyzes ATP-dependent degradation of unfolded and ubiquitinated…”
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Polyamine Regulation of Ornithine Decarboxylase Synthesis in Neurospora crassa by Hoyt, Martin A., Broun, Mariya, Davis, Rowland H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An Easily Dissociated 26 S Proteasome Catalyzes an Essential Ubiquitin-mediated Protein Degradation Pathway in Trypanosoma brucei by Ziyin Li, Chun-Bin Zou, Yi Yao, Martin A. Hoyt, Stephen McDonough, Zachary B. Mackey, Philip Coffino, Ching C. Wang

“…The 26 S proteasome, a complex between the 20 S proteasome and 19 S regulatory units, catalyzes ATP-dependent degradation of unfolded and ubiquitinated…”
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An Easily Dissociated 26 S Proteasome Catalyzes an Essential Ubiquitin-mediated Protein Degradation Pathway in Trypanosoma brucei210 by Li, Ziyin, Zou, Chun-Bin, Yao, Yi, Hoyt, Martin A., McDonough, Stephen, Mackey, Zachary B., Coffino, Philip, Wang, Ching C.

“…The 26 S proteasome, a complex between the 20 S proteasome and 19 S regulatory units, catalyzes ATP-dependent degradation of unfolded and ubiquitinated…”
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Role of hypothalamic paraventricular nucleus alpha- and beta-adrenergic receptors in regulation of blood glucose, free fatty acids and corticosterone by Gunion, M W, Rosenthal, M J, Miller, S, Hoyt, M A, Yonzon, D B

“…The potential roles of adrenergic and noradrenergic terminals in the hypothalamic paraventricular nucleus in the regulation of blood glucose and free fatty…”
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