Search Results - "Hoyt, A. M."

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    Ubiquitin-proteasome system: Ubiquitin-free routes into the proteasome by Hoyt, M.A., Coffino, P.

    “…The majority of proteasome substrates identified to date are marked for degradation by polyubiquitinylation. Exceptions to this principle, however, are well…”
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    Mid-anaphase arrest in S. cerevisiae cells eliminated for the function of Cin8 and dynein by Gerson-Gurwitz, A, Movshovich, N, Avunie, R, Fridman, V, Moyal, K, Katz, B, Hoyt, M. A, Gheber, L

    “…S. cerevisiae anaphase spindle elongation is accomplished by the overlapping function of dynein and the kinesin-5 motor proteins, Cin8 and Kip1. Cin8 and…”
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    Cell cycle-dependent degradation of the Saccharomyces cerevisiae spindle motor Cin8p requires APC(Cdh1) and a bipartite destruction sequence by Hildebrandt, E R, Hoyt, M A

    Published in Molecular biology of the cell (01-11-2001)
    “…Saccharomyces cerevisiae Cin8p belongs to the BimC family of kinesin-related motor proteins that are essential for spindle assembly. Cin8p levels were found to…”
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    Ubiquitin-free routes into the proteasome by Hoyt, M A, Coffino, P

    “…The majority of proteasome substrates identified to date are marked for degradation by polyubiquitinylation. Exceptions to this principle, however, are well…”
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    Mitotic spindle function in Saccharomyces cerevisiae requires a balance between different types of kinesin-related motors by Saunders, W, Lengyel, V, Hoyt, M A

    Published in Molecular biology of the cell (01-06-1997)
    “…Two Saccharomyces cerevisiae kinesin-related motors, Cin8p and Kip1p, perform an essential role in the separation of spindle poles during spindle assembly and…”
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    Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly by Hoyt, M. Andrew, He, Ling, Loo, Kek Khee, Saunders, William S.

    Published in The Journal of cell biology (01-07-1992)
    “…Two Saccharomyces cerevisiae genes, CIN8 and KIP1 (a.k.a. CIN9), were identified by their requirement for normal chromosome segregation. Both genes encode…”
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    STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H+-ATPase subunit Vph1p by Manolson, M.F, Wu, B, Proteau, D, Taillon, B.E, Roberts, B.T, Hoyt, M.A, Jones, E.W

    Published in The Journal of biological chemistry (13-05-1994)
    “…The Saccharomyces cerevisiae gene, VPH1 (Vacuolar pH 1), encodes a 95-kDa integral membrane subunit of the vacuolar-type H+-ATPase (V-ATPase) that is required…”
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    The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase by Roberts, B T, Farr, K A, Hoyt, M A

    Published in Molecular and Cellular Biology (01-12-1994)
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    Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways by Geiser, J R, Schott, E J, Kingsbury, T J, Cole, N B, Totis, L J, Bhattacharyya, G, He, L, Hoyt, M A

    Published in Molecular biology of the cell (01-06-1997)
    “…Kinesin-related Cin8p is the most important spindle-pole-separating motor in Saccharomyces cerevisiae but is not essential for cell viability. We identified 20…”
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    Altered dosage of the Saccharomyces cerevisiae spindle pole body duplication gene, NDC1, leads to aneuploidy and polyploidy by Chial, H.J, Giddings, T.H. Jr, Siewert, E.A, Hoyt, M.A, Winey, M

    “…Saccharomyces cerevisiae cells are exquisitely sensitive to altered dosage of the spindle pole body duplication gene, NDC1. We show that the NDC1 locus is…”
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    NDC1: a nuclear periphery component required for yeast spindle pole body duplication by Winey, M, Hoyt, M.A, Chan, C, Goetsch, L, Botstein, D, Byers, B

    Published in The Journal of cell biology (01-08-1993)
    “…The spindle pole body (SPB) of Saccharomyces cerevisiae serves as the centrosome in this organism, undergoing duplication early in the cell cycle to generate…”
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    Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations by Hoyt, M.A, He, L, Totis, L, Saunders, W.S

    Published in Genetics (Austin) (01-09-1993)
    “…The kinesin-related products of the CIN8 and KIP1 genes of Saccharomyces cerevisiae redundantly perform an essential function in mitosis. The action of either…”
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    The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H+-ATPase by Manolson, M.F. (Carnegie Mellon University, Pittsburgh, PA), Proteau, D, Preston, R.A, Stenbit, A, Roberts, B.T, Hoyt, M.A, Preuss, D, Mulholland, J, Botstein, D, Jones, E.W

    Published in The Journal of biological chemistry (15-07-1992)
    “…Yeast vacuolar acidification -defective (vph) mutants were identified using the pH-sensitive fluorescence of 6-carboxyfluorescein diacetate (Preston, R. A.,…”
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    Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation by Saunders, W.S. (University of Pittsburgh, Pittsburgh, PA.), Koshland, D, Eshel, D, Gibbons, I.R, Hoyt, M.A

    Published in The Journal of cell biology (01-02-1995)
    “…The Saccharomyces cerevisiae kinesin-related gene products Cin8p and Kip1p function to assemble the bipolar mitotic spindle. The cytoplasmic dynein heavy chain…”
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    Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability by Hoyt, M.A. (The Johns Hopkins University, Baltimore, MD.), Macke, J.P, Tibor Roberts, B, Geiser, J.R

    Published in Genetics (Austin) (01-07-1997)
    “…The products of the Saccharomyces cerevisiae CIN1, CIN2 and CIN4 genes participate in a nonessential pathway required for normal microtubule function. In this…”
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    ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes by Stearns, T, Kahn, R A, Botstein, D, Hoyt, M A

    Published in Molecular and Cellular Biology (01-12-1990)
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    Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function by Stearns, T. (Massachusetts Institute of Technology, Cambridge, MA), Hoyt, M.A, Botstein, D

    Published in Genetics (Austin) (01-02-1990)
    “…Three new genes affecting microtubule function in Saccharomyces cerevisiae were isolated by screening for mutants displaying supersensitivity to the…”
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    GENETIC ANALYSIS OF THE MITOTIC SPINDLE by Hoyt, M. Andrew, Geiser, John R

    Published in Annual review of genetics (01-01-1996)
    “…Much of our understanding of the molecular basis of mitotic spindle function has been achieved within the past decade. Studies utilizing genetically tractable…”
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    Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes by Hoyt, M A, Stearns, T, Botstein, D

    Published in Molecular and Cellular Biology (01-01-1990)
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