Search Results - "Hoye, Mariah L."

CNS microRNA profiles: a database for cell type enriched microRNA expression across the mouse central nervous system by Pomper, Nathan, Liu, Yating, Hoye, Mariah L., Dougherty, Joseph D., Miller, Timothy M.

“…microRNAs are short, noncoding RNAs that can regulate hundreds of targets and thus shape the expression landscape of a cell. Similar to mRNA, they often…”
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Aberrant cortical development is driven by impaired cell cycle and translational control in a DDX3X syndrome model by Hoye, Mariah L, Calviello, Lorenzo, Poff, Abigail J, Ejimogu, Nna-Emeka, Newman, Carly R, Montgomery, Maya D, Ou, Jianhong, Floor, Stephen N, Silver, Debra L

“…Mutations in the RNA helicase, , are a leading cause of Intellectual Disability and present as syndrome, a neurodevelopmental disorder associated with cortical…”
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A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X by Jowhar, Ziad, Xu, Albert, Venkataramanan, Srivats, Dossena, Francesco, Hoye, Mariah L, Silver, Debra L, Floor, Stephen N, Calviello, Lorenzo

“…The road from transcription to protein synthesis is paved with many obstacles, allowing for several modes of post-transcriptional regulation of gene…”
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Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology by Reichenstein, Irit, Eitan, Chen, Diaz-Garcia, Sandra, Haim, Guy, Magen, Iddo, Siany, Aviad, Hoye, Mariah L, Rivkin, Natali, Olender, Tsviya, Toth, Beata, Ravid, Revital, Mandelbaum, Amitai D, Yanowski, Eran, Liang, Jing, Rymer, Jeffrey K, Levy, Rivka, Beck, Gilad, Ainbinder, Elena, Farhan, Sali M K, Lennox, Kimberly A, Bode, Nicole M, Behlke, Mark A, Möller, Thomas, Saxena, Smita, Moreno, Cristiane A M, Costaguta, Giancarlo, van Eijk, Kristel R, Phatnani, Hemali, Al-Chalabi, Ammar, Başak, A Nazli, van den Berg, Leonard H, Hardiman, Orla, Landers, John E, Mora, Jesus S, Morrison, Karen E, Shaw, Pamela J, Veldink, Jan H, Pfaff, Samuel L, Yizhar, Ofer, Gross, Christina, Brown, Jr, Robert H, Ravits, John M, Harms, Matthew B, Miller, Timothy M, Hornstein, Eran

“…Motor neuron-specific microRNA-218 (miR-218) has recently received attention because of its roles in mouse development. However, miR-218 relevance to human…”
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Decoding mixed messages in the developing cortex: translational regulation of neural progenitor fate by Hoye, Mariah L, Silver, Debra L

“…Multipotent radial glial cells (RGCs, orange) are transcriptionally primed to enable rapid generation of diverse progeny. Post-transcriptional regulation,…”
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Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development by Lennox, Ashley L., Hoye, Mariah L., Jiang, Ruiji, Johnson-Kerner, Bethany L., Suit, Lindsey A., Venkataramanan, Srivats, Sheehan, Charles J., Alsina, Fernando C., Fregeau, Brieana, Aldinger, Kimberly A., Moey, Ching, Lobach, Iryna, Afenjar, Alexandra, Babovic-Vuksanovic, Dusica, Bézieau, Stéphane, Blackburn, Patrick R., Bunt, Jens, Burglen, Lydie, Campeau, Philippe M., Charles, Perrine, Chung, Brian H.Y., Cogné, Benjamin, Curry, Cynthia, D’Agostino, Maria Daniela, Di Donato, Nataliya, Faivre, Laurence, Héron, Delphine, Innes, A. Micheil, Isidor, Bertrand, Keren, Boris, Kimball, Amy, Klee, Eric W., Kuentz, Paul, Küry, Sébastien, Martin-Coignard, Dominique, Mirzaa, Ghayda, Mignot, Cyril, Miyake, Noriko, Matsumoto, Naomichi, Fujita, Atsushi, Nava, Caroline, Nizon, Mathilde, Rodriguez, Diana, Blok, Lot Snijders, Thauvin-Robinet, Christel, Thevenon, Julien, Vincent, Marie, Ziegler, Alban, Dobyns, William, Richards, Linda J., Barkovich, A. James, Floor, Stephen N., Silver, Debra L., Sherr, Elliott H.

“…De novo germline mutations in the RNA helicase DDX3X account for 1%–3% of unexplained intellectual disability (ID) cases in females and are associated with…”
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Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis by Hoye, Mariah L, Regan, Melissa R, Jensen, Leah A, Lake, Allison M, Reddy, Linga V, Vidensky, Svetlana, Richard, Jean-Philippe, Maragakis, Nicholas J, Rothstein, Jeffrey D, Dougherty, Joseph D, Miller, Timothy M

“…See Ferraiuolo and Shaw (doi:10.1093/brain/awy213) for a scientific commentary on this article. The death of motor neurons in ALS triggers changes in…”
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MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models by Hoye, Mariah L, Koval, Erica D, Wegener, Amy J, Hyman, Theodore S, Yang, Chengran, O'Brien, David R, Miller, Rebecca L, Cole, Tracy, Schoch, Kathleen M, Shen, Tao, Kunikata, Tomonori, Richard, Jean-Philippe, Gutmann, David H, Maragakis, Nicholas J, Kordasiewicz, Holly B, Dougherty, Joseph D, Miller, Timothy M

“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder marked by the loss of motor neurons (MNs) in the brain and spinal cord, leading…”
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From Methods to Monographs: Fostering a Culture of Research Quality by Crawford, Devon C, Hoye, Mariah L, Silberberg, Shai D

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MicroRNA signature of central nervous system‐infiltrating dendritic cells in an animal model of multiple sclerosis by Hoye, Mariah L., Archambault, Angela S., Gordon, Taylor M., Oetjen, Landon K., Cain, Matthew D., Klein, Robyn S., Crosby, Seth D., Kim, Brian S., Miller, Timothy M., Wu, Gregory F.

“…Summary Innate immune cells are integral to the pathogenesis of several diseases of the central nervous system (CNS), including multiple sclerosis (MS)…”
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Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models by McCampbell, Alex, Cole, Tracy, Wegener, Amy J, Tomassy, Giulio S, Setnicka, Amy, Farley, Brandon J, Schoch, Kathleen M, Hoye, Mariah L, Shabsovich, Mark, Sun, Linhong, Luo, Yi, Zhang, Mingdi, Comfort, Nicole, Wang, Bin, Amacker, Jessica, Thankamony, Sai, Salzman, David W, Cudkowicz, Merit, Graham, Danielle L, Bennett, C Frank, Kordasiewicz, Holly B, Swayze, Eric E, Miller, Timothy M

“…Mutations in superoxide dismutase 1 (SOD1) are responsible for 20% of familial ALS. Given the gain of toxic function in this dominantly inherited disease,…”
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