Search Results - "Hoxie, Irene"
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Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater
Published in Nature communications (03-02-2022)“…Tracking SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection may lead to the emergence of novel variants resistant to naturally…”
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Rotavirus A Genome Segments Show Distinct Segregation and Codon Usage Patterns
Published in Viruses (27-07-2021)“…Reassortment of the Rotavirus A (RVA) 11-segment dsRNA genome may generate new genome constellations that allow RVA to expand its host range or evade immune…”
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Protocol for safe, affordable, and reproducible isolation and quantitation of SARS-CoV-2 RNA from wastewater
Published in PloS one (23-09-2021)“…The following protocol describes our workflow for processing wastewater with the goal of detecting the genetic signal of SARS-CoV-2. The steps include…”
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Intragenic recombination influences rotavirus diversity and evolution
Published in Virus evolution (01-01-2020)“…Abstract Because of their replication mode and segmented dsRNA genome, homologous recombination is assumed to be rare in the rotaviruses. We analyzed 23,627…”
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Increased efficacy of influenza virus vaccine candidate through display of recombinant neuraminidase on virus like particles
Published in Frontiers in immunology (10-06-2024)“…Vaccination against influenza virus can reduce the risk of influenza by 40% to 60%, they rely on the production of neutralizing antibodies specific to…”
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Publisher Correction: Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater
Published in Nature communications (30-03-2022)Get full text
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Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City
Published in Journal of virology (13-06-2024)“…Highly pathogenic avian influenza viruses of the H5N1 clade 2.3.4.4b were detected in North America in the winter of 2021/2022. These viruses have spread…”
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A recombinant N2 neuraminidase-based CpG 1018® adjuvanted vaccine provides protection against challenge with heterologous influenza viruses in mice and hamsters
Published in Vaccine (24-10-2024)“…Recombinant influenza virus neuraminidase (NA) is a promising broadly protective influenza vaccine candidate. However, the recombinant protein alone is not…”
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Enhancing NA immunogenicity through novel VLP designs
Published in Vaccine (24-10-2024)“…Current influenza virus vaccines poorly display key neuraminidase (NA) epitopes and do not robustly induce NA-reactive antibodies; instead, they focus on the…”
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Reviewing as a career milestone: a discussion on the importance of including trainees in the peer review process
Published in Communications biology (24-09-2021)“…In celebration of Peer Review Week 2021, we asked pairs of faculty mentors and their trainees to reflect on their experiences as co-reviewers for manuscripts…”
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Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination
Published in Cell reports (Cambridge) (26-11-2024)“…Neutralizing antibodies correlate with protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Recent studies, however, show that…”
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