Search Results - "Hoxie, A."

Combustion characteristics of ternary fuel Blends: Pentanol, butanol and vegetable oil by Coughlin, B., Hoxie, A.

“…Ternary blends of pentanol, butanol and soybean oil are investigated and compared to binary blends of pentanol/soybean oil and butanol/soybean oil. Ternary…”
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Evaluating high volume blends of vegetable oil in micro-gas turbine engines by Hoxie, A., Anderson, M.

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Microexplosive combustion behavior of blended soybean oil and butanol droplets by Hoxie, A., Schoo, R., Braden, J.

“…•We analyze single droplet combustion behavior of RBD soybean oil-butanol blends.•Ignition temperatures correspond to pure butanol for mixtures of 25% butanol…”
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Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques by Santangelo, Philip J, Rogers, Kenneth A, Zurla, Chiara, Blanchard, Emmeline L, Gumber, Sanjeev, Strait, Karen, Connor-Stroud, Fawn, Schuster, David M, Amancha, Praveen K, Hong, Jung Joo, Byrareddy, Siddappa N, Hoxie, James A, Vidakovic, Brani, Ansari, Aftab A, Hunter, Eric, Villinger, Francois

“…ImmunoPET/CT imaging using a labeled SIV-specific antibody can identify sites of viralinfection in SIV-infected macaques without the need for tissue biopsies,…”
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Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor by Pegu, Amarendra, Yang, Zhi-yong, Boyington, Jeffrey C, Wu, Lan, Ko, Sung-Youl, Schmidt, Stephen D, McKee, Krisha, Kong, Wing-Pui, Shi, Wei, Chen, Xuejun, Todd, John-Paul, Letvin, Norman L, Huang, Jinghe, Nason, Martha C, Hoxie, James A, Kwong, Peter D, Connors, Mark, Rao, Srinivas S, Mascola, John R, Nabel, Gary J

“…HIV-1 infection depends on effective viral entry mediated by the interaction of its envelope (Env) glycoprotein with specific cell surface receptors…”
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Quantification of Entry Phenotypes of Macrophage-Tropic HIV-1 across a Wide Range of CD4 Densities by Joseph, Sarah B, Arrildt, Kathryn T, Swanstrom, Adrienne E, Schnell, Gretja, Lee, Benhur, Hoxie, James A, Swanstrom, Ronald

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Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure by White, Tommi A, Bartesaghi, Alberto, Borgnia, Mario J, Meyerson, Joel R, de la Cruz, M Jason V, Bess, Julian W, Nandwani, Rachna, Hoxie, James A, Lifson, Jeffrey D, Milne, Jacqueline L S, Subramaniam, Sriram

“…The initial step in target cell infection by human, and the closely related simian immunodeficiency viruses (HIV and SIV, respectively) occurs with the binding…”
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Blockade of Lymphocyte Chemotaxis in Visceral Graft-versus-Host Disease by Reshef, Ran, Luger, Selina M, Hexner, Elizabeth O, Loren, Alison W, Frey, Noelle V, Nasta, Sunita D, Goldstein, Steven C, Stadtmauer, Edward A, Smith, Jacqueline, Bailey, Sarah, Mick, Rosemarie, Heitjan, Daniel F, Emerson, Stephen G, Hoxie, James A, Vonderheide, Robert H, Porter, David L

“…Blocking lymphocyte chemotaxis with an oral inhibitor of the CCR5 receptor was associated with reduced incidence of visceral graft-versus-host disease (GVHD)…”
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An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum by FERRARI, Guido, POLLARA, Justin, KAPPES, John C, SHAW, George M, HOXIE, James A, ROBINSON, James E, HAYNES, Barton F, KOZINK, Daniel, HARMS, Tiara, DRINKER, Mark, FREEL, Stephanie, MOODY, M. Anthony, MUNIR ALAM, S, TOMARAS, Georgia D, OCHSENBAUER, Christina

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Tetherin downmodulation by SIVmac Nef lost with the H196Q escape variant is restored by an upstream variant by Schouest, Blake, Leslie, George J, Hoxie, James A, Maness, Nicholas J

“…The H.sub.196 residue in SIVmac239 Nef is conserved across the majority of HIV and SIV isolates, lies immediately adjacent to the AP-2 (adaptor protein 2)…”
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Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis by Moy, Ryan H., Huffman, Austin P., Richman, Lee P., Crisalli, Lisa, Wang, Ximi K., Hoxie, James A., Mick, Rosemarie, Emerson, Stephen G., Zhang, Yi, Vonderheide, Robert H., Porter, David L., Reshef, Ran

“…Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Lymphocyte…”
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HIV Vaccine Research: The Way Forward by Fauci, Anthony S, Johnston, Margaret I, Dieffenbach, Carl W, Burton, Dennis R, Hammer, Scott M, Hoxie, James A, Martin, Malcolm, Overbaugh, Julie, Watkins, David I, Mahmoud, Adel, Greene, Warner C

“…The need to broaden research directed at answering fundamental questions in HIV vaccine discovery through laboratory, nonhuman primate (NHP), and clinical…”
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Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site by XUELING WU, WANG, Charlene, SHAW, George M, WYATT, Richard T, MASCOLA, John R, O'DELL, Sijy, YUXING LI, KEELE, Brandon F, ZHONGJIA YANG, IMAMICHI, Hiromi, DORIA-ROSE, Nicole, HOXIE, James A, CONNORS, Mark

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Novel cell and gene therapies for HIV by Hoxie, James A, June, Carl H

“…Highly active antiretroviral therapy dramatically improves survival in HIV-infected patients. However, persistence of HIV in reservoirs has necessitated…”
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Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8 + T cells by Nguyen, Son, Deleage, Claire, Darko, Samuel, Ransier, Amy, Truong, Duc P, Agarwal, Divyansh, Japp, Alberto Sada, Wu, Vincent H, Kuri-Cervantes, Leticia, Abdel-Mohsen, Mohamed, Del Rio Estrada, Perla M, Ablanedo-Terrazas, Yuria, Gostick, Emma, Hoxie, James A, Zhang, Nancy R, Naji, Ali, Reyes-Terán, Gustavo, Estes, Jacob D, Price, David A, Douek, Daniel C, Deeks, Steven G, Buggert, Marcus, Betts, Michael R

“…The functional properties of circulating CD8 T cells have been associated with immune control of HIV. However, viral replication occurs predominantly in…”
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A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection by Lawrence, Scott P, Elser, Samra E, Torben, Workineh, Blair, Robert V, Pahar, Bapi, Aye, Pyone P, Schiro, Faith, Szeltner, Dawn, Doyle-Meyers, Lara A, Haggarty, Beth S, Jordan, Andrea P O, Romano, Josephine, Leslie, George J, Alvarez, Xavier, O'Connor, David H, Wiseman, Roger W, Fennessey, Christine M, Li, Yuan, Piatak, Jr, Michael, Lifson, Jeffrey D, LaBranche, Celia C, Lackner, Andrew A, Keele, Brandon F, Maness, Nicholas J, Marsh, Mark, Hoxie, James A

“…The HIV/SIV envelope glycoprotein (Env) cytoplasmic domain contains a highly conserved Tyr-based trafficking signal that mediates both clathrin-dependent…”
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DC-SIGN and CLEC-2 Mediate Human Immunodeficiency Virus Type 1 Capture by Platelets by Chaipan, Chawaree, Soilleux, Elizabeth J, Simpson, Peter, Hofmann, Heike, Gramberg, Thomas, Marzi, Andrea, Geier, Martina, Stewart, Elizabeth A, Eisemann, Jutta, Steinkasserer, Alexander, Suzuki-Inoue, Katsue, Fuller, Gemma L, Pearce, Andrew C, Watson, Steve P, Hoxie, James A, Baribaud, Frederic, Pöhlmann, Stefan

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Basic properties of refined, bleached and deodorized soybean oil–butanol blends by Schoo, R., Hoxie, A.

“…► We analyze basic properties of RBD soybean oil–butanol mixtures. ► Mixing rules are established for relative density, viscosity, and HHV. ► An exponential…”
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Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus by Leslie, George J, Wang, Jianbin, Richardson, Max W, Haggarty, Beth S, Hua, Kevin L, Duong, Jennifer, Secreto, Anthony J, Jordon, Andrea P O, Romano, Josephine, Kumar, Kritika E, DeClercq, Joshua J, Gregory, Philip D, June, Carl H, Root, Michael J, Riley, James L, Holmes, Michael C, Hoxie, James A

“…HIV-1 entry can be inhibited by soluble peptides from the gp41 heptad repeat-2 (HR2) domain that interfere with formation of the 6-helix bundle during fusion…”
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Antigenic conservation and immunogenicity of the HIV coreceptor binding site by Decker, Julie M, Bibollet-Ruche, Frederic, Wei, Xiping, Wang, Shuyi, Levy, David N, Wang, Wenquan, Delaporte, Eric, Peeters, Martine, Derdeyn, Cynthia A, Allen, Susan, Hunter, Eric, Saag, Michael S, Hoxie, James A, Hahn, Beatrice H, Kwong, Peter D, Robinson, James E, Shaw, George M

“…Immunogenic, broadly reactive epitopes of the HIV-1 envelope glycoprotein could serve as important targets of the adaptive humoral immune response in natural…”
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