Search Results - "Howland, Kennedy"

Cellular barcoding tracks heterogeneous clones through selective pressures and phenotypic transitions by Howland, Kennedy K, Brock, Amy

“…Genomic DNA barcoding has emerged as a sensitive and flexible tool to measure the fates of clonal subpopulations within a heterogeneous cancer cell population…”
Get more information

Adipogenic Differentiation Alters Properties of Vascularized Tissue-Engineered Skeletal Muscle by Acosta, Francisca M, Howland, Kennedy K, Stojkova, Katerina, Hernandez, Elizabeth, Brey, Eric M, Rathbone, Christopher R

“…Advances in the engineering of comprehensive skeletal muscle models will improve drug screening platforms and can lead to better therapeutic approaches for the…”
Get more information

Diabetic Conditions Confer Metabolic and Structural Modifications to Tissue-Engineered Skeletal Muscle by Acosta, Francisca M, Jia, U-Ter Aonda, Stojkova, Katerina, Howland, Kennedy K, Guda, Teja, Pacelli, Settimio, Brey, Eric M, Rathbone, Christopher R

“…Skeletal muscle is a tissue that is directly involved in the progression and persistence of type 2 diabetes (T2D), a disease that is becoming increasingly…”
Get more information

Abstract B037: ClonMapper Duo: An scRNAseq compatible lineage tracing method to track cell-cell fusion at single-cell resolution by Gardner, Andrea L., Zheng, Lan, Morgan, Daylin, Howland, Kennedy, Brock, Amy

“…Spontaneous cell-cell fusion in cancer can generate genetic heterogeneity and often leads to more pathological phenotypes. While the consequences of cell-cell…”
Get full text

Abstract 122: The subclonal dynamics of gross ploidy alterations in TNBC cells under chemotherapeutic pressure by Gardner, Andrea L., Zheng, Lan, Parker, Patrik, Howland, Kennedy, Morgan, Daylin, Brock, Amy

“…Solid tumors such as triple-negative breast cancer (TNBC) have characteristically high rates of aneuploidy and polyploidy. Chromosome-level aneuploidies are…”
Get full text

Abstract B017: Homotypic cell-cell fusion in TNBC cells downregulates cancer testis antigen MAGEC2 and increases therapeutic sensitivity to paclitaxel and doxorubicin by Gardner, Andrea, Zheng, Lan, Howland, Kennedy, Iloegbunam, Chisom, Barrera, Patrik, De Santiago, Carolina, Brock, Amy

“…This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Proffered Abstracts section (PR007) of the…”
Get full text

Abstract PR007: Homotypic cell-cell fusion in TNBC cells downregulates cancer testis antigen MAGEC2 and increases therapeutic sensitivity to paclitaxel and doxorubicin by Gardner, Andrea, Zheng, Lan, Howland, Kennedy, Iloegbunam, Chisom, Barrera, Patrik, De Santiago, Carolina, Brock, Amy

“…Cell-cell fusion between cancer cells and genetically mismatched populations has been shown to generate genotypic diversity and more pathological phenotypes…”
Get full text