Search Results - "Howerton, Shelley B"
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Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
Published in Nucleic acids research (01-06-2012)“…Cytosine residues in mammalian DNA occur in at least three forms, cytosine (C), 5-methylcytosine (M; 5mC) and 5-hydroxymethylcytosine (H; 5hmC). During…”
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Locating Monovalent Cations in the Grooves of B-DNA
Published in Biochemistry (Easton) (28-08-2001)“…Here we demonstrate that monovalent cations can localize around B-DNA in geometrically regular, sequence-specific sites in oligonucleotide crystals. Positions…”
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High-Resolution Structure of an Extended A-Tract: [d(CGCAAATTTGCG)]2
Published in Journal of the American Chemical Society (01-12-2004)“…The crystal structure of [d(CGCAAATTTGCG)]2 has been determined to 1.5 Å resolution, representing the first high-resolution structure of this DNA fragment. The…”
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Cations Mediate B-DNA Conformational Heterogeneity
Published in Journal of the American Chemical Society (15-11-2000)“…We demonstrate that DNA conformation is sensitive to cationic environment. We describe a high resolution (1.2 Å) potassium form of CGCGAATTCGCG, determined…”
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Automated identification of RNA conformational motifs: theory and application to the HM LSU 23S rRNA
Published in Nucleic acids research (01-11-2003)“…We develop novel methods for recognizing and cataloging conformational states of RNA, and for discovering statistical rules governing those states. We focus on…”
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Monovalent Cations Sequester within the A-Tract Minor Groove of [d(CGCGAATTCGCG)]2
Published in Journal of the American Chemical Society (23-02-2000)Get full text
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Surprising roles of electrostatic interactions in DNA-ligand complexes
Published in Biopolymers (01-05-2003)“…The positions of cations in x‐ray structures are modulated by sequence, conformation, and ligand interactions. The goal here is to use x‐ray diffraction to…”
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Strand Breaks in X-Irradiated Crystalline DNA: Alternating CG Oligomers
Published in Radiation research (01-09-2003)“…Razskazovskiy, Y., Debije, M. G., Howerton, S. B., Williams, L. D. and Bernhard, W. A. Strand Breaks in X-Irradiated Crystalline DNA: Alternating CG Oligomers…”
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