Search Results - "Howells, G. L."

Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo by CICALA, C, PINTO, A, BUCCI, M, SORRENTINO, R, WALKER, B, HARRIOT, P, CRUCHLEY, A, KAPAS, S, HOWELLS, G. L, CIRINO, G

“…The protease-activated receptor-2 (PAR-2) is expressed by vascular endothelial cells and upregulated by lipopolysaccharide (LPS) in vitro. PAR-2 is activated…”
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Immunolocalization of protease‐activated receptor‐2 in skin: receptor activation stimulates interleukin‐8 secretion by keratinocytes in vitro by HOU, L., KAPAS, S., CRUCHLEY, A. T., MACEY, M. G., HARRIOTT, P., CHINNI, C., STONE, S. R., HOWELLS, G. L.

“…The protease‐activated receptor‐2 (PAR‐2) is a seven transmembrane domain receptor related to the thrombin receptor, which is activated in vitro by cleavage by…”
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Platelet-derived interleukin 1 induces human endothelial adhesion molecule expression and cytokine production by HAWRYLOWICZ, C. M, HOWELLS, G. L, FELDMANN, M

“…Interleukin 1 (IL-1) plays a central role in the regulation of the body's response to infectious and inflammatory stimuli. Recent evidence has shown that human…”
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THE PROTEASE‐ACTIVATED RECEPTORS AND THEIR CELLULAR EXPRESSION AND FUNCTION IN BLOOD‐RELATED CELLS by HOU, L, HOWELLS, G. L, KAPAS, S, MACEY, M. G

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Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fibroblasts by Hou, L., Ravenall, S., Macey, M. G., Harriott, P., Kapas, S., Howells, G. L.

“…The serine protease thrombin is formed at sites of coagulation and inflammation and has been shown to have important proinflammatory cellular effects relevant…”
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An immunohistochemical study of keratin expression in ameloblastoma from a Kenyan population by Ong'uti, MN, Howells, GL, Williams, DM

“…OBJECTIVES: Ameloblastomas appear to exhibit biological heterogeneity and, except in the case of malignancy, histological appearances that do not always allow…”
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Ki-67 antigen in ameloblastomas: correlation with clinical and histological parameters in 54 cases from Kenya by Ong'uti, Meshach N., Cruchley, Alan T., Howells, Gareth L., Williams, David M.

“…The aim of this study was to assess the cell proliferation in ameloblastomas and to correlate this with clinical features and histology. Immunohistochemistry…”
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Residues and metabolism of 19-nortestosterone laurate in steers by Sauer, M J, Samuels, T P, Howells, L G, Seymour, M A, Nedderman, A, Houghton, E, Bellworthy, S J, Anderson, S, Coldham, N G

“…The illegal use of 19-nortestosterone (19NT; 4-estren-17 beta-ol-3-one; nandrolone) and its esters in livestock, for growth promotion purposes, has been widely…”
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Interleukin-11 inhibits bone formation in vitro by HUGHES, F. J, HOWELLS, G. L

“…The effects of interleukin-11(IL-11) on the differentiation of osteoblast precursors was tested using a bone nodule forming assay in rat calvaria cell…”
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Human peripheral blood monocytes express protease receptor-2 and respond to receptor activation by production of IL-6, IL-8, and IL-1β by Johansson, Ulrika, Lawson, Charlotte, Dabare, Michael, Syndercombe‐Court, Denise, Newland, Adrian C., Howells, Gareth L., Macey, Marion G.

“…Protease‐activated receptor‐2 (PAR‐2) belongs to a family of G‐coupled receptors activated by proteolytic cleavage to reveal a tethered ligand. PAR‐2 is…”
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A CD4+ proliferation of large granular lymphocytes expresses the protease activated receptor‐1 by MACEY, M. G, HOU, L, MILNE, T, PARAMESWAREN, V, HOWE, D, CAVENAGH, J. D, HOWELLS, G. L, NEWLAND, A. A. C

“…The platelet‐type thrombin receptor was the first member to be identified in a family of protease activated receptors (PARs) and has been designated PAR‐1. We…”
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Malignant ameloblastoma revisited by Newman, L, Howells, G.L, Coghlan, K.M, DiBiase, A, Williams, D.M

“…A case of a malignant ameloblastoma in a 49-year old Sri Lankan woman with widespread pulmonary metastases is presented, the diagnosis confirmed by needle…”
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Analysis of the platelet-type thrombin receptor in 20 cases of large granular lymphocyte proliferations by Macey, M G, Howells, G L, Stone, S R, Newland, A C

“…The platelet-type thrombin receptor was expressed by large granular lymphocytes (LGLs) in a variety of proliferative diseases. Twenty patients with LGL…”
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Peripheral blood lymphocytes express the platelet-type thrombin receptor by Howells, G L, Macey, M, Curtis, M A, Stone, S R

“…Northern blot analysis of human mononuclear cells indicated that the platelet thrombin receptor may be expressed by lymphocytes. In order to investigate this,…”
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Hemangiopericytoma: a report of two cases arising on the lip by Kothari, P.S, Murphy, M, Howells, G.L, Williams, D.M

“…Hemangiopericytoma is a rare tumour of pericytes; represents 1% of all vasoformative tumours and 15–25% of those which occur in the head and neck. We present…”
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Platelet activation by Protease I of Porphyromonas gingivalis W83 by Curtis, M A, Macey, M, Slaney, J M, Howells, G L

“…Porphyromonas gingivalis produces a trypsin-like enzyme, Protease I, which is thought to be an important virulence determinant of the organism in adult…”
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Proteinase-activated receptor-2: expression by human neutrophils by Howells, G L, Macey, M G, Chinni, C, Hou, L, Fox, M T, Harriott, P, Stone, S R

“…Neutrophils were shown to express the proteinase-activated receptor-2 (PAR-2), a seven transmembrane domain receptor, which is activated by cleavage by…”
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Thrombin receptor expression and function in large granular lymphocyte proliferative disorders by Howells, G L, Macey, M, Murrell, A M, Green, A R, Curtis, M A, Stone, S R

“…It has recently been shown that peripheral blood NK-cells and a fraction of T-cells which co-express CD16 and either CD56 or CD57 express the platelet type…”
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Antibodies against monocytes and endothelial cells in the sera of patients with atherosclerotic peripheral arterial disease by D'Anastasio, C, Impallomeni, M, McPherson, G A, Clements, W G, Howells, G L, Brooks, P A, Batchelor, J R

“…We looked for antibodies against endothelial cells, monocytes, fibroblasts, lymphocytes and Epstein-Barr virus transformed lymphocytes in the sera of 28…”
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Cytokine networks in destructive periodontal disease by Howells, G L

“…Cytokines are important regulatory proteins, produced by activated cells, which act by binding high affinity cell surface receptors. They are involved in…”
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