Search Results - "Howells, A J"
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Mutational analysis of the Traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster: implications for structure-function relationships
Published in The Journal of biological chemistry (08-04-1994)“…The white, brown, and scarlet genes of Drosophila melanogaster encodes three proteins that belong to the Traffic ATPase superfamily of transmembrane permeases…”
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The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs
Published in Biochemistry (Easton) (16-03-1993)“…We have cloned and overexpressed a gene encoding a 43-kDa protein corresponding to the N-terminal fragment of the DNA gyrase B subunit. We show that this…”
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Cloning and characterization of the scarlet gene of Drosophila melanogaster
Published in Genetics (Austin) (01-07-1989)“…DNA from the scarlet (st) region of Drosophila melanogaster has been cloned by chromosome walking, using the breakpoints of a new X-ray-induced third…”
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Genomic sequences with homology to the P element of Drosophila melanogaster occur in the blowfly Lucilia cuprina
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1992)“…We have cloned two DNA elements (Lu-P1 and Lu-P2) from the Australian sheep blowfly Lucilia cuprina that are similar to the transposable P element of…”
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Immunogold localization of GyrA and GyrB proteins in Escherichia coli
Published in Microbiology (Society for General Microbiology) (01-09-1994)“…1 School of Biological Sciences, University of Manchester, UK 2 Departments of Biochemistry, University of Leicester, UK 3 Departments of Microbiology,…”
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ABC transporters involved in transport of eye pigment precursors in Drosophila melanogaster
Published in Methods in enzymology (1998)Get more information
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Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye colouration
Published in Biochimica et biophysica acta (15-07-1999)“…The white, brown and scarlet genes of Drosophila melanogaster encode proteins which transport guanine or tryptophan (precursors of the red and brown eye colour…”
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The hermit transposable element of the Australian sheep blowfly, Lucilia cuprina, belongs to the hAT family of transposable elements
Published in Genetica (01-01-1996)“…We report the cloning of hermit, a member of the hAT family of transposable elements from the genome of the Australian sheep blowfly, Lucilia cuprina. Hermit…”
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The structure, sequence and developmental pattern of expression of the white gene in the blowfly Lucilia cuprina
Published in Insect molecular biology (01-11-1996)“…We have sequenced the complete coding region of the white gene of Lucilia cuprina. Strong sequence identity exists between this gene and its homologue from…”
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Ciprofloxacin affects conformational equilibria of DNA gyrase A in the presence of magnesium ions
Published in Journal of molecular biology (03-08-2001)“…The conformational equilibria of the A subunit of DNA gyrase (GyrA), of its 59 kDa N-terminal fragment (GyrA59) and of the quinolone-resistant Ser-Trp83 mutant…”
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Locking the ATP-operated clamp of DNA gyrase: probing the mechanism of strand passage
Published in Journal of molecular biology (09-03-2001)“…DNA gyrase catalyses DNA supercoiling by passing one segment of DNA (the T segment) through another (the G segment) in a reaction coupled to the binding and…”
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Sub-cellular localisation of the white/scarlet ABC transporter to pigment granule membranes within the compound eye of Drosophila melanogaster
Published in Genetica (01-01-2000)“…The white, scarlet, and brown genes of Drosophila melanogaster encode ABC transporters involved with the uptake and storage of metabolic precursors to the red…”
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Clerocidin, a terpenoid antibiotic, inhibits bacterial DNA gyrase
Published in Journal of antibiotics (1993)Get more information
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A biochemical analysis of the interaction of DNA gyrase with the bacteriophage Mu, pSC101 and pBR322 strong gyrase sites: the role of DNA sequence in modulating gyrase supercoiling and biological activity
Published in Molecular microbiology (01-10-2003)“…Summary Replication of bacteriophage Mu DNA, a process requiring efficient synapsis of the prophage ends, takes place within the confines of the Escherichia…”
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The interaction of DNA gyrase with the bacterial toxin CcdB: evidence for the existence of two gyrase-CcdB complexes
Published in Journal of molecular biology (29-10-1999)“…CcdB is a bacterial toxin that targets DNA gyrase. Analysis of the interaction of CcdB with gyrase reveals two distinct complexes. An initial complex (alpha)…”
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Cloning and characterization of the white and topaz eye color genes from the sheep blowfly Lucilia cuprina
Published in Journal of molecular evolution (01-04-1990)“…Clones carrying the white and topaz eye color genes have been isolated from genomic DNA libraries of the blowfly Lucilia cuprina using cloned DNA from the…”
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The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription
Published in Journal of molecular biology (07-11-1997)“…We have studied the interaction of the F plasmid killer protein CcdB with its intracellular target DNA gyrase. We confirm that CcdB can induce DNA cleavage by…”
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The humoral immune response of sheep to antigens from larvae of the sheep blowfly (Lucilia cuprina)
Published in International journal for parasitology (01-08-1987)Get more information
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Characterization and chromosomal distribution of a tandemly repeated DNA sequence from the Australian sheep blowfly, Lucilia cuprina
Published in Chromosoma (01-03-1992)“…In the course of making a Lucilia cuprina genomic DNA library, a ladder of bands was seen in partial Sau3A digests. Complete digestion reduced this ladder to…”
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Molecular characterization of spontaneous mutations at the scarlet locus of Drosophila melanogaster
Published in Molecular & general genetics (20-12-1995)“…Six spontaneous mutations of the scarlet (st) locus of Drosophila melanogaster have been studied at the molecular level. Two of the mutants (st1 and stsp)…”
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