Search Results - "Howell, S. B"

Unresolved Binary Exoplanet Host Stars Fit as Single Stars: Effects on the Stellar Parameters by Furlan, E., Howell, S. B.

“…In this work, we quantify the effect of an unresolved companion star on the derived stellar parameters of the primary star if a blended spectrum is fit…”
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K2 ROTATION PERIODS FOR LOW-MASS HYADS AND THE IMPLICATIONS FOR GYROCHRONOLOGY by Douglas, S. T., Agüeros, M. A., Covey, K. R., Cargile, P. A., Barclay, T., Cody, A., Howell, S. B., Kopytova, T.

“…ABSTRACT As the closest open cluster to the Sun, the Hyades is an important benchmark for many stellar properties, but its members are also scattered widely…”
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A 38 Million Year Old Neptune-sized Planet in the Kepler Field by Bouma, L. G., Curtis, J. L., Masuda, K., Hillenbrand, L. A., Stefansson, G., Isaacson, H., Narita, N., Fukui, A., Ikoma, M., Tamura, M., Kraus, A. L., Furlan, E., Gnilka, C. L., Lester, K. V., Howell, S. B.

“…Abstract Kepler 1627A is a G8V star previously known to host a 3.8 R ⊕ planet on a 7.2 day orbit. The star was observed by the Kepler space telescope because…”
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TIC 290061484: A Triply Eclipsing Triple System with the Shortest Known Outer Period of 24.5 Days by Kostov, V. B., Rappaport, S. A., Borkovits, T., Powell, B. P., Gagliano, R., Omohundro, M., Bíró, I. B., Moe, M., Howell, S. B., Mitnyan, T., Clark, C. A., Kristiansen, M. H., Terentev, I. A., Schwengeler, H. M., Pál, A., Vanderburg, A.

“…Abstract We have discovered a triply eclipsing triple-star system, TIC 290061484, with the shortest known outer period, P out , of only 24.5 days. This…”
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The role of DNA mismatch repair in drug resistance by FINK, D, AEBI, S, HOWELL, S. B

“…Loss of DNA mismatch repair (MMR) has been observed in a variety of human cancers. In addition to predisposing to oncogenesis, loss of MMR activity is of…”
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The Ultraviolet Spectrum and Physical Properties of the Mass Donor Star in HD 226868 = Cygnus X-1 by Caballero-Nieves, S. M, Gies, D. R, Bolton, C. T, Hadrava, P, Herrero, A, Hillwig, T. C, Howell, S. B, Huang, W, Kaper, L, Koubský, P, McSwain, M. V

“…We present an examination of high-resolution, ultraviolet (UV) spectroscopy from Hubble Space Telescope of the photospheric spectrum of the O-supergiant in the…”
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Mismatch repair proficiency and in vitro response to 5-fluorouracil by Carethers ,‡, John M., Chauhan, Dharam P., Fink, Daniel, Nebel, Sibylle, Bresalier §, Robert S., Howell ,‡, Stephen B., Boland ,‡,∥, C.Richard

“…Background & Aims: The DNA mismatch repair (MMR) system recognizes certain DNA adducts caused by alkylation damage in addition to its role in recognizing and…”
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Identification of genes that mediate sensitivity to cisplatin by Niedner, H, Christen, R, Lin, X, Kondo, A, Howell, S B

“…Cisplatin (cDDP) is effective against some human tumors, but many are intrinsically resistant and, even among initially sensitive tumors, acquired resistance…”
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Stellar Wind Variations during the X-Ray High and Low States of Cygnus X-1 by Gies, D. R, Bolton, C. T, Blake, R. M, Caballero-Nieves, S. M, Crenshaw, D. M, Hadrava, P, Herrero, A, Hillwig, T. C, Howell, S. B, Huang, W, Kaper, L, Koubský, P, McSwain, M. V

“…We present results from Hubble Space Telescope ultraviolet spectroscopy of the massive X-ray and black hole binary system, HD 226868 = Cyg X-1. The spectra…”
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Cellular accumulation of the anticancer agent cisplatin: A review by GATELY, D. P, HOWELL, S. B

“…Acquired resistance to cisplatin (DDP) is a major clinical problem in the treatment of ovarian, testicular, and head and neck carcinomas; decreased…”
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The cellular pharmacology of oxaliplatin resistance by Mishima, M, Samimi, G, Kondo, A, Lin, X, Howell, S.B

“…Oxaliplatin is a third generation platinum compound that differs from cisplatin and carboplatin in having a broader spectrum of antitumour activity. Molecular…”
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Improved targeting of platinum chemotherapeutics: the antitumour activity of the HPMA copolymer platinum agent AP5280 in murine tumour models by Lin, X., Zhang, Q., Rice, J.R., Stewart, D.R., Nowotnik, D.P., Howell, S.B.

“…AP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to…”
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Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells by Pietras, R J, Fendly, B M, Chazin, V R, Pegram, M D, Howell, S B, Slamon, D J

“…Approximately 30% of human breast and ovarian cancers have amplification and/or overexpression of HER-2/neu gene which encodes a cell surface growth-factor…”
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A novel approach for combining the use of in vitro and in vivo data to measure and detect emerging moxidectin resistance in gastrointestinal nematodes of goats by Kaplan, R.M., Vidyashankar, A.N., Howell, S.B., Neiss, J.M., Williamson, L.H., Terrill, T.H.

“…Ivermectin and moxidectin are closely related avermectin/milbemycin anthelmintics and available data suggest that side resistance occurs with these two drugs…”
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A Randomized Controlled Trial Comparing Intrathecal Sustained-release Cytarabine (DepoCyt) to Intrathecal Methotrexate in Patients with Neoplastic Meningitis from Solid Tumors by GLANTZ, M. J, JAECKLE, K. A, HOWELL, S. B, CHAMBERLAIN, M. C, PHUPHANICH, S, RECHT, L, SWINNEN, L. J, MARIA, B, LAFOLLETTE, S, SCHUMANN, G. B, COLE, B. F

“…Standard treatment for neoplastic meningitis requires frequent intrathecal (IT) injections of chemotherapy and is only modestly effective. DepoCyt is a…”
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Taming the Invisible Monster: System Parameter Constraints for Aurigae from the Far-ultraviolet to the Mid-infrared by Hoard, D. W, Howell, S. B, Stencel, R. E

“…We have assembled new Spitzer Space Telescope IRAC observations of the mysterious binary star {epsilon} Aurigae, along with archival far-ultraviolet to…”
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The role of DNA mismatch repair in platinum drug resistance by FINK, D, NEBEL, S, AEBI, S, ZHENG, H, CENNI, B, NEHME, A, CHRISTEN, R. D, HOWELL, S. B

“…Loss of DNA mismatch repair occurs in many types of tumors. The effect of the loss of DNA mismatch repair activity on sensitivity to cisplatin and a panel of…”
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A near-infrared spectroscopic search for very-low-mass cool companions to notable DA white dwarfs by Dobbie, P. D., Burleigh, M. R., Levan, A. J., Barstow, M. A., Napiwotzki, R., Holberg, J. B., Hubeny, I., Howell, S. B.

“…We have undertaken a detailed near-infrared spectroscopic analysis of eight notable white dwarfs, predominantly of southern declination. In each case the…”
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Resistance to cytotoxic drugs in DNA mismatch repair-deficient cells by AEBI, S, FINK, D, GORDON, R, HEUNG KI KIM, ZHENG, H, FINK, J. L, HOWELL, S. B

“…Loss of DNA mismatch repair is a common finding in many types of sporadic human cancers as well as in tumors arising in patients with hereditary nonpolyposis…”
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Randomized Trial of a Slow-Release Versus a Standard Formulation of Cytarabine for the Intrathecal Treatment of Lymphomatous Meningitis by GLANTZ, M. J, LAFOLLETTE, S, LYTER, D, CHAMBERLAIN, M, MARIA, B. L, SCHIFFER, C, BASHIR, R, THOMAS, D, COWENS, W, HOWELL, S. B, JAECKLE, K. A, SHAPIRO, W, SWINNEN, L, ROZENTAL, J. R, PHUPHANICH, S, ROGERS, L. R, GUTHEIL, J. C, BATCHELOR, T

“…To evaluate the efficacy and safety of a slow-release formulation of cytarabine (DepoCyt; Chiron Corp, Emeryville, CA, and Skye Pharma, Inc, San Diego, CA)…”
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