Search Results - "Howell, Kelly"
-
1
Morphological Diversity of C. elegans Sensory Cilia Instructed by the Differential Expression of an Immunoglobulin Domain Protein
Published in Current biology (19-06-2017)“…Cilia on dendritic endings of sensory neurons organize distinct types of sensory machinery [1]. Ciliated endings display neuron-type-specific patterns of…”
Get full text
Journal Article -
2
Advances and limitations for the treatment of spinal muscular atrophy
Published in BMC pediatrics (03-11-2022)“…Spinal muscular atrophy (5q-SMA; SMA), a genetic neuromuscular condition affecting spinal motor neurons, is caused by defects in both copies of the SMN1 gene…”
Get full text
Journal Article -
3
Specific inhibition of myostatin activation is beneficial in mouse models of SMA therapy
Published in Human molecular genetics (01-04-2019)“…Abstract Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by loss of α-motor neurons, leading to profound skeletal muscle atrophy…”
Get full text
Journal Article -
4
ADAR1 RNA Deaminase Limits Short Interfering RNA Efficacy in Mammalian Cells
Published in The Journal of biological chemistry (04-02-2005)“…Double-stranded RNA induces the homology-dependent degradation of cognate mRNA in the cytoplasm via RNA interference (RNAi) but also is a target for…”
Get full text
Journal Article -
5
Issues in the development of a research and education framework for one health
Published in Emerging infectious diseases (01-03-2013)Get full text
Journal Article -
6
Arbovirus Diseases, Southeastern United States
Published in Emerging infectious diseases (01-11-2013)Get full text
Journal Article -
7
Small Immunoglobulin Domain Proteins at Synapses and the Maintenance of Neuronal Features
Published in Neuron (Cambridge, Mass.) (20-01-2016)“…The integrity of neural circuits must be maintained throughout the lifetime of an organism. In this issue of Neuron, Cherra and Jin (2016) characterize a…”
Get full text
Journal Article -
8
Spatiotemporal control of a novel synaptic organizer molecule
Published in Nature (London) (02-07-2015)“…Neuronal synapses need to be formed at the right time and the right place during nervous system development; here, three gene-regulatory factors (the UNC-30,…”
Get full text
Journal Article -
9
A Neurotransmitter Atlas of the Caenorhabditis elegans Male Nervous System Reveals Sexually Dimorphic Neurotransmitter Usage
Published in Genetics (Austin) (01-07-2017)“…The nervous system of most animals is sexually dimorphic but such dimorphisms are generally poorly mapped on an anatomical, cellular, and molecular level. The…”
Get full text
Journal Article -
10
Maturational and adaptive modulation of left ventricular torsional biomechanics : Doppler tissue imaging observation from infancy to adulthood
Published in Circulation (New York, N.Y.) (30-05-2006)“…Left ventricular (LV) torsional deformation, based in part on the helical myocardial fiber architecture, is an important component of LV systolic and diastolic…”
Get full text
Journal Article -
11
Notch and Ras promote sequential steps of excretory tube development in C. elegans
Published in Development (Cambridge) (15-08-2011)“…Receptor tyrosine kinases and Notch are crucial for tube formation and branching morphogenesis in many systems, but the specific cellular processes that…”
Get full text
Journal Article -
12
Identifying Biomarkers of Spinal Muscular Atrophy for Further Development
Published in Journal of neuromuscular diseases (01-01-2023)“…Spinal muscular atrophy (SMA) is caused by bi-allelic, recessive mutations of the survival motor neuron 1 (SMN1) gene and reduced expression levels of the…”
Get more information
Journal Article -
13
Spinal Muscular Atrophy: Huge Steps
Published in Cerebrum (New York, NY) (01-03-2019)“…Spinal muscular atrophy is the number one genetic cause of infant death. Until recently, half the babies born with it would die before their second birthdays,…”
Get full text
Journal Article -
14
EOR-2 is an obligate binding partner of the BTB-zinc finger protein EOR-1 in Caenorhabditis elegans
Published in Genetics (Austin) (01-04-2010)“…BTB-zinc finger transcription factors play many important roles in metazoan development. In these proteins, the BTB domain is critical for dimerization and for…”
Get full text
Journal Article -
15
The United Nations Force Intervention Brigade: Peace enforcement as a conflict management strategy in the Democratic Republic of the Congo
Published 01-01-2015“…This research explores developments within the United Nations that have led to the creation of the Forward Intervention Brigade (FIB). It will consider the…”
Get full text
Dissertation -
16
Quasi-global and regional water vapor and rainfall rate climatologies for a 35 month period
Published 2010“…Atmospheric water vapor and rainfall are crucial elements in the global water cycle. The spatial and temporal variations of total precipitable water (TPW) and…”
Get full text
Dissertation -
17
EOR-2 is an obligate binding partner of the BTB-zinc finger protein and putative ERK target EOR-1
Published 01-01-2010“…BTB-zinc finger transcription factors play many important roles in metazoan development. The BTB domain of these proteins is critical for self-association and…”
Get full text
Dissertation -
18
Vaccine storage practices in primary care physician offices: Assessment and intervention
Published in American journal of preventive medicine (01-11-2002)“…To assess the proportion of primary care physician (PCP) offices meeting vaccine storage guidelines, identify factors associated with low compliance, and…”
Get full text
Journal Article -
19
Vaccine storage practices in primary care physician offices
Published in American journal of preventive medicine (01-11-2002)Get full text
Journal Article -
20
EOR-2 is an obligate binding partner of the BTB-zinc finger protein and putative ERK target EOR-1
Get full text
Dissertation