Search Results - "Howell, F."
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Biopolymers codelivering engineered T cells and STING agonists can eliminate heterogeneous tumors
Published in The Journal of clinical investigation (01-06-2017)“…Therapies using T cells that are programmed to express chimeric antigen receptors (CAR T cells) consistently produce positive results in patients with…”
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In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers
Published in Nature nanotechnology (01-08-2017)“…An emerging approach for treating cancer involves programming patient-derived T cells with genes encoding disease-specific chimeric antigen receptors (CARs),…”
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3
Pleistocene Homo sapiens from Middle Awash, Ethiopia
Published in Nature (London) (12-06-2003)“…The origin of anatomically modern Homo sapiens and the fate of Neanderthals have been fundamental questions in human evolutionary studies for over a century. A…”
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Macrovertebrate Paleontology and the Pliocene Habitat of Ardipithecus ramidus
Published in Science (American Association for the Advancement of Science) (02-10-2009)“…A diverse assemblage of large mammals is spatially and stratigraphically associated with Ardipithecus ramidus at Aramis. The most common species are…”
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Practical challenges in hybrid simulation studies interfacing transient stability and electro-magnetic transient simulations
Published in Electric power systems research (01-01-2021)“…•The challenges in using FDNE and multi-port Thevenin equivalent in hybrid simulation studies with real-time simulators are discussed.•The common causes of…”
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6
MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells
Published in PloS one (08-03-2011)“…Chronic lymphocytic leukemia (CLL) is thought to be a disease of resting lymphocytes. However, recent data suggest that CLL cells may more closely resemble…”
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Asa Issie, Aramis and the origin of Australopithecus
Published in Nature (13-04-2006)“…The origin of Australopithecus, the genus widely interpreted as ancestral to Homo, is a central problem in human evolutionary studies. Australopithecus species…”
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8
B cells engineered to express pathogen-specific antibodies protect against infection
Published in Science immunology (17-05-2019)“…Effective vaccines inducing lifelong protection against many important infections such as respiratory syncytial virus (RSV), HIV, influenza virus, and…”
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The microRNA miR-31 inhibits CD8+ T cell function in chronic viral infection
Published in Nature immunology (01-07-2017)“…Wucherpfennig and colleagues show that the microRNA miR-31 increases the sensitivity of T cells to type I interferons, which interferes with effector T cell…”
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Reductions in tobacco smoke pollution and increases in support for smoke-free public places following the implementation of comprehensive smoke-free workplace legislation in the Republic of Ireland: findings from the ITC Ireland/UK Survey
Published in Tobacco control (01-06-2006)“…Objective: To evaluate the psychosocial and behavioural impact of the first ever national level comprehensive workplace smoke-free law, implemented in Ireland…”
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11
Smoke-free bars in Ireland: a runaway success
Published in Tobacco control (01-04-2005)“…Ireland is not alone in having smoke-free bars. Since March 2004, Norway, New Zealand, Uganda, Bhutan, and Italy, have implemented smoke-free workplace…”
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12
Macrovertebrate Paleontology and the Pliocene Habitat of Ardipithecus ramidus
Published in Science (American Association for the Advancement of Science) (02-10-2009)“…A diverse assemblage of large mammals is spatially and stratigraphically associated with Ardipithecus ramidus at Aramis. The most common species are…”
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13
Occurrence of Theropithecus sp. in the Late Villafranchian of Southern Italy and implication for Early Pleistocene “out of Africa” dispersals
Published in Journal of human evolution (01-10-2004)“…Three cervical vertebrae of a large primate have been identified in the revision of the faunal assemblage collected during the late '70s from fissure fillings…”
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14
Not miR-ly small RNAs: Big potential for microRNAs in therapy
Published in Journal of allergy and clinical immunology (01-02-2008)“…RNA interference (RNAi) describes a set of natural processes in which genes are silenced by small RNAs. RNAi has been widely used as an experimental tool that…”
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15
Safety switch optimization enhances antibody-mediated elimination of CAR T cells
Published in Frontiers in Molecular Medicine (11-10-2022)“…Activation of a conditional safety switch has the potential to reverse serious toxicities arising from the administration of engineered cellular therapies,…”
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Spectrum of infection and risk factors for human monkeypox, United States, 2003
Published in Emerging infectious diseases (01-09-2007)“…For the 2003 monkeypox virus (MPXV) outbreak in the United States, interhuman transmission was not documented and all case-patients were near or handled…”
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The Lower Pleistocene lithic assemblage from Dursunlu (Konya), central Anatolia, Turkey
Published in Antiquity (01-03-2009)“…Homo erectus leaving Africa a million years ago ought to have passed through the area that is now Turkey, and the authors report a first certain sighting of…”
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18
Generation rescheduling methods to improve power transfer capability constrained by small-signal stability
Published in IEEE transactions on power systems (01-02-2004)“…Small-signal stability, often in the form of low frequency oscillations, has been found to be the limiting factor when determining power transfer capabilities…”
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Relation of tissue Doppler derived myocardial velocities to myocardial structure and beta-adrenergic receptor density in humans
Published in Journal of the American College of Cardiology (01-09-2000)“…OBJECTIVES We sought to evaluate the relation of segmental tissue Doppler (TD) velocities to both the regional amount of interstitial fibrosis and the myocyte…”
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Mandibular postcanine dentition from the Shungura Formation, Ethiopia: Crown morphology, taxonomic allocations, and Plio-Pleistocene hominid evolution
Published in American journal of physical anthropology (01-10-1996)“…Over 200 hominid specimens were recovered by the International Omo Expedition of 1967–1976. Despite the fragmentary nature of this primarily dental collection,…”
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