Search Results - "Howell, D.S."

Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization by Leroux, M.A., Cheung, H.S., Bau, J.L., Wang, J.Y., Howell, D.S., Setton, L.A.

“…Joint immobilization is associated with altered cartilage biosynthesis and catabolism that may affect cartilage mechanics and joint function. In this study,…”
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Pyridoxine deficiency affects biomechanical properties of chick tibial bone by Massé, P.G., Rimnac, C.M., Yamauchi, M., Coburn, S.P., Rucker, R.B., Howell, D.S., Boskey, A.L.

“…The mechanical integrity of bone is dependent on the bone matrix, which is believed to account for the plastic deformation of the tissue, and the mineral,…”
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Bone Metabolic Imbalance Occurs at an Early Stage of Natural Menopause by Masse, P.G., Dosy, J., Jougleux, J.L., Donovan, S.M., Caissie, M., Howell, D.S.

“…The present study was aimed to clarify whether bone uncoupling occurs in early (3-5 years) natural menopause. Plasma bone specific alkaline phosphatase (bALP)…”
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Hepatocyte growth factor and its actions in growth plate chondrocytes by Grumbles, R.M., Howell, D.S., Wenger, L., Altman, R.D., Howard, G.A., Roos, B.A.

“…Hepatocyte growth factor (HGF) has been implicated as a paracrine regulator of organogenesis and repair in many tissues. Here we have studied the expression…”
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Effects of vitamin D metabolites on healing of low phosphate, vitamin D-deficient induced rickets in rats by Atkin, I, Pita, J C, Ornoy, A, Agundez, A, Castiglione, G, Howell, D S

“…A model of low-phosphate, vitamin D-deficient rachitic rats was used to compare the effects of 1 alpha(OH)D3, 1,25(OH)2D3, and 24,25(OH)2D3 on cartilage and…”
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Aspiration and characterization of predentin fluid in developing rat teeth by means of a micropuncture and micro-analytical technique by Larsson, P A, Howell, D S, Pita, J C, Blanco, L N

“…A fluid phase was aspirated in vivo and in vitro from predentin or pulp of developing rat teeth by means of a micropuncture technique. Pooled aspirates…”
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Basic calcium phosphate crystals up-regulate metalloproteinases but down-regulate tissue inhibitor of metalloproteinase-1 and -2 in human fibroblasts by Bai, G., Howell, D.S., Howard, G.A., Roos, B.A., Cheung, H.S.

“…Objective To examine the effect of basic calcium phosphate (BCP) crystals on expression of tissue inhibitors of metalloproteinases (TIMP)-1 and -2 in human…”
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Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D3, interleukin-1β, and okadaic acid by Grumbles, R.M., Shao, L., Jeffrey, J.J., Howell, D.S.

“…The interstitial collagenase produced by the rat growth plate chondrocytes is the homologue of the human collagenase‐3, or matrix metalloproteinase‐13. This…”
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Quantitative Polymerase Chain Reaction Assay for Aggrecan and Link Protein Gene Expression in Cartilage by Re, P., Valhmu, W.B., Vostrejs, M., Howell, D.S., Fischer, S.G., Ratcliffe, A.

“…A procedure has been developed to quantify the levels of aggrecan and link protein mRNAs in small amounts of various tissues, including cartilage, using the…”
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Regulation of the rat interstitial collagenase promoter by IL-1β, c-Jun, and ras-dependent signaling in growth plate chondrocytes by Grumbles, R.M., Shao, L., Jeffrey, J.J., Howell, D.S.

“…In an attempt to better define molecular influences on rat interstitial collagenase gene expression in cartilage, the promoter function was characterized using…”
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A cartilage matrix deficiency experimentally induced by vitamin B6 deficiency by Massé, P G, Ziv, I, Cole, D E, Mahuren, J D, Donovan, S M, Yamauchi, M, Howell, D S

“…A vitamin B6-deficiency-induced disorder in avian articular cartilage resembling osteoarthritis has been further characterized. We measured several parameters…”
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Characterization of the metalloproteinase inhibitor produced by bovine articular chondrocyte cultures by Morales, T I, Kuettner, K E, Howell, D S, Woessner, J F

“…Primary cultures of bovine articular chondrocytes release a latent metalloproteinase which is activated by incubation with organomercurials to degrade…”
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Alterations in the composition of growth cartilage septa during calcification studied by microscopic x-ray elemental analysis by Howell, D S, Carlson, L

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SULFUR METABOLISM IN CARTILAGE. A STUDY OF CALCIFYING REGIONS FOR MICROSCOPIC DISTRIBUTION OF SULFUR AND RELATIONSHIP TO STAINING BY SUDAN BLACK by HOWELL, D S, CARLSON, L

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THE EFFECT OF PAPAIN ON MINERAL DEPOSITION IN THE HEALING OF RACHITIC EPIPHYSES by HOWELL, D S, CARLSON, L

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