Search Results - "Howdle, S. M."

A comparison of polymer and polymer-hydroxyapatite composite tissue engineered scaffolds for use in bone regeneration. An in vitro and in vivo study by Tayton, E., Purcell, M., Aarvold, A., Smith, J. O., Briscoe, A., Kanczler, J. M., Shakesheff, K. M., Howdle, S. M., Dunlop, D. G., Oreffo, R. O. C.

“…Previous in vitro work demonstrated porous PLA and PLGA both had the mechanical strength and sustained the excellent skeletal stem cell (SSC) growth required…”
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Sustained release hGH microsphere formulation produced by a novel supercritical fluid technology: In vivo studies by Jordan, F., Naylor, A., Kelly, C.A., Howdle, S.M., Lewis, A., Illum, L.

“…Novel sustained release formulations of hGH prepared by supercritical fluid processing of PLGA/PLA (the CriticalMix™ process) were produced in the form of…”
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Novel green route towards polyesters-based resin by photopolymerization of star polymers by Baheti, P., Bonneaud, C., Bouilhac, C., Joly-Duhamel, C., Howdle, S. M., Lacroix-Desmazes, P.

“…Bio-based star-shaped poly(ε-caprolactone)s (S-PCL) derived from sugar-based D-sorbitol as an initiator were obtained via solvent-free enzymatic ring-opening…”
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Growth factor release from tissue engineering scaffolds by Whitaker, M. J., Quirk, R. A., Howdle, S. M., Shakesheff, K. M.

“…Synthetic scaffold materials are used in tissue engineering for a variety of applications, including physical supports for the creation of functional tissues,…”
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Surface-Enhanced Raman Scattering Using Microstructured Optical Fiber Substrates by Amezcua-Correa, A., Yang, J., Finlayson, C. E., Peacock, A. C., Hayes, J. R., Sazio, P. J. A., Baumberg, J. J., Howdle, S. M.

“…Microstructured optical fibers (MOFs) represent a promising platform technology for fully integrated next generation surface enhanced Raman scattering (SERS)…”
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Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification by Yang, X.B., Roach, H.I., Clarke, N.M.P., Howdle, S.M., Quirk, R., Shakesheff, K.M., Oreffo, R.O.C.

“…The ability to generate new bone for skeletal use is a major clinical need. Biomimetic scaffolds that interact and promote osteoblast differentiation and…”
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Using Plasma Deposits to Promote Cell Population of the Porous Interior of Three-Dimensional Poly(D,L-Lactic Acid) Tissue-Engineering Scaffolds by Barry, J. J. A., Silva, M. M. C. G., Shakesheff, K. M., Howdle, S. M., Alexander, M. R.

“…Cell adhesion and proliferation on poly(D,L‐lactic acid) (PDLLA) tissue‐engineering scaffolds is low. This is generally regarded to be due to the surface…”
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Three-Dimensional Bioactive and Biodegradable Scaffolds Fabricated by Surface-Selective Laser Sintering by Antonov, E. N., Bagratashvili, V. N., Whitaker, M. J., Barry, J. J. A., Shakesheff, K. M., Konovalov, A. N., Popov, V. K., Howdle, S. M.

“…Surface‐selective laser sintering (SSLS) has been developed for fabrication of three‐dimensional polymer composite scaffolds with precise dimensions and…”
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Characterisation of microcellular foams produced from semi-crystalline PCL using supercritical carbon dioxide by Jenkins, M.J., Harrison, K.L., Silva, M.M.C.G., Whitaker, M.J., Shakesheff, K.M., Howdle, S.M.

“…Microcellular foams were produced from polycaprolactone (PCL) using a method based on the rapid release of supercritical CO 2. The average pore size in the…”
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Water-in-Carbon Dioxide Microemulsions: An Environment for Hydrophiles Including Proteins by Johnston, K. P., Harrison, K. L., Clarke, M. J., Howdle, S. M., Heitz, M. P., Bright, F. V., Carlier, C., Randolph, T. W.

“…Carbon dioxide in the liquid and supercritical fluid states is useful as a replacement for toxic organic solvents. However, nonvolatile hydrophilic substances…”
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Control of pore size and structure of tissue engineering scaffolds produced by supercritical fluid processing by Tai, Hongyun, Mather, Melissa L, Howard, Daniel, Wang, Wenxin, White, Lisa J, Crowe, John A, Morgan, Steve P, Chandra, Amit, Williams, David J, Howdle, Steven M, Shakesheff, Kevin M

“…Tissue engineering scaffolds require a controlled pore size and structure to host tissue formation. Supercritical carbon dioxide (scCO2) processing may be used…”
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The influence of dispersant concentration on the pore morphology of hydroxyapatite ceramics for bone tissue engineering by Cyster, L.A., Grant, D.M., Howdle, S.M., Rose, F.R.A.J., Irvine, D.J., Freeman, D., Scotchford, C.A., Shakesheff, K.M.

“…There is a clinical need for synthetic scaffolds that will promote bone regeneration. Important factors include obtaining an optimal porosity and size of…”
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Single shot tetanus vaccine manufactured by a supercritical fluid encapsulation technology by Baxendale, AJ, van Hooff, P., Durrant, L.G., Spendlove, I., Howdle, S.M., Woods, H.M., Whitaker, M.J., Davies, O.R., Naylor, A., Lewis, A.L., Illum, L.

“…Single shot vaccines of tetanus toxoid (TT) were manufactured using the NanoMix™ process – a low temperature solvent free encapsulation technology using…”
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Porous methacrylate scaffolds: supercritical fluid fabrication and in vitro chondrocyte responses by Barry, J.J.A., Gidda, H.S., Scotchford, C.A., Howdle, S.M.

“…This paper describes a method of foaming a polymer system comprising poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEMA/THFMA), characterisation of…”
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Laser stereolithography and supercritical fluid processing for custom-designed implant fabrication by Popov, V K, Evseev, A V, Ivanov, A L, Roginski, V V, Volozhin, A I, Howdle, S M

“…This paper describes the laser photopolymerization of a liquid mixture of polyfunctional acrylic monomers, photoinitiator and hydroxyapatite (HA). Pure…”
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Fluorinated Graft Stabilizers for Polymerization in Supercritical Carbon Dioxide:  The Effect of Stabilizer Architecture by Giles, M. R, Griffiths, R. M. T, Aguiar-Ricardo, A, Silva, M. M. C. G, Howdle, S. M

“…We describe the synthesis of new stabilizers for the free radical polymerization of methyl methacrylate in supercritical carbon dioxide. The stabilizers are…”
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High-pressure rheological analysis of CO2-induced melting point depression and viscosity reduction of poly(ε-caprolactone) by Curia, S., De Focatiis, D.S.A., Howdle, S.M.

“…High-pressure rheology has been used to assess the effects of supercritical carbon dioxide (scCO2) on the melting point (Tm) and viscosity of…”
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Novel Nanostructured Polymeric Composites of Polycaprolactone and Ultra-High Molecular Weight Polyethylene via a Supercritical-Fluid Route by Busby, A. J., Zhang, J., Roberts, C. J., Lester, E., Howdle, S. M.

“…A supercritical‐fluid process for creating blends of ultra‐high‐molecular‐weight polyethylene and biodegradable polycaprolactone is described. These are…”
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Can Supercritical Carbon Dioxide Improve the Mechanical Integrity of Ultrahigh-Molecular-Weight Polyethylene? by Naylor, A., Timashev, P. S., Solov'eva, A. B., Erina, N. A., Kotova, S., Busby, A. J., Popov, V. K., Howdle, S. M.

“…A novel ultrahigh‐molecular‐weight polyethylene/polymethacrylate semi‐ interpenetrating network is prepared using supercritical CO2. The mechanical properties…”
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Interconnectivity and permeability of supercritical fluid-foamed scaffolds and the effect of their structural properties on cell distribution by Reinwald, Y, Johal, R K, Ghaemmaghami, A M, Rose, F RAJ, Howdle, S M, Shakesheff, K M

“…This study aims to investigate interconnectivity and permeability of scCO sub(2)-foamed scaffolds and the influence of structural scaffold properties on cell…”
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