Search Results - "Howdle, P. D."

Evidence of high sugar intake, and low fibre and mineral intake, in the gluten‐free diet by Wild, D., Robins, G. G., Burley, V. J., Howdle, P. D.

“…Aliment Pharmacol Ther 2010; 32: 573–581 Summary Background  The only therapy for coeliac disease (CD) is a long‐term gluten‐free diet (GFD). Little is known…”
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Neurologic complications of liver transplantation in adults by LEWIS, M. B, HOWDLE, P. D

“…To describe the incidence and nature of neurologic complications following liver transplantation. Adult patients who received liver transplants at St. James's…”
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Primary small‐bowel malignancy in the UK and its association with coeliac disease by Howdle, P.D., Jalal, P.K., Holmes, G.K.T., Houlston, R.S.

“…Background: Malignancies of the small intestine are rare, accounting for <2% of all cancers of the gastrointestinal tract. There is little information about…”
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Long-term histological follow-up of people with coeliac disease in a UK teaching hospital by Hutchinson, J.M., West, N.P., Robins, G.G., Howdle, P.D.

“…Background: Coeliac disease is a relatively common condition which is usually managed by placing patients on a gluten free diet. Follow up biopsies to confirm…”
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The neurology of liver failure by Lewis, M., Howdle, P.D.

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Is a raised intraepithelial lymphocyte count with normal duodenal villous architecture clinically relevant? by Mahadeva, S, Wyatt, J I, Howdle, P D

“…Background: A raised intraepithelial lymphocyte (IEL) count with normal villous architecture is a recognised finding in latent coeliac disease. Little…”
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Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers by Haan, J.C., Buffart, T.E., Eijk, P.P., van de Wiel, M.A., van Wieringen, W.N., Howdle, P.D., Mulder, C.J.J., van de Velde, C.J., Quirke, P., Nagtegaal, I.D., van Grieken, N.C.T., Grabsch, H., Meijer, G.A., Ylstra, B.

“…Small bowel adenocarcinoma (SBA) is a rare cancer and consequently, the options for clinical trials are limited. As they are treated according to either a…”
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Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction by Goode, Helen F, Cowley, Hugh C, Walker, Barry E, Howdle, Peter D, Webster, Nigel R

“…OBJECTIVETo determine antioxidant vitamin concentrations, lipid peroxidation, and an index of nitric oxide production in patients in the intensive care unit…”
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Contribution of the MHC region to the familial risk of coeliac disease by Bevan, S, Popat, S, Braegger, C P, Busch, A, O’Donoghue, D, Falth-Magnusson, K, Ferguson, A, Godkin, A, Hogberg, L, Holmes, G, Hosie, K B, Howdle, P D, Jenkins, H, Jewell, D, Johnston, S, Kennedy, N P, Kerr, G, Kumar, P, Logan, R F A, Love, A H G, Marsh, M, Mulder, C J J, Sjoberg, K, Stenhammer, L, Walker-Smith, J, Marossy, A M, Houlston, R S

“…Susceptibility to coeliac disease is genetically determined by possession of specific HLA-DQ alleles, acting in concert with one or more non-HLA linked genes…”
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Systemic cytomegalovirus infection complicating ulcerative colitis: a case report and review of the literature by Hamlin, P J, Shah, M N, Scott, N, Wyatt, J I, Howdle, P D

“…Cytomegalovirus is a common infection worldwide and in the immunocompromised individual it can be a major cause of morbidity and mortality. In patients with…”
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Advances in celiac disease by Robins, G, Howdle, P D

“…PURPOSE OF REVIEWThis article aims to summarize recent critical research in celiac disease. RECENT FINDINGSThe crucial epitopes that confer toxicity to gliadin…”
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Review article: management of patients with non-responsive coeliac disease by O'Mahony, S, Howdle, P D, Losowsky, M S

“…A substantial minority of patients with coeliac disease (estimated at anything between 7 and 30%) fail to respond to treatment with a gluten-free diet…”
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Combination oral antioxidant supplementation reduces blood pressure by Galley, H F, Thornton, J, Howdle, P D, Walker, B E, Webster, N R

“…1. Hypertension affects 30% of adults and low intakes of antioxidants have been associated with increased risk of hypertension and cardiovascular disease. To…”
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Linkage Analysis of Candidate Regions for Coeliac Disease Genes by Houlston, R. S., Tomlinson, I. P. M., Ford, D., Seal, S., Marossy, A. M., Ferguson, A., Holmes, G. K. T., Hosie, K. B., Howdle, P. D., Jewell, D. P., Godkin, A., Kerr, G. D., Kumar, P., Logan, R. F. A., Love, A. H. G., Johnston, S., Marsh, M. N., Mitton, S., O'Donoghue, D., Roberts, A., Walker-Smith, J. A., Stratton, M. F.

“…A strong HLA association is seen in coeliac disease [specifically to the DQ(α1*0501,β1*0201 heterodimer], but this cannot entirely account for the increased…”
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Mycobacterium paratuberculosis DNA not detected in Crohn's disease tissue by fluorescent polymerase chain reaction by Rowbotham, D S, Mapstone, N P, Trejdosiewicz, L K, Howdle, P D, Quirke, P

“…The role of mycobacteria in the aetiology of Crohn's disease has been a contentious subject for many years. Mycobacterium paratuberculosis is known to cause a…”
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Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease by POPAT, S., HEARLE, N., HOGBERG, L., BRAEGGER, C. P., O'DONOGHUE, D., FALTH-MAGNUSSON, K., HOLMES, G. K. T., HOWDLE, P. D., JENKINS, H., JOHNSTON, S., KENNEDY, N. P., KUMAR, P. J., LOGAN, R. F. A., MARSH, M. N., MULDER, C. J., TORINSSON NALUAI, A., SJOBERG, K., STENHAMMAR, L., WALTERS, J. R. F., JEWELL, D. P., HOULSTON, R. S.

“…Susceptibility to coeliac disease involves HLA and non-HLA-linked genes. The CTLA4/CD28 gene region encodes immune regulatory T-cell surface molecules and is a…”
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Delayed myelopathic presentation of the acquired hepatocerebral degeneration syndrome by LEWIS, M. B, MACQUILLAN, G, BAMFORD, J. M, HOWDLE, P. D

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Genome screening of coeliac disease by Popat, S, Bevan, S, Braegger, C P, Busch, A, O'Donoghue, D, Falth-Magnusson, K, Godkin, A, Hogberg, L, Holmes, G, Hosie, K B, Howdle, P D, Jenkins, H, Jewell, D, Johnston, S, Kennedy, N P, Kumar, P, Logan, R F A, Love, A H G, Marsh, M N, Mulder, C J, Sjoberg, K, Stenhammar, L, Walker-Smith, J, Houlston, R S

“…2- 4 Evidence for an inherited predisposition to coeliac disease comes from studies of first degree relatives of patients and studies of twins. 5, 6 A strong…”
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Small bowel malignancy in coeliac disease by Howdle, P D, Holmes, G K T

“…The findings are very much in accord with ours from the British Society of Gastroenterology (BSG) National UK Survey published earlier this year. 1 Over a two…”
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Teaching in the new NHS: the specialised ward based teacher by Kilminster, S M, Delmotte, A, Frith, H, Jolly, B C, Stark, P, Howdle, P D

“…Objectives To evaluate the effects of introducing specialised ward based teachers (WBTs) who had a broad remit to improve third year medical undergraduates’…”
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