Properties of Proxy-Derived Modified Rankin Scale Assessment

Background Cognitive or communication issues may preclude direct modified Rankin Scale interview, necessitating interview with a suitable surrogate. The clinimetric properties of this proxy modified Rankin Scale assessment have not been described. Aims To describe reliability of proxy-derived modifi...

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Bibliographic Details
Published in:	International journal of stroke Vol. 8; no. 6; pp. 403 - 407
Main Authors:	McArthur, Kate, Beagan, Michael L. C., Degnan, Andrew, Howarth, Rosanne C., Mitchell, Kirsten A., McQuaige, Fiona B., Shannon, Mary Ann C., Stott, DJ, Quinn, Terence J.
Format:	Journal Article
Language:	English
Published:	London, England SAGE Publications 01-08-2013 Sage Publications Ltd
Subjects:	Aged Aged, 80 and over clinimetrics disability Female Humans Male modified Rankin Scale Neurologic Examination - methods Observer Variation outcomes Proxy Recovery of Function scales stroke Stroke - complications Stroke - diagnosis clinimetrics modified Rankin Scale outcomes stroke disability scales
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Summary:	Background Cognitive or communication issues may preclude direct modified Rankin Scale interview, necessitating interview with a suitable surrogate. The clinimetric properties of this proxy modified Rankin Scale assessment have not been described. Aims To describe reliability of proxy-derived modified Rankin Scale and compare with traditional direct patient interview. Methods Researchers assessed consenting stroke inpatients and their proxies using a nonstructured modified Rankin Scale approach. Paired interviewers (trained in modified Rankin Scale) performed independent and blinded modified Rankin Scale assessment of patients and appropriate proxies. Interobserver variability and agreement between patient and proxy modified Rankin Scale were described using kappa statistics (k, 95% confidence interval) and percentage agreement. Results Ninety-seven stroke survivors were assessed. Proxies were family members (n = 29), nurses (n = 50), or physiotherapists (n = 25). Median modified Rankin Scale from both patient and proxies was 3 [interquartile range (IQR): 2–4]. Reliability for patient modified Rankin Scale interview was weighted kappa = 0.70 (95% confidence interval: 0.30–1.00). Reliability for proxy modified Rankin Scale weighted kappa = 0.62 (95% confidence interval: 0.34–0.90). Subgroup analysis of various proxy information sources were as follows: family weighted kappa = 0.61; nurse weighted kappa = 0.58; therapist weighted kappa = 0.58. There was disagreement between patient-derived modified Rankin Scale and corresponding proxy modified Rankin Scale weighted kappa = 0.64 (95% CI: 0.42–0.86). Conclusions There is potential for substantial interobserver variability in proxy modified Rankin Scale and validity of certain proxy assessments is questionable. Direct modified Rankin Scale interview is preferred.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	1747-4930 1747-4949
DOI:	10.1111/j.1747-4949.2011.00759.x