Search Results - "Howard, Sean M."

Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes by Ranjha, Lepakshi, Howard, Sean M., Cejka, Petr

“…DNA double-strand breaks arise accidentally upon exposure of DNA to radiation and chemicals or result from faulty DNA metabolic processes. DNA breaks can also…”
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CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection by Ceppi, Ilaria, Howard, Sean M., Kasaciunaite, Kristina, Pinto, Cosimo, Anand, Roopesh, Seidel, Ralf, Cejka, Petr

“…To repair a DNA double-strand break by homologous recombination, 5′-terminated DNA strands must first be resected to reveal 3′- overhangs. This process is…”
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DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining by Howard, Sean M, Yanez, Diana A, Stark, Jeremy M

“…Alternative end joining (Alt-EJ) chromosomal break repair involves bypassing classical non-homologous end joining (c-NHEJ), and such repair causes mutations…”
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Phosphorylated CtIP bridges DNA to promote annealing of broken ends by Öz, Robin, Howard, Sean M., Sharma, Rajhans, Törnkvist, Hanna, Ceppi, Ilaria, KK, Sriram, Kristiansson, Erik, Cejka, Petr, Westerlund, Fredrik

“…The early steps of DNA double-strand break (DSB) repair in human cells involve the MRE11-RAD50-NBS1 (MRN) complex and its cofactor, phosphorylated CtIP. The…”
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination by Onyango, David O, Howard, Sean M, Neherin, Kashfia, Yanez, Diana A, Stark, Jeremy M

“…We examined the influence of the tetratricopeptide repeat factor XAB2 on chromosomal break repair, and found that XAB2 promotes end resection that generates…”
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Biological maturity-associated variance in peak power output and momentum in academy rugby union players by Howard, Sean M. A., Cumming, Sean P., Atkinson, Mark, Malina, Robert M.

“…The study aimed to evaluate the mediating effect of biological maturation on anthropometrical measurements, performance indicators and subsequent selection in…”
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DNA Damage Response Factors from Diverse Pathways, Including DNA Crosslink Repair, Mediate Alternative End Joining: e1004943 by Howard, Sean M, Yanez, Diana A, Stark, Jeremy M

“…Alternative end joining (Alt-EJ) chromosomal break repair involves bypassing classical non-homologous end joining (c-NHEJ), and such repair causes mutations…”
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