Search Results - "Howard, N E"

Wound healing dressings and drug delivery systems: a review by Boateng, Joshua S, Matthews, Kerr H, Stevens, Howard N E, Eccleston, Gillian M

“…The variety of wound types has resulted in a wide range of wound dressings with new products frequently introduced to target different aspects of the wound…”
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Characterisation of freeze-dried wafers and solvent evaporated films as potential drug delivery systems to mucosal surfaces by Boateng, Joshua S., Auffret, Anthony D., Matthews, Kerr H., Humphrey, Michael J., Stevens, Howard N.E., Eccleston, Gillian M.

“…Freeze-dried (lyophilised) wafers and solvent cast films from sodium alginate (ALG) and sodium carboxymethylcellulose (CMC) have been developed as potential…”
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A New Class of Safe Oligosaccharide Polymer Therapy To Modify the Mucus Barrier of Chronic Respiratory Disease by Pritchard, Manon F, Powell, Lydia C, Menzies, Georgina E, Lewis, Paul D, Hawkins, Karl, Wright, Chris, Doull, Iolo, Walsh, Timothy R, Onsøyen, Edvar, Dessen, Arne, Myrvold, Rolf, Rye, Philip D, Myrset, Astrid H, Stevens, Howard N. E, Hodges, Lee A, MacGregor, Gordon, Neilly, James B, Hill, Katja E, Thomas, David W

“…The host- and bacteria-derived extracellular polysaccharide coating of the lung is a considerable challenge in chronic respiratory disease and is a powerful…”
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In-vitro and in-vivo erosion profiles of hydroxypropylmethylcellulose (HPMC) matrix tablets by Ghimire, Manish, Hodges, Lee Ann, Band, Janet, O'Mahony, Bridget, McInnes, Fiona J., Mullen, Alexander B., Stevens, Howard N.E.

“…The purpose of this study was to evaluate and compare the in-vitro and in-vivo erosion profiles of two tablet formulations primarily consisting of…”
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Development and mechanical characterization of solvent-cast polymeric films as potential drug delivery systems to mucosal surfaces by Boateng, Joshua S., Stevens, Howard N.E., Eccleston, Gillian M., Auffret, Anthony D., Humphrey, Michael J., Matthews, Kerr H.

“…Solvent-cast films from three polymers, carboxymethylcellulose (CMC), sodium alginate (SA), and xanthan gum, were prepared by drying the polymeric gels in air…”
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Assessing gastrointestinal motility and disintegration profiles of magnetic tablets by a novel magnetic imaging device and gamma scintigraphy by Goodman, Kirsteen, Hodges, Lee Ann, Band, Janet, Stevens, Howard N.E., Weitschies, Werner, Wilson, Clive G.

“…To validate Magnetic Moment Imaging (MMI) for the investigation of gastrointestinal transit and disintegration of solid dosage forms and to correlate the MMI…”
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Correlation between in vitro and in vivo erosion behaviour of erodible tablets using gamma scintigraphy by Ghimire, Manish, Hodges, Lee Ann, Band, Janet, Lindsay, Blythe, O’Mahony, Bridget, McInnes, Fiona J., Mullen, Alexander B., Stevens, Howard N.E.

“…Effect of manufacturing methods on in vitro and in vivo erosion profiles of wax-disintegrant based matrix tablets using gamma scintigraphy. In vitro and in…”
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In-vitro/in-vivo correlation of pulsatile drug release from press-coated tablet formulations: A pharmacoscintigraphic study in the beagle dog by Ghimire, Manish, McInnes, Fiona J., Watson, David G., Mullen, Alexander B., Stevens, Howard N.E.

“…The aim of the current study was to investigate the in-vitro and in-vivo performance of a press-coated tablet (PCT) intended for time delayed drug release,…”
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Evaluation of the Clearance of a Sublingual Buprenorphine Spray in the Beagle Dog Using Gamma Scintigraphy by McInnes, Fiona, Clear, Nicola, James, Gerry, Stevens, Howard N. E., Vivanco, Unai, Humphrey, Michael

“…Purpose The aim of this study was to evaluate clearance from the buccal cavity and pharmacokinetic profiles of a sublingual spray formulation in the dog, to…”
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In Vivo Performance of an Oral MR Matrix Tablet Formulation in the Beagle Dog in the Fed and Fasted State: Assessment of Mechanical Weakness by McInnes, Fiona, Clear, Nicola, Humphrey, Michael, Stevens, Howard N E

“…Purpose To evaluate the behaviour of an oral matrix modified release formulation in the canine gastrointestinal tract, and establish if a mechanical weakness…”
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Comparison of the rates of disintegration, gastric emptying, and drug absorption following administration of a new and a conventional paracetamol formulation, using γ scintigraphy by KELLY, Kilian, O'MAHONY, Bridget, LINDSAY, Blythe, JONES, Tamara, GRATTAN, Tim J, ROSTAMI-HODJEGAN, Amin, STEVENS, Howard N. E, WILSON, Clive G

“…To investigate the hypothesis that faster drug absorption from a new paracetamol formulation containing sodium bicarbonate compared to that from a conventional…”
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Nasal residence of insulin containing lyophilised nasal insert formulations, using gamma scintigraphy by McInnes, Fiona J., O’Mahony, Bridget, Lindsay, Blythe, Band, Janet, Wilson, Clive G., Hodges, Lee Ann, Stevens, Howard N.E.

“…Bioadhesive dosage forms are a potential method for overcoming rapid mucociliary transport in the nose. A lyophilised nasal insert formulation previously…”
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A pharmacoscintigraphic study of three time-delayed capsule formulations in healthy male volunteers by McConville, Jason T, Hodges, Lee-Ann, Jones, Tamara, Band, Janet P, O'Mahony, Bridget, Lindsay, Blythe, Ross, Alistair C, Florence, Alastair J, Stanley, Adrian J, Humphrey, Michael J, Wilson, Clive G, Stevens, Howard N E

“…Three time-delayed capsule (TDC) formulations were investigated in a pharmacoscintigraphic study, using a three-way crossover design in eight healthy male…”
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Does human immunodeficiency virus status affect early wound healing in open surgically stabilised tibial fractures?: A prospective study by Howard, N E, Phaff, M, Aird, J, Wicks, L, Rollinson, P

“…We compared early post-operative rates of wound infection in HIV-positive and -negative patients presenting with open tibial fractures managed with surgical…”
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The use of simple dynamic mucosal models and confocal microscopy for the evaluation of lyophilised nasal formulations by McInnes, Fiona, Baillie, Alan J., Stevens, Howard N. E.

“…A range of methods is reported in the literature for assessing hydration and adhesion parameters in the performance of nasal bioadhesive formulations; however,…”
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Days and Nights on the Internet: The Impact of a Diffusing Technology by HOWARD, PHILIP E. N., RAINIE, LEE, JONES, STEVE

“…For a growing cohort of Americans, Internet tools have become a significant conduit of social life and work life. The surveys of the Pew Internet & American…”
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In vivo evaluation of nicotine lyophilised nasal insert in sheep by McInnes, Fiona J., Thapa, Panna, Baillie, Alan J., Welling, Peter G., Watson, David G., Gibson, Ian, Nolan, Andrea, Stevens, Howard N.E.

“…The nasal route offers an attractive means of delivering a drug directly to the systemic circulation and avoiding hepatic first-pass metabolism, although rapid…”
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Evaluation of Pulsincap™ to provide regional delivery of dofetilide to the human GI tract by Stevens, Howard N.E, Wilson, Clive G, Welling, Peter G, Bakhshaee, Massoud, Binns, Julie S, Perkins, Alan C, Frier, Malcolm, Blackshaw, Elaine P, Frame, Margaret W, Nichols, Don J, Humphrey, Michael J, Wicks, Steve R

“…Pulsincap™ formulations designed to deliver a dose of drug following a 5-h delay were prepared to evaluate the capability of the formulation to deliver…”
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Days and Nights on the Internet: The Impact of a Diffusing Technology by Howard, P.E.N., Rainie, L., Jones, S.

“…For a growing cohort of Americans, Internet tools have become a significant conduit of social life and work life. The surveys of the Pew Internet & American…”
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Chronopharmaceutical Drug Delivery from a Pulsatile Capsule Device based on Programmable Erosion by ROSS, ALISTAIR C., MACRAE, ROSS J., WALTHER, MATHIAS, STEVENS, HOWARD N. E.

“…We report the development of a chronopharmaceutical capsule drug delivery system capable of releasing drug after pre‐determined time delays. The drug…”
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