Search Results - "Howard, M."
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1
Perinatal mental health: a review of progress and challenges
Published in World psychiatry (01-10-2020)“…Perinatal mental health has become a significant focus of interest in recent years, with investment in new specialist mental health services in some…”
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2
The ribosome binding site calculator
Published in Methods in enzymology (2011)“…The Ribosome Binding Site (RBS) Calculator is a design method for predicting and controlling translation initiation and protein expression in bacteria. The…”
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3
Translating the biology of aging into novel therapeutics for Alzheimer disease
Published in Neurology (08-01-2019)“…Aging is the leading risk factor for most chronic illnesses of old age, including Alzheimer disease (AD), a progressive neurodegenerative disease with…”
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The Importance of Cognitive Appraisal and Social Support in Pregnancy During COVID-19 from an Interdisciplinary View
Published in European psychiatry (01-06-2022)“…Aim: To describe how a US-based psychiatric Mother-Baby Unit adopted a virtual platform during the pandemic. Objectives: When the Covid-19 pandemic descended,…”
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5
A Biophysical Model of CRISPR/Cas9 Activity for Rational Design of Genome Editing and Gene Regulation
Published in PLoS computational biology (01-01-2016)“…The ability to precisely modify genomes and regulate specific genes will greatly accelerate several medical and engineering applications. The CRISPR/Cas9 (Type…”
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6
Genetic circuitry boosts cell longevity
Published in Science (American Association for the Advancement of Science) (28-04-2023)“…Reprogramming cellular dynamics is used to study and delay the onset of aging in yeast…”
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AFFECTIVE EVENTS AND THE DEVELOPMENT OF LEADER-MEMBER EXCHANGE
Published in The Academy of Management review (01-04-2017)“…We propose that consideration of affective events theory can enrich our understanding of leader-member exchange (LMX) development. Drawing from previous…”
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Main steps in DNA double-strand break repair: an introduction to homologous recombination and related processes
Published in Chromosoma (01-06-2018)“…DNA double-strand breaks arise accidentally upon exposure of DNA to radiation and chemicals or result from faulty DNA metabolic processes. DNA breaks can also…”
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Respiratory health effects of air pollution: Update on biomass smoke and traffic pollution
Published in Journal of allergy and clinical immunology (2012)“…Mounting evidence suggests that air pollution contributes to the large global burden of respiratory and allergic diseases, including asthma, chronic…”
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Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites
Published in Nucleic acids research (01-02-2014)“…The ribosome's interactions with mRNA govern its translation rate and the effects of post-transcriptional regulation. Long, structured 5' untranslated regions…”
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Automated model-predictive design of synthetic promoters to control transcriptional profiles in bacteria
Published in Nature communications (02-09-2022)“…Transcription rates are regulated by the interactions between RNA polymerase, sigma factor, and promoter DNA sequences in bacteria. However, it remains unclear…”
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A portable expression resource for engineering cross-species genetic circuits and pathways
Published in Nature communications (17-07-2015)“…Genetic circuits and metabolic pathways can be reengineered to allow organisms to process signals and manufacture useful chemicals. However, their functions…”
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13
Babesiosis in immunosuppressed hosts: pathogenesis, diagnosis and management
Published in Current opinion in infectious diseases (01-10-2024)“…This review provides the most recent evidence of the challenges that occur in the management of babesiosis in immunocompromised hosts. The epidemiology of…”
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14
Flow Cytometry: The Glass Is Half Full
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…Accompanied by a historical perspective of the field of cytometry, this introductory chapter provides a broad view of what flow cytometry can do; hence, the…”
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Translation Initiation is Controlled by RNA Folding Kinetics via a Ribosome Drafting Mechanism
Published in Journal of the American Chemical Society (08-06-2016)“…RNA folding plays an important role in controlling protein synthesis as well as other cellular processes. Existing models have focused on how RNA folding…”
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Improving treatment of HER2-positive cancers: opportunities and challenges
Published in Science translational medicine (28-03-2012)“…Amplification of the ERBB2 gene, which encodes human epidermal growth factor receptor 2 (HER2), causes the overexpression of a major proliferative driver for a…”
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Systematic review of measurement tools to assess surgeons' intraoperative cognitive workload
Published in British journal of surgery (01-04-2018)“…Background Surgeons in the operating theatre deal constantly with high‐demand tasks that require simultaneous processing of a large amount of information. In…”
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Automated design of synthetic ribosome binding sites to control protein expression
Published in Nature biotechnology (01-10-2009)“…Microbial engineering often requires fine control over protein expression-for example, to connect genetic circuits or control flux through a metabolic pathway…”
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19
Observation of Genuine One-Way Einstein-Podolsky-Rosen Steering
Published in Physical review letters (21-04-2016)“…Within the hierarchy of inseparable quantum correlations, Einstein-Podolsky-Rosen steering is distinguished from both entanglement and Bell nonlocality by its…”
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Diurnal transcriptome atlas of a primate across major neural and peripheral tissues
Published in Science (American Association for the Advancement of Science) (16-03-2018)“…Diurnal gene expression patterns underlie time-of-the-day-specific functional specialization of tissues. However, available circadian gene expression atlases…”
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