Search Results - "Howard, Karyn D"
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Pharmacokinetic comparison of six anthelmintics in sheep, goats, and cattle
Published in Journal of veterinary pharmacology and therapeutics (01-01-2021)“…This study was initiated to determine whether a comparative pharmacokinetic (PK) approach could be used to expand the pool of approved anthelmintics for minor…”
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Influence of P‐glycoprotein on the disposition of fexofenadine and its enantiomers
Published in Journal of pharmacy and pharmacology (01-03-2017)“…Objectives P‐glycoprotein (P‐gp) is responsible for the efflux of a broad variety of human and veterinary drugs. Canine P‐gp polymorphisms alter drug…”
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Identification of Multiple Constitutive and Inducible Hepatic Cytochrome P450 Enzymes in Market Weight Swine
Published in Drug metabolism and disposition (01-06-2001)“…Constitutive swine enzymes analogous to human/rat cytochrome P450 (CYP) isoforms 1A2, 2A6, 2B1/2/6, 2D6, 2E1, 3A1, and 4A1/3 were detected by Western blot…”
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Development of an Ion Chromatography–Inductively Coupled Plasma–Mass Spectrometry Method To Determine Inorganic Arsenic in Liver from Chickens Treated with Roxarsone
Published in Journal of agricultural and food chemistry (19-09-2012)“…Roxarsone, (4-hydroxy-3-nitrophenyl)arsonic acid, is an arsenic-containing compound that has been approved as a feed additive for poultry and swine since the…”
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Effects of intravenous administration of lipopolysaccharide on cytochrome P450 isoforms and hepatic drug metabolizing enzymes in swine
Published in American journal of veterinary research (01-03-2010)“…To investigate effects of bacteria-mediated inflammation on hepatic drug metabolizing enzymes (DMEs) in swine via a lipopolysaccharide (LPS) challenge…”
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Effect of oral administration of low doses of pentobarbital on the induction of cytochrome P450 isoforms and cytochrome P450-mediated reactions in immature Beagles
Published in American journal of veterinary research (01-09-2003)“…To determine the effect of oral administration of low doses of pentobarbital on cytochrome P450 (CYP) isoforms and CYP-mediated reactions in immature Beagles…”
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Gaucher's disease: lack of antibody response in 12 patients following repeated intravenous infusions of mannose terminal glucocerebrosidase
Published in Journal of immunological methods (01-03-1991)“…An amplified ELISA has been employed for monitoring the safety of repeated intravenous infusions of modified human placental glucocerebrosidase. The enzyme…”
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