Search Results - "Howard, James R."

Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme by d’Oelsnitz, Simon, Diaz, Daniel J., Kim, Wantae, Acosta, Daniel J., Dangerfield, Tyler L., Schechter, Mason W., Minus, Matthew B., Howard, James R., Do, Hannah, Loy, James M., Alper, Hal S., Zhang, Y. Jessie, Ellington, Andrew D.

“…A major challenge to achieving industry-scale biomanufacturing of therapeutic alkaloids is the slow process of biocatalyst engineering. Amaryllidaceae…”
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Data-Driven Prediction of Circular Dichroism-Based Calibration Curves for the Rapid Screening of Chiral Primary Amine Enantiomeric Excess Values by Howard, James R., Bhakare, Arya, Akhtar, Zara, Wolf, Christian, Anslyn, Eric V.

“…Here, we describe the prediction of the circular dichroism (CD) response of a three-component chiroptical sensor for enantiomeric excess (ee) determination of…”
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11B NMR Spectroscopy: Structural Analysis of the Acidity and Reactivity of Phenyl Boronic Acid–Diol Condensations by Valenzuela, Stephanie A., Howard, James R., Park, Hyun Meen, Darbha, Sriranjani, Anslyn, Eric V.

“…Phenyl boronic acids are valuable for medical diagnostics and biochemistry studies due to their ability to readily bind with carbohydrates in water…”
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Development of a Deactivation-Resistant Dialkylbiarylphosphine Ligand for Pd-Catalyzed Arylation of Secondary Amines by Feng, Kaibo, Raguram, Elaine Reichert, Howard, James R., Peters, Ellyn, Liu, Cecilia, Sigman, Matthew S., Buchwald, Stephen L.

“…Despite the prevalence of N-heteroarenes in small-molecule pharmaceuticals, Pd-catalyzed C–N cross-coupling reactions of aryl halides and amines containing…”
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Circular Dichroism Sensing: Strategies and Applications by Formen, Jeffrey S. S. K., Howard, James R., Anslyn, Eric V., Wolf, Christian

“…The analysis of the absolute configuration, enantiomeric composition, and concentration of chiral compounds are frequently encountered tasks across the…”
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11 B NMR Spectroscopy: Structural Analysis of the Acidity and Reactivity of Phenyl Boronic Acid-Diol Condensations by Valenzuela, Stephanie A, Howard, James R, Park, Hyun Meen, Darbha, Sriranjani, Anslyn, Eric V

“…Phenyl boronic acids are valuable for medical diagnostics and biochemistry studies due to their ability to readily bind with carbohydrates in water…”
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Eric's Corner - My Sabbatical Tour - "Tik-Tok of Oz"a Labs by Anslyn, Eric V., Howard, James R.

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High-throughput screening of α-chiral-primary amines to determine yield and enantiomeric excess by Moor, Sarah R., Howard, James R., Herrera, Brenden T., Anslyn, Eric V.

“…A novel screening protocol was developed using a combination of a fluorescent indicator displacement assay and a circular dichroism (CD) active Fe(II) complex…”
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A Colorimetric Method for Quantifying Cis and Trans Alkenes Using an Indicator Displacement Assay by Valenzuela, Stephanie A., Crory, Hannah S. N., Yao, Chao‐Yi, Howard, James R., Saucedo, Gabriel, Silva, A. Prasanna, Anslyn, Eric V.

“…A colorimetric indicator displacement assay (IDA) amenable to high‐throughput experimentation was developed to determine the percentage of cis and trans…”
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Circular Dichroism Sensing: Strategies and Applications by Formen, Jeffrey S. S. K., Howard, James R., Anslyn, Eric V., Wolf, Christian

“…The analysis of the absolute configuration, enantiomeric composition, and concentration of chiral compounds are frequently encountered tasks across the…”
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A Double Dissociation within Striatum between Serial Reaction Time and Radial Maze Delayed Nonmatching Performance in Rats by Mair, Robert G, Koch, Jennifer K, Newman, Julie B, Howard, James R, Burk, Joshua A

“…Lesions involving the intralaminar thalamic nuclei have been associated with impairments in working memory and intentional motor function in human clinical…”
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Air-Stable [(R3P)PdCl2]2 Complexes of Neopentylphosphines as Cross-Coupling Precatalysts: Catalytic Application and Mechanism of Catalyst Activation and Deactivation by Barnett, Kerry L, Howard, James R, Treager, Colin J, Shipley, Adam T, Stullich, Renee M, Qu, Fengrui, Gerlach, Deidra L, Shaughnessy, Kevin H

“…Air-stable [(R3P)­PdCl2]2 complexes with di-tert-butylneopentylphosphine (DTBNpP, 1a) or trineopentylphosphine (TNpP, 1b) ligands have been applied to Suzuki…”
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The reliability of skin biopsy with measurement of intraepidermal nerve fiber density by Smith, A. Gordon, Howard, James R., Kroll, Randi, Ramachandran, Pam, Hauer, Peter, Singleton, J. Robinson, McArthur, Justin

“…Intraepidermal nerve fiber density (IENFD) is a sensitive measure of small fiber injury, and holds promise as a clinical trial endpoint measure. A total of 48…”
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A Colorimetric Method for Quantifying Cis and Trans Alkenes Using an Indicator Displacement Assay by Valenzuela, Stephanie A., Crory, Hannah S. N., Yao, Chao‐Yi, Howard, James R., Saucedo, Gabriel, Silva, A. Prasanna, Anslyn, Eric V.

“…A colorimetric indicator displacement assay (IDA) amenable to high‐throughput experimentation was developed to determine the percentage of cis and trans…”
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Amines as Activating Ligands for Phosphine Palladium(II) Precatalysts: Effect of Amine Ligand Identity on the Catalyst Efficiency by Pierce, Jordan K., Hiatt, Lindsey D., Howard, James R., Hu, Huaiyuan, Qu, Fengrui, Shaughnessy, Kevin H.

“…Palladium-catalyzed cross-coupling reactions between C–X/C–H bonds and nucleophilic reagents remain a staple in organic synthesis. These reactions rely on the…”
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Degraded cardiomyocytes and dysfunctional energy metabolism; their relationship with canine cardiomyopathies by Howard, James R, McMillan, Paul N

“…Tissue sections from hearts of dogs suffering from cardiomyopathies were studied histologically and ultrastructurally. Two types of mitochondrial changes were…”
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Studying the Impact of Urban Encroachment by James R. Howard, III

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WHAT THE PUBLIC THINKS, COUNTS by HOWARD, JAMES R.

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Problems of Marketing--Discussion by Howard, James R., Brand, Charles J., Moriarty, W. D., Clark, Fred E.

“…The desire to control or dominate situations or businesses with which we may be connected is a very well established human instinct. In no stronger way has…”
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The Learner-Teacher: Nursery through Twelfth Grade by Howard, James R., III

“…Five different teaching courses are available for student teacher-learners at the Park School, which creates unique opportunities for student teachers to…”
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