Search Results - "Howard, Bruce R"

Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein by Kelly, Brian N., Kyere, Sampson, Kinde, Isaac, Tang, Chun, Howard, Bruce R., Robinson, Howard, Sundquist, Wesley I., Summers, Michael F., Hill, Christopher P.

“…The CA domain of the human immunodeficiency virus type 1 (HIV-1) Gag polyprotein plays critical roles in both the early and late phases of viral replication…”
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Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278) by Kelly, Brian N, Howard, Bruce R, Wang, Hui, Robinson, Howard, Sundquist, Wesley I, Hill, Christopher P

“…Gag, the major structural protein of retroviruses such as HIV-1, comprises a series of domains connected by flexible linkers. These domains drive viral…”
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Structural insights into the catalytic mechanism of cyclophilin A by Sundquist, Wesley I, Hill, Christopher P, Howard, Bruce R, Vajdos, Felix F, Li, Su

“…Cyclophilins constitute a ubiquitous protein family whose functions include protein folding, transport and signaling. They possess both sequence-specific…”
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Crystal Structure of Escherichia coli Malate Synthase G Complexed with Magnesium and Glyoxylate at 2.0 Å Resolution:  Mechanistic Implications by Howard, Bruce R, Endrizzi, James A, Remington, S. James

“…The crystal structure of selenomethionine-substituted malate synthase G, an 81 kDa monomeric enzyme from Escherichia coli has been determined by MAD phasing,…”
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Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G by Bracken, Colten D, Neighbor, Amber M, Lamlenn, Kenneth K, Thomas, Geoffrey C, Schubert, Heidi L, Whitby, Frank G, Howard, Bruce R

“…Malate synthase, one of the two enzymes unique to the glyoxylate cycle, is found in all three domains of life, and is crucial to the utilization of two-carbon…”
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Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag1-278 and CAN133-278 by KELLY, Brian N., HOWARD, Bruce R., WANG, Hui, ROBINSON, Howard, SUNDQUIST, Wesley I., HILL, Christopher P.

“…Gag, the major structural protein of retroviruses such as HIV-1, comprises a series of domains connected by flexible linkers. These domains drive viral…”
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Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1 - 278 and CA N 133 - 278 by Kelly, Brian N., Howard, Bruce R., Wang, Hui, Robinson, Howard, Sundquist, Wesley I., Hill, Christopher P.

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Structure of the antiviral assembly inhibitor CAP-1 bound to the HIV-1 CA protein by Kelly, Brian N., Kyere, Sampson, Kinde, Isaac, Tang, Chun, Howard, Bruce R., Robinson, Howard, Sundquist, Wesley I., Summers, Michael F., Hill, Christopher P.

“…The CA domain of the HIV-1 Gag polyprotein plays critical roles in both the early and late phases of viral replication and is therefore an attractive antiviral…”
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Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag1 - 278 and CAN 133 - 278 by Kelly, Brian N, Howard, Bruce R, Wang, Hui, Robinson, Howard, Sundquist, Wesley I, Hill, Christopher P

“…Gag, the major structural protein of retroviruses such as HIV-1, comprises a series of domains connected by flexible linkers. These domains drive viral…”
Get full text