Search Results - "Hovorka, Roman"

Coming of age: the artificial pancreas for type 1 diabetes by Thabit, Hood, Hovorka, Roman

“…The artificial pancreas (closed-loop system) addresses the unmet clinical need for improved glucose control whilst reducing the burden of diabetes self-care in…”
Get full text

Technology in the management of type 1 diabetes mellitus — current status and future prospects by Tauschmann, Martin, Hovorka, Roman

“…Type 1 diabetes mellitus (T1DM) represents 5–10% of diabetes cases worldwide. The incidence of T1DM is increasing, and there is no immediate prospect of a…”
Get full text

Closed-loop control in insulin pumps for type-1 diabetes mellitus: safety and efficacy by Fuchs, Julia, Hovorka, Roman

“…Type 1 diabetes is a lifelong disease with high management burden. The majority of people with type 1 diabetes fail to achieve glycemic targets…”
Get more information

Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range by Battelino, Tadej, Danne, Thomas, Bergenstal, Richard M, Amiel, Stephanie A, Beck, Roy, Biester, Torben, Bosi, Emanuele, Buckingham, Bruce A, Cefalu, William T, Close, Kelly L, Cobelli, Claudio, Dassau, Eyal, DeVries, J Hans, Donaghue, Kim C, Dovc, Klemen, Doyle, 3rd, Francis J, Garg, Satish, Grunberger, George, Heller, Simon, Heinemann, Lutz, Hirsch, Irl B, Hovorka, Roman, Jia, Weiping, Kordonouri, Olga, Kovatchev, Boris, Kowalski, Aaron, Laffel, Lori, Levine, Brian, Mayorov, Alexander, Mathieu, Chantal, Murphy, Helen R, Nimri, Revital, Nørgaard, Kirsten, Parkin, Christopher G, Renard, Eric, Rodbard, David, Saboo, Banshi, Schatz, Desmond, Stoner, Keaton, Urakami, Tatsuiko, Weinzimer, Stuart A, Phillip, Moshe

“…Improvements in sensor accuracy, greater convenience and ease of use, and expanding reimbursement have led to growing adoption of continuous glucose monitoring…”
Get full text

Benefits and Challenges of Current Closed-Loop Technologies in Children and Young People With Type 1 Diabetes by Fuchs, Julia, Hovorka, Roman

“…Recent advances in diabetes technology have led to the development of closed-loop insulin delivery systems for the management of type 1 diabetes. Several such…”
Get full text

Closed-Loop Insulin Delivery in Type 1 Diabetes by Thabit, Hood, MD, Hovorka, Roman, PhD

“…Advances in diabetes technology have led to significant improvements in the quality of life and care received by individuals with diabetes. Despite this,…”
Get full text

Feasibility of automated insulin delivery guided by continuous glucose monitoring in preterm infants by Beardsall, Kathryn, Thomson, Lynn, Elleri, Daniela, Dunger, David B, Hovorka, Roman

“…Closed-loop systems have been used to optimise insulin delivery in children with diabetes, but they have not been tested in neonatal intensive care. Extremely…”
Get more information

The future of continuous glucose monitoring: closed loop by Hovorka, Roman

“…Improvements in accuracy of real-time continuous glucose monitoring facilitate the development of closed-loop systems consisting of a continuous glucose…”
Get more information

Home Use of an Artificial Beta Cell in Type 1 Diabetes by Thabit, Hood, Tauschmann, Martin, Allen, Janet M, Leelarathna, Lalantha, Hartnell, Sara, Wilinska, Malgorzata E, Acerini, Carlo L, Dellweg, Sibylle, Benesch, Carsten, Heinemann, Lutz, Mader, Julia K, Holzer, Manuel, Kojzar, Harald, Exall, Jane, Yong, James, Pichierri, Jennifer, Barnard, Katharine D, Kollman, Craig, Cheng, Peiyao, Hindmarsh, Peter C, Campbell, Fiona M, Arnolds, Sabine, Pieber, Thomas R, Evans, Mark L, Dunger, David B, Hovorka, Roman

“…In two randomized trials conducted under home conditions, investigators compared closed-loop insulin delivery with sensor-augmented pump therapy in adults and…”
Get full text

Closed-loop insulin delivery for treatment of type 1 diabetes by Elleri, Daniela, Dunger, David B, Hovorka, Roman

“…Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and…”
Get full text

Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Very Young Children: A Multicenter, 3-Week, Randomized Trial by Tauschmann, Martin, Allen, Janet M, Nagl, Katrin, Fritsch, Maria, Yong, James, Metcalfe, Emily, Schaeffer, Dominique, Fichelle, Muriel, Schierloh, Ulrike, Thiele, Alena G, Abt, Daniela, Kojzar, Harald, Mader, Julia K, Slegtenhorst, Sonja, Barber, Nicole, Wilinska, Malgorzata E, Boughton, Charlotte, Musolino, Gianluca, Sibayan, Judy, Cohen, Nathan, Kollman, Craig, Hofer, Sabine E, Fröhlich-Reiterer, Elke, Kapellen, Thomas M, Acerini, Carlo L, de Beaufort, Carine, Campbell, Fiona, Rami-Merhar, Birgit, Hovorka, Roman

“…We aimed to assess the feasibility and safety of hybrid closed-loop insulin delivery in children with type 1 diabetes aged 1-7 years as well as evaluate the…”
Get full text

Glucose control in the intensive care unit by use of continuous glucose monitoring: what level of measurement error is acceptable? by Wilinska, Malgorzata E, Hovorka, Roman

“…Accuracy and frequency of glucose measurement is essential to achieve safe and efficacious glucose control in the intensive care unit. Emerging continuous…”
Get full text

The changing landscape of automated insulin delivery in the management of type 1 diabetes by Lakshman, Rama, Boughton, Charlotte, Hovorka, Roman

“…Automated insulin delivery systems, also known as closed-loop or ‘artificial pancreas’ systems, are transforming the management of type 1 diabetes. These…”
Get full text

Young Children Have Higher Variability of Insulin Requirements: Observations During Hybrid Closed-Loop Insulin Delivery by Dovc, Klemen, Boughton, Charlotte, Tauschmann, Martin, Thabit, Hood, Bally, Lia, Allen, Janet M, Acerini, Carlo L, Arnolds, Sabine, de Beaufort, Carine, Bergenstal, Richard M, Campbell, Fiona, Criego, Amy, Dunger, David B, Elleri, Daniella, Evans, Mark L, Fröhlich-Reiterer, Elke, Hofer, Sabine, Kapellen, Thomas, Leelarathna, Lalantha, Pieber, Thomas R, Rami-Merhar, Birgit, Shah, Viral N, Sibayan, Judy, Wilinska, Malgorzata E, Hovorka, Roman

“…To quantify age-related variability of insulin needs during day and night closed-loop insulin delivery. We retrospectively analyzed data from hybrid…”
Get full text

Glucose Management Indicator (GMI): Insights and Validation Using Guardian 3 and Navigator 2 Sensor Data by Leelarathna, Lalantha, Beck, Roy W, Bergenstal, Richard M, Thabit, Hood, Hovorka, Roman

Get full text

Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial by Hovorka, Roman, Dr, Allen, Janet M, RN, Elleri, Daniela, MD, Chassin, Ludovic J, PhD, Harris, Julie, RN, Xing, Dongyuan, MPH, Kollman, Craig, PhD, Hovorka, Tomas, MSc, Larsen, Anne Mette F, MSc, Nodale, Marianna, MSc, De Palma, Alessandra, MD, Wilinska, Malgorzata E, PhD, Acerini, Carlo L, MD, Dunger, David B, Prof

“…Summary Background Closed-loop systems link continuous glucose measurements to insulin delivery. We aimed to establish whether closed-loop insulin delivery…”
Get full text

Day-and-night glycaemic control with closed-loop insulin delivery versus conventional insulin pump therapy in free-living adults with well controlled type 1 diabetes: an open-label, randomised, crossover study by Bally, Lia, MD, Thabit, Hood, PhD, Kojzar, Harald, BSc, Mader, Julia K, MD, Qerimi-Hyseni, Jehona, BSc, Hartnell, Sara, BSc, Tauschmann, Martin, MD, Allen, Janet M, RN, Wilinska, Malgorzata E, PhD, Pieber, Thomas R, MD, Evans, Mark L, MD, Hovorka, Roman, Dr

“…Summary Background Tight control of blood glucose concentration in people with type 1 diabetes predisposes to hypoglycaemia. We aimed to investigate whether…”
Get full text

Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial by Thabit, Hood, PhD, Hartnell, Sara, BSc, Allen, Janet M, RN, Lake, Andrea, DipHE, Wilinska, Malgorzata E, PhD, Ruan, Yue, MEng, Evans, Mark L, MD, Coll, Anthony P, PhD, Hovorka, Roman, Dr

“…Summary Background We assessed whether fully closed-loop insulin delivery (the so-called artificial pancreas) is safe and effective compared with standard…”
Get full text

Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas by Chase, J Geoffrey, Desaive, Thomas, Bohe, Julien, Cnop, Miriam, De Block, Christophe, Gunst, Jan, Hovorka, Roman, Kalfon, Pierre, Krinsley, James, Renard, Eric, Preiser, Jean-Charles

“…There is considerable physiological and clinical evidence of harm and increased risk of death associated with dysglycemia in critical care. However, glycemic…”
Get full text

Clinical evidence for high-risk medical devices used to manage diabetes: protocol for a systematic review and meta-analysis by Bano, Arjola, Laimer, Markus, Wehrli, Faina, Kunzler, Juri, Rivero, Tania, Fraser, Alan G, Stettler, Christoph, Hovorka, Roman, Bally, Lia

“…IntroductionMedical devices, including high-risk medical devices, have greatly contributed to recent improvements in the management of diabetes. However, the…”
Get full text