Search Results - "Hovens, C M"

Prevalence of persistent platelet reactivity despite use of aspirin: A systematic review by Hovens, Marcel M.C., MD, Snoep, Jaapjan D., MSc, Eikenboom, Jeroen C.J., MD, PhD, van der Bom, Johanna G., MD, PhD, Mertens, Bart J.A., PhD, Huisman, Menno V., MD, PhD

“…Background The absolute risk of recurrences among patients using aspirin for prevention of cardiovascular events remains high. Persistent platelet reactivity…”
Get full text

International multicentre study examining selection criteria for active surveillance in men undergoing radical prostatectomy by Wong, L-M, Neal, D E, Johnston, R B, Shah, N, Sharma, N, Warren, A Y, Hovens, C M, Larry Goldenberg, S, Gleave, M E, Costello, A J, Corcoran, N M

“…Background: The controversies concerning possible overtreatment of prostate cancer, highlighted by debate over PSA screening, have highlighted active…”
Get full text

Thromboembolic resolution assessed by CT pulmonary angiography after treatment for acute pulmonary embolism by den Exter, Paul L, van Es, Josien, Kroft, Lucia J M, Erkens, Petra M G, Douma, Renée A, Mos, Inge C M, Jonkers, Gé, Hovens, Marcel M C, Durian, Marc F, ten Cate, Hugo, Beenen, Ludo F M, Kamphuisen, Pieter Willem, Huisman, Menno V

“…The systematic assessment of residual thromboembolic obstruction after treatment for acute pulmonary embolism (PE) has been understudied. This assessment is of…”
Get more information

Levels of a subpopulation of platelets, but not circulating endothelial cells, predict early treatment failure in prostate cancer patients after prostatectomy by Wong, C K E, Namdarian, B, Chua, J, Chin, X, Speirs, R, Nguyen, T, Fankhauser, M, Pedersen, J, Costello, A J, Corcoran, N M, Hovens, C M

“…Background: Angiogenesis is one of the hallmarks of cancer driving tumour growth and ultimately metastasis. Circulating endothelial cells (CECs) and…”
Get full text

Safety of using the combination of the Wells rule and D‐dimer test for excluding acute recurrent ipsilateral deep vein thrombosis by Dam, Lisette F., Gautam, Gargi, Dronkers, Charlotte E. A., Ghanima, Waleed, Gleditsch, Jostein, Heijne, Anders, Hofstee, Herman M. A., Hovens, Marcel M. C., Huisman, Menno V., Kolman, Stan, Mairuhu, Albert T. A., Nijkeuter, Mathilde, Ree, Marcel A., Rooden, Cornelis J., Westerbeek, Robin E., Westerink, Jan, Westerlund, Eli, Kroft, Lucia J. M., Klok, Frederikus A.

“…Background The diagnostic accuracy of clinical probability assessment and D‐dimer testing for clinically suspected recurrent deep vein thrombosis (DVT) is…”
Get full text

Hestia criteria can safely select patients with pulmonary embolism for outpatient treatment irrespective of right ventricular function by Zondag, W., Vingerhoets, L. M. A., Durian, M. F., Dolsma, A., Faber, L. M., Hiddinga, B. I., Hofstee, H. M. A., Hoogerbrugge, A. D. M., Hovens, M. M. C., Labots, G., Vlasveld, T., Vreede, M. J. M., Kroft, L. J. M., Huisman, M. V.

“…Summary Background There has been debate over how patients with pulmonary embolism (PE) can be safely selected for outpatient treatment. Objectives To compare…”
Get full text

Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: A systematic review and meta-analysis by Snoep, Jaapjan D., MSc, Hovens, Marcel M.C., MD, Eikenboom, Jeroen C.J., MD, PhD, van der Bom, Johanna G., MD, PhD, Jukema, J. Wouter, MD, PhD, Huisman, Menno V., MD, PhD

“…Background Despite clopidogrel therapy, patients undergoing percutaneous coronary intervention (PCI) with stenting are at risk of recurrent coronary events…”
Get full text

Heavy menstrual bleeding on direct factor Xa inhibitors: Rationale and design of the MEDEA study by Hamulyák, Eva N., Wiegers, Hanke M.G., Scheres, Luuk J.J., Hutten, Barbara A., de Lange, Maria E., Timmermans, Anne, Westerweel, Peter E., Nijziel, Marten R., Kruip, Marieke J.H.A., ten Wolde, Marije, Ypma, Paula F., Klok, Frederikus A., Nieuwenhuizen, Laurens, van Wissen, Sanne, Hovens, Marcel M.C., Faber, Laura M., Kamphuisen, Pieter W., Büller, Harry R., Middeldorp, Saskia

“…In premenopausal women, treatment with direct oral factor Xa inhibitors is associated with an increased risk of heavy menstrual bleeding (HMB) compared with…”
Get full text

Impact of Delay in Clinical Presentation on the Diagnostic Management and Prognosis of Patients with Suspected Pulmonary Embolism by DEN EXTER, Paul L, VAN ES, Josien, ERKENS, Petra M. G, VAN ROOSMALEN, Mark J. G, VAN DEN HOVEN, Pim, HOVENS, Marcel M. C, KAMPHUISEN, Pieter W, KLOK, Frederikus A, HUISMAN, Menno V

“…The nonspecific clinical presentation of pulmonary embolism (PE) frequently leads to delay in its diagnosis. This study aimed to assess the impact of delay in…”
Get full text

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo by Luwor, R B, Baradaran, B, Taylor, L E, Iaria, J, Nheu, T V, Amiry, N, Hovens, C M, Wang, B, Kaye, A H, Zhu, H-J

“…Transforming Growth Factor-β (TGF-β) and Epidermal Growth Factor (EGF) signaling pathways are both independently implicated as key regulators in tumor…”
Get full text

Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk by Stacker, Steven A, Halford, Michael M, Armes, Jane, Buchert, Michael, Meskenaite, Virginia, Grail, Dianne, Hibbs, Margaret L, Wilks, Andrew F, Farlie, Peter G, Newgreen, Don F, Hovens, Christopher M

“…Secondary palate formation is a complex process that is frequently disturbed in mammals, resulting in the birth defect cleft palate. Gene targeting has…”
Get full text

A B-cell coactivator of octamer-binding transcription factors by Gstaiger, Matthias, Knoepfel, Lea, Georgiev, Oleg, Schaffner, Walter, Hovens, Christopher M

“…The octamer motif (ATGCAAAT) paradoxically plays a central role in mediating the activity of both B-cell specific and ubiquitous promoters. It has been widely…”
Get full text

Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer by Corcoran, N M, Hovens, C M, Michael, M, Rosenthal, M A, Costello, A J

“…Background: Angiogenesis is fundamental to the progression of many solid tumours including prostate cancer. Sodium selenate is a small, water-soluble, orally…”
Get full text

Optimization of the diagnostic management of clinically suspected pulmonary embolism in hospitalized patients by Hulle, Tom, Exter, Paul L., Mos, Inge C. M., Kamphuisen, Pieter W., Hovens, Marcel M. C., Kruip, Marieke J. H. A., Es, Josien, Cate, Hugo, Huisman, Menno V., Klok, Frederikus A.

“…Summary Identical diagnostic algorithms for suspected pulmonary embolism (PE) are used for hospitalized patients and outpatients, while D‐dimer levels, risk…”
Get full text

Time-Dependent Effects of Low-Dose Aspirin on Plasma Renin Activity, Aldosterone, Cortisol, and Catecholamines by Snoep, Jaapjan D, Hovens, Marcel M.C, Pasha, Sharif M, Frölich, Marijke, Pijl, Hanno, Tamsma, Jouke T, Huisman, Menno V

“…Studies have shown that aspirin may decrease blood pressure when given at bedtime but not when administered on awakening. However, until now, a biologically…”
Get full text

Cost-effectiveness of magnetic resonance imaging for diagnosing recurrent ipsilateral deep vein thrombosis by van Dam, Lisette F., van den Hout, Wilbert B., Gautam, Gargi, Dronkers, Charlotte E.A., Ghanima, Waleed, Gleditsch, Jostein, von Heijne, Anders, Hofstee, Herman M.A., Hovens, Marcel M.C., Huisman, Menno V., Kolman, Stan, Mairuhu, Albert T.A., Nijkeuter, Mathilde, van de Ree, Marcel A., van Rooden, Cornelis J., Westerbeek, Robin E., Westerink, Jan, Westerlund, Eli, Kroft, Lucia J.M., Klok, Frederikus A.

“…The diagnostic workup of recurrent ipsilateral deep vein thrombosis (DVT) using compression ultrasonography (CUS) can be complicated by persistent…”
Get full text

Mutagenesis and selection of PDZ domains that bind new protein targets by Moelling, Karin, Schneider, Stefan, Buchert, Michael, Georgiev, Oleg, Catimel, Bruno, Halford, Michael, Stacker, Steven A, Baechi, Thomas, Hovens, Christopher M

“…PDZ domains are a recently characterized protein-recognition module. In most cases, PDZ domains bind to the C-terminal end of target proteins and are thought…”
Get full text

Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study by van der Hulle, Tom, Cheung, Whitney Y, Kooij, Stephanie, Beenen, Ludo F M, van Bemmel, Thomas, van Es, Josien, Faber, Laura M, Hazelaar, Germa M, Heringhaus, Christian, Hofstee, Herman, Hovens, Marcel M C, Kaasjager, Karin A H, van Klink, Rick C J, Kruip, Marieke J H A, Loeffen, Rinske F, Mairuhu, Albert T A, Middeldorp, Saskia, Nijkeuter, Mathilde, van der Pol, Liselotte M, Schol-Gelok, Suzanne, ten Wolde, Marije, Klok, Frederikus A, Huisman, Menno V, Fogteloo, Anne J, Kroft, Lucia J M, Brekelmans, Marjolein P, Vermaire, René M J, Bastiaansen-Bergsma, Hanny, Biedermann, Jossi S, Klijn, Adinda, van der Voort, Sanne, Lieveld, Arthur W E, de Jong, Peter Y, Schaar, Cees G, del Sol, Antonio Iglesias

“…Validated diagnostic algorithms in patients with suspected pulmonary embolism are often not used correctly or only benefit subgroups of patients, leading to…”
Get full text

High D‐dimer levels increase the likelihood of pulmonary embolism by Tick, L. W., Nijkeuter, M., Kramer, M. H. H., Hovens, M. M. C., Büller, H. R., Leebeek, F. W. G., Huisman, M. V.

“… Objective.  To determine the utility of high quantitative D‐dimer levels in the diagnosis of pulmonary embolism. Methods.  D‐dimer testing was performed in…”
Get full text

Prevention of Coagulase-Negative Staphylococcal Central Venous Catheter–Related Infection Using Urokinase Rinses: A Randomized Double-Blind Controlled Trial in Patients With Hematologic Malignancies by VAN ROODEN, Cornelis J, SCHIPPERS, Emile F, GUIOT, Henri F. L, BARGE, Renée M, HOVENS, Marcel M. C, VAN DER MEER, Felix J. M, ROSENDAAL, Frits R, HUISMAN, Menno V

“…Fibrin deposition at the intraluminal surface of the indwelling part of the central venous catheter (CVC) surface increases the risk of CVC-related…”
Get full text