Search Results - "Houtman, Judith"
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Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model
Published in Journal of neuroinflammation (02-07-2022)“…Abstract Background Deposition of amyloid beta (Aβ) and hyperphosphorylated tau along with glial cell-mediated neuroinflammation are prominent pathogenic…”
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A Nuclear Belt Fastens on Neural Cell Fate
Published in Cells (Basel, Switzerland) (27-05-2022)“…Successful embryonic and adult neurogenesis require proliferating neural stem and progenitor cells that are intrinsically and extrinsically guided into a…”
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Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells
Published in Cells (Basel, Switzerland) (26-07-2021)“…Neuronal culture was used to investigate neuronal function in physiological and pathological conditions. Despite its inevitability, primary neuronal culture…”
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Beclin1‐driven autophagy modulates the inflammatory response of microglia via NLRP3
Published in The EMBO journal (15-02-2019)“…Alzheimer's disease is characterized not only by extracellular amyloid plaques and neurofibrillary tangles, but also by microglia‐mediated neuroinflammation…”
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Lamin B1 decline underlies age‐related loss of adult hippocampal neurogenesis
Published in The EMBO journal (01-02-2021)“…Neurogenesis in the adult hippocampus declines with age, a process that has been implicated in cognitive and emotional impairments. However, the mechanisms…”
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Beclin1‐driven autophagy modulates the inflammatory response of microglia via NLRP 3
Published in The EMBO journal (15-02-2019)Get full text
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The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin
Published in Scientific reports (28-04-2020)“…Microglia, the innate immune cells of the central nervous system (CNS) survey their surroundings with their cytoplasmic processes, phagocytose debris and…”
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