Search Results - "Houssaye, Becky A."
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Early PQQ supplementation has persistent long‐term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice
Published in The FASEB journal (01-04-2017)“…Nonalcoholic fatty liver disease (NAFLD) is widespread in adults and children. Early exposure to maternal obesity or Western‐style diet (WD) increases…”
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Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in mice
Published in PloS one (25-06-2013)“…Maternal and pediatric obesity has risen dramatically over recent years, and is a known predictor of adverse long-term metabolic outcomes in offspring…”
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Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding
Published in PloS one (20-01-2014)“…Current estimates suggest that over one-third of the adult population has metabolic syndrome and three-fourths of the obese population has non-alcoholic fatty…”
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Altered gene expression and metabolism in fetal umbilical cord mesenchymal stem cells correspond with differences in 5-month-old infant adiposity gain
Published in Scientific reports (22-12-2017)“…The intrauterine period is a critical time wherein developmental exposure can influence risk for chronic disease including childhood obesity. Using umbilical…”
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Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice
Published in Hepatology communications (01-03-2018)“…Increasingly, evidence suggests that exposure to maternal obesity creates an inflammatory environment in utero, exerting long‐lasting postnatal signatures on…”
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Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues
Published in Diabetes (New York, N.Y.) (01-01-2009)“…Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues…”
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Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome
Published in The American journal of clinical nutrition (01-05-2016)“…Increased maternal body mass index (BMI) is a robust risk factor for later pediatric obesity. Accumulating evidence suggests that human milk (HM) may attenuate…”
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Women With Gestational Diabetes Mellitus Randomized to a Higher-Complex Carbohydrate/Low-Fat Diet Manifest Lower Adipose Tissue Insulin Resistance, Inflammation, Glucose, and Free Fatty Acids: A Pilot Study
Published in Diabetes care (01-01-2016)“…Diet therapy in gestational diabetes mellitus (GDM) has focused on carbohydrate restriction but is poorly substantiated. In this pilot randomized clinical…”
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PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone
Published in Journal of cell science (15-08-2005)“…Exocytotic incorporation of plasmalemmal precursor vesicles (PPVs) into the cell surface is necessary for axonal outgrowth and is known to occur mainly at the…”
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Low Neonatal Plasma n-6/n-3 PUFA Ratios Regulate Offspring Adipogenic Potential and Condition Adult Obesity Resistance
Published in Diabetes (New York, N.Y.) (01-04-2018)“…Adipose tissue expansion progresses rapidly during postnatal life, influenced by both prenatal maternal factors and postnatal developmental cues. The ratio of…”
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CCAAT/Enhancer-binding Protein β (C/EBPβ) Expression Regulates Dietary-induced Inflammation in Macrophages and Adipose Tissue in Mice
Published in The Journal of biological chemistry (05-10-2012)“…Strong evidence exists for a link between chronic low level inflammation and dietary-induced insulin resistance; however, little is known about the…”
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C/EBPβ in bone marrow is essential for diet induced inflammation, cholesterol balance, and atherosclerosis
Published in Atherosclerosis (01-07-2016)“…Abstract Background and Objective Atherosclerosis is both a chronic inflammatory disease and a lipid metabolism disorder. C/EBPβ is well documented for its…”
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Growth Cone Collapse Induced by Semaphorin 3A Requires 12/15-Lipoxygenase
Published in The Journal of neuroscience (15-06-2002)“…Detection of a repellent factor, such as a semaphorin (Sema), causes localized collapse of the growth cone and directs the neurite away from the repellent…”
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Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism
Published in JCI insight (02-11-2017)“…Maternal obesity is a global health problem that increases offspring obesity risk. The metabolic pathways underlying early developmental programming in human…”
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Thrombin-Induced Growth Cone Collapse: Involvement of Phospholipase A2 and Eicosanoid Generation
Published in The Journal of neuroscience (15-12-1999)“…The studies presented here explore intracellular signals resulting from the action of repellents on growth cones. Growth cone challenge with thrombin or…”
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Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome12
Published in The American journal of clinical nutrition (01-05-2016)“…Background: Increased maternal body mass index (BMI) is a robust risk factor for later pediatric obesity. Accumulating evidence suggests that human milk (HM)…”
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Thrombin-Induced Growth Cone Collapse: Involvement of Phospholipase A 2 and Eicosanoid Generation
Published in The Journal of neuroscience (15-12-1999)“…The studies presented here explore intracellular signals resulting from the action of repellents on growth cones. Growth cone challenge with thrombin or…”
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Growth-regulated proteins and neuronal plasticity. A commentary
Published in Molecular neurobiology (01-01-1991)“…Growth-regulated proteins (GRPs) of the neuron are synthesized during outgrowth and regeneration at an increased rate and enriched in nerve growth cones…”
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Axonal origin and purity of growth cones isolated from fetal rat brain
Published in Brain research. Developmental brain research (23-10-1996)“…The investigation of the molecular properties of nerve growth cones depends to a significant degree on their isolation from fetal brain in the form of ‘growth…”
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