Search Results - "House, Thomas"
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Epidemiological dynamics of Ebola outbreaks
Published in eLife (12-09-2014)“…Ebola is a deadly virus that causes frequent disease outbreaks in the human population. In this study, we analyse its rate of new introductions, case fatality…”
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Challenges in control of COVID-19: short doubling time and long delay to effect of interventions
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19-07-2021)“…Early assessments of the growth rate of COVID-19 were subject to significant uncertainty, as expected with limited data and difficulties in case ascertainment,…”
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3
Possible future waves of SARS-CoV-2 infection generated by variants of concern with a range of characteristics
Published in Nature communications (30-09-2021)“…Viral reproduction of SARS-CoV-2 provides opportunities for the acquisition of advantageous mutations, altering viral transmissibility, disease severity,…”
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Impact of vaccination on new SARS-CoV-2 infections in the United Kingdom
Published in Nature medicine (01-08-2021)“…The effectiveness of COVID-19 vaccination in preventing new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the general community is…”
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Vaccine Induced Herd Immunity for Control of Respiratory Syncytial Virus Disease in a Low-Income Country Setting
Published in PloS one (21-09-2015)“…Respiratory syncytial virus (RSV) is globally ubiquitous, and infection during the first six months of life is a major risk for severe disease and hospital…”
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Evidence for complex contagion models of social contagion from observational data
Published in PloS one (07-07-2017)“…Social influence can lead to behavioural 'fads' that are briefly popular and quickly die out. Various models have been proposed for these phenomena, but…”
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Insights from unifying modern approximations to infections on networks
Published in Journal of the Royal Society interface (06-01-2011)“…Networks are increasingly central to modern science owing to their ability to conceptualize multiple interacting components of a complex system. As a specific…”
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EpiBeds: Data informed modelling of the COVID-19 hospital burden in England
Published in PLoS computational biology (01-09-2022)“…The first year of the COVID-19 pandemic put considerable strain on healthcare systems worldwide. In order to predict the effect of the local epidemic on…”
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Hospital length of stay for COVID-19 patients: Data-driven methods for forward planning
Published in BMC infectious diseases (22-07-2021)“…Abstract Background Predicting hospital length of stay (LoS) for patients with COVID-19 infection is essential to ensure that adequate bed capacity can be…”
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10
Modeling infectious disease dynamics in the complex landscape of global health
Published in Science (American Association for the Advancement of Science) (13-03-2015)“…Despite some notable successes in the control of infectious diseases, transmissible pathogens still pose an enormous threat to human and animal health. The…”
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11
Social encounter networks: characterizing Great Britain
Published in Proceedings of the Royal Society. B, Biological sciences (22-08-2013)“…A major goal of infectious disease epidemiology is to understand and predict the spread of infections within human populations, with the intention of better…”
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Correction: Epidemiological dynamics of Ebola outbreaks
Published in eLife (07-11-2014)“…Epidemiological dynamics of Ebola outbreaks. eLife 3:e03908. doi: 10.7554/eLife.03908. Published 12 September 2014 In the published article text, a term was…”
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13
Eight challenges for network epidemic models
Published in Epidemics (01-03-2015)“…Highlights • Modelling transmission through networks is challenging. • We overview most of the outstanding open problems. • We identify topics ranging from…”
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14
The role of vaccination and public awareness in forecasts of Mpox incidence in the United Kingdom
Published in Nature communications (11-07-2023)“…Beginning in May 2022, Mpox virus spread rapidly in high-income countries through close human-to-human contact primarily amongst communities of gay, bisexual…”
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15
Lie Algebra Solution of Population Models Based on Time-Inhomogeneous Markov Chains
Published in Journal of applied probability (01-06-2012)“…Many natural populations are well modelled through time-inhomogeneous stochastic processes. Such processes have been analysed in the physical sciences using a…”
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Individual identity and movement networks for disease metapopulations
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-2010)“…The theory of networks has had a huge impact in both the physical and life sciences, shaping our understanding of the interaction between multiple elements in…”
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17
Social encounter networks: collective properties and disease transmission
Published in Journal of the Royal Society interface (07-11-2012)“…A fundamental challenge of modern infectious disease epidemiology is to quantify the networks of social and physical contacts through which transmission can…”
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Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time
Published in eLife (12-07-2021)“…Information on SARS-CoV-2 in representative community surveillance is limited, particularly cycle threshold (Ct) values (a proxy for viral load). We included…”
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Exact and approximate moment closures for non-Markovian network epidemics
Published in Journal of theoretical biology (07-10-2015)“…Moment-closure techniques are commonly used to generate low-dimensional deterministic models to approximate the average dynamics of stochastic systems on…”
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Scabies in residential care homes: Modelling, inference and interventions for well-connected population sub-units
Published in PLoS computational biology (01-03-2018)“…In the context of an ageing population, understanding the transmission of infectious diseases such as scabies through well-connected sub-units of the…”
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