Search Results - "Houle, Emily"

Paternal preconception phthalate exposure alters sperm methylome and embryonic programming by Oluwayiose, Oladele A., Marcho, Chelsea, Wu, Haotian, Houle, Emily, Krawetz, Stephen A., Suvorov, Alexander, Mager, Jesse, Richard Pilsner, J.

“…•Male preconception DEHP exposure in mice modified DNA methylomes in F0 sperm and F1 embryo.•Male preconception DEHP exposure altered F1 embryonic…”
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Mixtures of per- and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome by Maxwell, DruAnne L., Oluwayiose, Oladele A, Houle, Emily, Roth, Katherine, Nowak, Karolina, Sawant, Savni, Paskavitz, Amanda L., Liu, Wanqing, Gurdziel, Katherine, Petriello, Michael C., Richard Pilsner, J.

“…[Display omitted] •Exposure to PFAS chemicals in adult mice results in aberrant sperm methylation.•PFAS-exposed male offspring revealed changes in gene…”
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Urinary concentrations of phthalate and phthalate alternative metabolites and sperm DNA methylation: A multi-cohort and meta-analysis of men in preconception studies by Nowak, Karolina, Oluwayiose, Oladele A., Houle, Emily, Maxwell, DruAnne L., Sawant, Savni, Paskavitz, Amanda, Ford, Jennifer B., Minguez-Alarcon, Lidia, Calafat, Antonia M., Hauser, Russ, Pilsner, J. Richard

“…[Display omitted] •Seven phthalate metabolites were associated with cohort-specific sperm methylation.•MBzP, MiBP, and MEHP were associated with sperm…”
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Associations between Sperm Epigenetic Age and Semen Parameters: An Evaluation of Clinical and Non-Clinical Cohorts by Sawant, Savni, Oluwayiose, Oladele A, Nowak, Karolina, Maxwell, DruAnne L, Houle, Emily, Paskavitz, Amanda L, Saddiki, Hachem, Bertolla, Ricardo P, Pilsner, J Richard

“…The well-documented relationship between chronological age and the sperm methylome has allowed for the construction of epigenetic clocks that estimate the…”
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Non-coding RNAs from seminal plasma extracellular vesicles and success of live birth among couples undergoing fertility treatment by Oluwayiose, Oladele A, Houle, Emily, Whitcomb, Brian W, Suvorov, Alexander, Rahil, Tayyab, Sites, Cynthia K, Krawetz, Stephen A, Visconti, Pablo E, Pilsner, J Richard

“…Infertility remains a global health problem with male-factor infertility accounting for around 50% of cases. Understanding the molecular markers for the male…”
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Extracellular vesicle cargo of the male reproductive tract and the paternal preconception environment by Ayaz, Ahmet, Houle, Emily, Pilsner, J. Richard

“…The molecular composition of extracellular vesicles (EVs) is emerging as a novel biomarker in many areas of research including reproductive health. EVs…”
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Urinary phthalate metabolites and their mixtures are associated with advanced sperm epigenetic aging in a general population by Oluwayiose, Oladele A., Houle, Emily, Wu, Haotian, Whitcomb, Brian W., Mumford, Sunni L., Schisterman, Enrique F., Suvorov, Alexander, Balzer, Laura B., Pilsner, J. Richard

“…We have recently shown that sperm epigenetic age (SEA), a surrogate measure of biological aging in sperm, is associated with couples’ time-to-pregnancy (TTP)…”
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Urinary phthalate metabolites and small non-coding RNAs from seminal plasma extracellular vesicles among men undergoing infertility treatment by Oluwayiose, Oladele A., Houle, Emily, Whitcomb, Brian W., Suvorov, Alexander, Rahil, Tayyab, Sites, Cynthia K., Krawetz, Stephen A., Visconti, Pablo E., Pilsner, J. Richard

“…Non-coding RNA (ncRNA) cargo of extracellular vesicles (EVs) in the male reproductive tract play critical roles in semen quality and emerging evidence suggests…”
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Altered non‐coding RNA profiles of seminal plasma extracellular vesicles of men with poor semen quality undergoing in vitro fertilization treatment by Oluwayiose, Oladele A., Houle, Emily, Whitcomb, Brian W., Suvorov, Alexander, Rahil, Tayyab, Sites, Cynthia K., Krawetz, Stephen A., Visconti, Pablo, Pilsner, J. Richard

“…Background Currently, the precise mechanisms that underline male infertility are still unclear. Accumulating data implicate non‐coding RNA cargo of seminal…”
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Exploring the internal exposome of seminal plasma with semen quality and live birth: A Pilot Study by Houle, Emily, Li, YuanYuan, Schroder, Madison, McRitchie, Susan L, Rahil, Tayyab, Sites, Cynthia K, Jenkins Sumner, Susan, Pilsner, J. Richard

“…Infertility is clinically defined as the inability to achieve pregnancy within 12 months of regular unprotected sexual intercourse and affects 15% of couples…”
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Effects of preconception exposure to phthalates on mouse sperm capacitation parameters by Mohanty, Gayatri, Tourzani, Darya A, Gervasi, María G, Houle, Emily, Oluwayiose, Oladele, Suvorov, Alexander, Pilsner, J Richard, Visconti, Pablo E

“…Phthalates have been linked to adverse male reproductive health, including poor sperm quality and embryo quality as well as a longer time to pregnancy (months…”
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Association Between Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation by Oluwayiose, Oladele A, Josyula, Srinihaari, Houle, Emily, Marcho, Chelsea, Brian W Whitcomb, Rahil, Tayyab, Sites, Cynthia K, Pilsner, J Richard

“…Aim: Accumulating evidence associates sperm mitochondria DNA copy number (mtDNAcn) with male infertility and reproductive success. However, the mechanism…”
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Association between sperm mitochondarial DNA copy number and nuclear DNA methylation by Oluwayiose, Oladele A, Josyula, Srinihaari, Houle, Emily, Marcho, Chelsea, Brian W Whitcomb, Rahil, Tayyab, Sites, Cynthia K, Pilsner, J Richard

“…Accumulating evidence associates sperm mitochondria DNA copy number (mtDNAcn) with male infertility and reproductive success. However, the mechanism underlying…”
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