Search Results - "Houlbrook, Sue"

Isolation of a small molecule inhibitor of DNA base excision repair by Madhusudan, Srinivasan, Smart, Fiona, Shrimpton, Paul, Parsons, Jason L., Gardiner, Laurence, Houlbrook, Sue, Talbot, Denis C., Hammonds, Timothy, Freemont, Paul A., Sternberg, Michael J. E., Dianov, Grigory L., Hickson, Ian D.

“…The base excision repair (BER) pathway is essential for the removal of DNA bases damaged by alkylation or oxidation. A key step in BER is the processing of an…”
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Relationship of hypoxia-inducible factor (HIF)-1α and HIF-2α expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines by BLANCHER, Christine, MOORE, John W, TALKS, Kate L, HOULBROOK, Sue, HARRIS, Adrian L

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Overexpression of DNA polymerase β results in an increased rate of frameshift mutations during base excision repair by Chan, Katie, Houlbrook, Sue, Zhang, Qiu-Mei, Harrison, Mark, Hickson, Ian D., Dianov, Grigory L.

“…DNA polymerase β (Pol β) is important for the base excision repair (BER) pathway. Overexpression of Pol β is frequently found in cancer cells and is thought to…”
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Overexpression of DNA polymerase   results in an increased rate of frameshift mutations during base excision repair by Chan, K., Houlbrook, S., Zhang, Q.-M., Harrison, M., Hickson, I. D., Dianov, G. L.

“…DNA polymerase β (Pol β) is important for the base excision repair (BER) pathway. Overexpression of Pol β is frequently found in cancer cells and is thought to…”
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Evaluation of the alkaline comet assay and urinary 3-methyladenine excretion for monitoring DNA damage in melanoma patients treated with dacarbazine and tamoxifen by BRAYBROOKE, J. P, HOULBROOK, S, CRAWLEY, J. E, PROPPER, D. J, O'BYRNE, K. J, STRATFORD, I. J, HARRIS, A. L, SHUKER, D. E. G, TALBOT, D. C

“…To develop, using dacarbazine as a model, reliable techniques for measuring DNA damage and repair as pharmacodynamic endpoints for patients receiving…”
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