Search Results - "Houghton, M"
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Automated Segmentation of Intraretinal Cystoid Fluid in Optical Coherence Tomography
Published in IEEE transactions on biomedical engineering (01-04-2012)“…Cystoid macular edema (CME) is observed in a variety of ocular disorders and is strongly associated with vision loss. Optical coherence tomography (OCT)…”
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2
Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly
Published in Nature communications (20-11-2023)“…Glial-cell line derived neurotrophic factor (GDNF) bound to its co-receptor GFRα1 stimulates the RET receptor tyrosine kinase, promoting neuronal survival and…”
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3
Thermophilic methanotrophs: in hot pursuit
Published in FEMS microbiology ecology (01-09-2019)“…ABSTRACT Methane is a potent greenhouse gas responsible for 20–30% of global climate change effects. The global methane budget is ∼500–600 Tg y−1, with the…”
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Thermophilic methane oxidation is widespread in Aotearoa-New Zealand geothermal fields
Published in Frontiers in microbiology (31-08-2023)“…Geothermal areas represent substantial point sources for greenhouse gas emissions such as methane. While it is known that methanotrophic microorganisms act as…”
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Applications of Electrified Dust and Dust Devil Electrodynamics to Martian Atmospheric Electricity
Published in Space science reviews (01-11-2016)“…Atmospheric transport and suspension of dust frequently brings electrification, which may be substantial. Electric fields of 10 kV m(exp. -1) to 100 kV m(exp…”
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The Relationship between Overconfidence and the Introduction of Risky Products: Evidence from a Field Study
Published in Academy of Management journal (01-04-2003)“…To date, no field research has examined the effects of overconfidence on ill-structured decisions made by managers, such as product introductions. We explored…”
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Retinal Vasculopathy With Cerebral Leukoencephalopathy and Systemic Manifestations: Critical Role of Retina Specialists
Published in Journal of vitreoretinal diseases (Print) (01-03-2023)“…Purpose: To describe a case of retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) to enhance early recognition of this…”
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8
The reporting of uveal melanoma cases to the cancer registry in North Carolina
Published in Frontiers in oncology (03-08-2022)“…Objective To ascertain the completeness of reporting of uveal melanoma cases in North Carolina to the state’s cancer registry. Methods This was a retrospective…”
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9
K-ras activation generates an inflammatory response in lung tumors
Published in Oncogene (30-03-2006)“…Activating mutations in K-ras are one of the most common genetic alterations in human lung cancer. To dissect the role of K-ras activation in bronchial…”
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10
Superior immunogenicity of HCV envelope glycoproteins when adjuvanted with cyclic-di-AMP, a STING activator or archaeosomes
Published in Vaccine (15-12-2017)“…Three decades after the discovery, hepatitis C virus (HCV) is still the leading cause of liver transplantation and poses a major threat to global health. In…”
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Risk bias and the link between motivation and new venture post-entry international growth
Published in International business review (01-12-2013)“…► This study advances a cognitive model of new venture post-entry international growth. ► Entrepreneurs’ internationalization risk bias leads to different…”
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12
Triboelectric charging of volcanic ash from the 2011 Grímsvötn eruption
Published in Physical review letters (10-09-2013)“…The plume from the 2011 eruption of Grímsvötn was highly electrically charged, as shown by the considerable lightning activity measured by the United Kingdom…”
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13
Growth on Formic Acid Is Dependent on Intracellular pH Homeostasis for the Thermoacidophilic Methanotroph Methylacidiphilum sp. RTK17.1
Published in Frontiers in microbiology (24-03-2021)“…Members of the genus , a clade of metabolically flexible thermoacidophilic methanotrophs from the phylum Verrucomicrobia, can utilize a variety of substrates…”
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A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
Published in Structure (London) (01-07-2021)“…RET receptor tyrosine kinase plays vital developmental and neuroprotective roles in metazoans. GDNF family ligands (GFLs) when bound to cognate GFRα…”
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Ultra-widefield fundus autofluorescence in age-related macular degeneration
Published in PloS one (01-06-2017)“…Establish accuracy and reproducibility of subjective grading in ultra-widefield fundus autofluorescence (FAF) imaging in patients with age-related macular…”
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Understanding variations in reported epidemiology of major lower extremity amputation in the UK: a systematic review
Published in BMJ open (06-10-2021)“…Objective Estimate the prevalence/incidence/number of major lower extremity amputations (MLEAs) in the UK; identify sources of routinely collected electronic…”
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Estimating transient populations of unmarked individuals at a migratory stopover site using generalized N-mixture models
Published in The Journal of applied ecology (01-11-2018)“…1. Migration counts are popular indices used to monitor population trends over time. Advanced analytical methods for estimating abundance of unmarked, open…”
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The influence of social capital on strategic choice: An examination of the effects of external and internal network relationships on strategic complexity
Published in Journal of business research (01-12-2009)“…In this research we investigated the direct contributions of social capital via network involvement to the strategic complexity of firms. Specifically, we…”
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Pyrinomonas methylaliphatogenes gen. nov., sp. nov., a novel group 4 thermophilic member of the phylum Acidobacteria from geothermal soils
Published in International journal of systematic and evolutionary microbiology (2014)“…An aerobic, thermophilic, moderately acidophilic non-spore-forming bacterium, strain K22T, was isolated from geothermally heated soil at Mount Ngauruhoe, New…”
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Does the BMJ have a particular ideology to pursue in assisted dying?
Published in BMJ (31-01-2012)“…The BMJ continues its support of assisted dying by praising a self selected committee on assisted suicide chaired by an advocate of assisted suicide and…”
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