Search Results - "Hough, Cameron M."

Intense terahertz pulses inhibit Ras signaling and other cancer-associated signaling pathways in human skin tissue models by Hough, Cameron M, Purschke, David N, Huang, Chenxi, Titova, Lyubov V, Kovalchuk, Olga V, Warkentin, Brad J, Hegmann, Frank A

“…Terahertz (THz) radiation has shown unique advantages in biomedical applications for novel diagnostic technologies due to the high sensitivity to molecular…”
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Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions by Santelices, Iara B., Friesen, Douglas E., Bell, Clayton, Hough, Cameron M., Xiao, Jack, Kalra, Aarat, Kar, Piyush, Freedman, Holly, Rezania, Vahid, Lewis, John D., Shankar, Karthik, Tuszynski, Jack A.

“…Microtubules (MTs), which are cylindrical protein filaments that play crucial roles in eukaryotic cell functions, have been implicated in electrical signalling…”
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Disassembly of microtubules by intense terahertz pulses by Hough, Cameron M., Purschke, David N., Bell, Clayton, Kalra, Aarat P., Oliva, Patricia J., Huang, Chenxi, Tuszynski, Jack A., Warkentin, Brad J., Hegmann, Frank A.

“…The biological effects of terahertz (THz) radiation have been observed across multiple levels of biological organization, however the sub-cellular mechanisms…”
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Topology-Based Prediction of Pathway Dysregulation Induced by Intense Terahertz Pulses in Human Skin Tissue Models by Hough, Cameron M., Purschke, David N., Huang, Chenxi, Titova, Lyubov V., Kovalchuk, Olga, Warkentin, Brad J., Hegmann, Frank A.

“…The strong interaction between terahertz (THz) radiation and biological systems has motivated the development of several biomedical technologies, including…”
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Genomic Signature of Membrane Permeation Induced by Intense THz Pulses by Hough, Cameron M., Purschke, David N., Huang, Chenxi, Titova, Lyubov V., Kovalchuk, Olga, Warkentin, Brad J., Hegmann, Frank A.

“…Intense THz pulses have been shown to induce non-thermal biological effects at multiple scales of structural organization, including differential gene…”
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Genomic Mechanisms of THz-Induced Cancer Dysregulation in Human Skin by Hough, Cameron M., Purschke, David N., Huang, Chenxi, Titova, Lyubov V., Kovalchuk, Olga, Warkentin, Brad J., Hegmann, Frank A.

“…Intense pulses of THz radiation significantly alter gene expression and dysregulate phenotypic endpoints of cancer-related signaling pathways, including…”
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Field- and frequency-dependent disassembly of polymerized and chemically stabilized microtubules by intense THz pulses by Hough, Cameron M., Purschke, David N., Bell, Clayton, Kalra, Aarat P., Oliva, Patricia J., Huang, Chenxi, Tuszynski, Jack A., Warkentin, Brad J., Hegmann, Frank A.

“…Non-thermal biological effects of terahertz (THz) radiation have been reported in cellular- and tissue-level systems, however the fundamental interactions with…”
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Intensity-dependent Suppression of Calcium Signaling in Human Skin Tissue Models Induced by Intense THz Pulses by Hough, Cameron M., Purschke, David N., Huang, Chenxi, Titova, Lyubov V., Kovalchuk, Olga, Warkentin, Brad J., Hcgmann, Frank A.

“…The biological effects of intense THz pulses on human skin tissue models are investigated by applying gene ontology and pathway perturbation analyses to…”
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Biological effects of intense THz pulses on human skin tissue models by Hough, Cameron M., Purschke, David N., Chenxi Huang, Titova, Lyubov V., Kovalchuk, Olga, Warkentin, Brad J., Hegmann, Frank A.

“…We investigate the biological effects of intense THz pulses by measuring global differential gene expression profiles of THz-exposed human skin tissue models…”
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