Search Results - "Houge, C"

Electron backscattering diffraction investigation of focused ion beam surfaces by MATTESON, T. L, SCHWARZ, S. W, HOUGE, E. C, KEMPSHALL, B. W, GIANNUZZI, L. A

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Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity by Jarvest, Richard L, Berge, John M, Brown, Murray J, Brown, Pamela, Elder, John S, Forrest, Andrew K, Houge-Frydrych, C.S.V, O'Hanlon, Peter J, McNair, David J, Rittenhouse, Stephen, Sheppard, Robert J

“…Optimisation of the left-hand-side aryl moiety of a file compound screening hit against Staphylococcus aureus methionyl tRNA synthetase led to the…”
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Bicrystal growth and characterization of copper twist grain boundaries by Schwarz, S.M, Houge, E.C, Giannuzzi, L.A, King, A.H

“…Copper bicrystals with twist character were grown using the vertical Bridgman technique. Cu bicrystals were grown such that the grain boundary in each sample…”
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A potent seryl tRNA synthetase inhibitor SB-217452 isolated from a Streptomyces species by Stefanska, A L, Fulston, M, Houge-Frydrych, C S, Jones, J J, Warr, S R

“…A potent inhibitor of seryl tRNA synthetase, designated SB-217452 has been isolated from Streptomyces sp. ATCC 700974. The fermentation, isolation, structure…”
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Models for asymmetric [2+2] cycloadditions by Houge, C, Frisque-Hesbain, A. M, Mockel, A, Ghosez, L, Declercq, J. P, Germain, G, Van Meerssche, M

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SB-203207 and SB-203208, two novel isoleucyl tRNA synthetase inhibitors from a Streptomyces sp. II. Structure determination by Houge-Frydrych, C S, Gilpin, M L, Skett, P W, Tyler, J W

“…Two novel isoleucyl tRNA synthetase inhibitors, SB-203207 and SB-203208 have been isolated from a Streptomyces sp. and found to be structurally related to…”
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SB-219383, a novel tyrosyl tRNA synthetase inhibitor from a Micromonospora sp. II. Structure determination by Houge-Frydrych, C S, Readshaw, S A, Bell, D J

“…A novel tyrosyl tRNA synthetase inhibitor, SB-219383, has been isolated from a Micromonospora sp. The structure of SB-219383 has been elucidated by a…”
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A short, economical, and stereoselective route to prostaglandins by vicinal alkylation of cyclopentadiene by Goldstein, S, Vannes, P, Houge, C, Frisque-Hesbain, A. M, Wiaux-Zamar, C, Ghosez, L, Germain, G, Declercq, J. P, Van Meerssche, M, Arrieta, J. M

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Verifying clinical competence in critical care (continuing education credit) by Houge, M C, Deines, E S

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Chronic recording from the His bundle of the awake dog by ATLEE, J. L. III, DAYER, A. M, HOUGE, J. C

“…The conventional catheter method for measuring specialized A-V nodal and His-ventricular conduction times in the intact dog heart precludes an unanesthetized…”
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Synthesis and activity of analogues of SB-219383: novel potent inhibitors of bacterial tyrosyl tRNA synthetase by Berge, J M, Broom, N J, Houge-Frydrych, C S, Jarvest, R L, Mensah, L, McNair, D J, O'Hanlon, P J, Pope, A J, Rittenhouse, S

“…SB-219383 is a naturally occurring antibiotic, which acts by inhibition of tyrosyl tRNA synthetase. Semi-synthetic derivatives of SB-219383 were prepared with…”
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Pulsed radio frequency therapy of experimentally induced arthritis in ponies by Crawford, W.H, Houge, J.C, Neirby, D.T, Di Mino, A, Di Mino, A.A

“…The effect of pulsed radio frequency therapy (PRFT) was evaluated on seven ponies with no arthritis and in 28 ponies in which arthritis was created using…”
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Interaction of tyrosyl aryl dipeptides with S. aureus tyrosyl tRNA synthetase: Inhibition and crystal structure of a complex by Jarvest, Richard L., Berge, John M., Houge-Frydrych, Catherine S.V., Janson, Cheryl, Mensah, Lucy M., O'Hanlon, Peter J., Pope, Andrew, Saldanha, Adrian, Xiayang Qiu

“…Tyrosyl aryl dipeptide inhibitors of S. aureus tyrosyl tRNA synthetase have been identified with IC 50 values down to 0.5 μM. A crystal structure of the enzyme…”
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Portable Device for Detection of Petit Mal Epilepsy by Smith, Richard G., Houge, James C., Webster, John G.

“…We have developed and tested a portable device that analyzes the electroencephalogram (EEG) to determine if petit mal epilepsy waveforms are present…”
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Synthesis and smooth muscle relaxant activity of a new series of potassium channel activators: 3-amido-1,1-dimethylindan-2-ols by Buckle, Derek R, Arch, Jonathan R. S, Edge, Colin, Foster, Keith A, Houge-Frydrych, Catherine S. V, Pinto, Ivan L, Smith, David G, Taylor, John F, Taylor, Stephen G

“…The synthesis of a novel series of smooth muscle relaxants which have been shown to act via the opening or activation of potassium channels is described…”
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Crystal structure of Staphylococcus aureus tyrosyl‐tRNA synthetase in complex with a class of potent and specific inhibitors by Qiu, Xiayang, Janson, Cheryl A., Smith, Ward W., Green, Susan M., McDevitt, Patrick, Johanson, Kyung, Carter, Paul, Hibbs, Martin, Lewis, Ceri, Chalker, Alison, Fosberry, Andrew, Lalonde, Judith, Berge, John, Brown, Pamela, Houge‐Frydrych, Catherine S.V., Jarvest, Richard L.

“…SB‐219383 and its analogues are a class of potent and specific inhibitors of bacterial tyrosyl‐tRNA synthetases. Crystal structures of these inhibitors have…”
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Relaxant activity of 6-cyano-2,2-dimethyl-2H-1-benzopyran-4-carboxamides and -thiocarboxamides and their analogs in guinea pig trachealis by Arch, Jonathan R. S, Buckle, Derek R, Carey, Claire, Parr-Dobrzanski, Hilary, Faller, Andrew, Foster, Keith A, Houge-Frydrych, Catherine S. V, Pinto, Ivan L, Smith, David G, Taylor, Stephen G

“…Structural modifications of the potassium channel activator cromakalim (1) are described in which the amide moiety at C-4 has been replaced by carboxamide and…”
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Resistance to d  -Tubocuraine Following Denrvation by Martyn, J. A. J., Houge, C. W.

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Stylus NanoProfilometry: a new approach to CD metrology by Bindell, Jeffrey B, Houge, Erik C, Plew, Larry E, Griffith, Joseph E, Bryson, III, Charles E

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Rheumatoid arthritis: a two-axis goniometer to measure metacarpophalangeal laxity by Hasselkus, B R, Kshepakaran, K K, Houge, J C, Plautz, K A

“…A 2-axis goniometer has been developed which accommodates the metacarpophalangeal (MCP) changes of rheumatoid arthritis and permits accurate measurement of…”
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