Search Results - "Hougaard, DM"

Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study by Meier, Sandra M, Trontti, Kalevi, Purves, Kirstin L, Als, Thomas Damm, Grove, Jakob, Laine, Mikaela, Pedersen, Marianne Giørtz, Bybjerg-Grauholm, Jonas, Bækved-Hansen, Marie, Sokolowska, Ewa, Mortensen, Preben B, Hougaard, David M, Werge, Thomas, Nordentoft, Merete, Breen, Gerome, Børglum, Anders D, Eley, Thalia C, Hovatta, Iiris, Mattheisen, Manuel, Mors, Ole

“…Anxiety and stress-related disorders are among the most common mental disorders. Although family and twin studies indicate that both genetic and environmental…”
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Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis by Agerbo, Esben, Sullivan, Patrick F, Vilhjálmsson, Bjarni J, Pedersen, Carsten B, Mors, Ole, Børglum, Anders D, Hougaard, David M, Hollegaard, Mads V, Meier, Sandra, Mattheisen, Manuel, Ripke, Stephan, Wray, Naomi R, Mortensen, Preben B

“…Schizophrenia has a complex etiology influenced both by genetic and nongenetic factors but disentangling these factors is difficult. To estimate (1) how…”
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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction by Albiñana, Clara, Grove, Jakob, McGrath, John J., Agerbo, Esben, Wray, Naomi R., Bulik, Cynthia M., Nordentoft, Merete, Hougaard, David M., Werge, Thomas, Børglum, Anders D., Mortensen, Preben Bo, Privé, Florian, Vilhjálmsson, Bjarni J.

“…The accuracy of polygenic risk scores (PRSs) to predict complex diseases increases with the training sample size. PRSs are generally derived based on summary…”
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The association between neonatal vitamin D status and risk of schizophrenia by Eyles, Darryl W., Trzaskowski, Maciej, Vinkhuyzen, Anna A. E., Mattheisen, Manuel, Meier, Sandra, Gooch, Helen, Anggono, Victor, Cui, Xiaoying, Tan, Men Chee, Burne, Thomas H. J., Jang, Se Eun, Kvaskoff, David, Hougaard, David M., Nørgaard-Pedersen, Bent, Cohen, Arieh, Agerbo, Esben, Pedersen, Carsten B., Børglum, Anders D., Mors, Ole, Sah, Pankaj, Wray, Naomi R., Mortensen, Preben B., McGrath, John J.

“…Clues from the epidemiology of schizophrenia, such as the increased risk in those born in winter/spring, have led to the hypothesis that prenatal vitamin D…”
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Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study by Brikell, Isabell, Wimberley, Theresa, Albiñana, Clara, Vilhjálmsson, Bjarni Jóhann, Agerbo, Esben, Børglum, Anders D., Demontis, Ditte, Schork, Andrew J., LaBianca, Sonja, Werge, Thomas, Hougaard, David M., Nordentoft, Merete, Mors, Ole, Mortensen, Preben Bo, Petersen, Liselotte Vogdrup, Dalsgaard, Søren

“…Objective:Attention deficit hyperactivity disorder (ADHD) is a multifactorial neurodevelopmental disorder, yet the interplay between ADHD polygenic risk scores…”
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Multi-PGS enhances polygenic prediction by combining 937 polygenic scores by Albiñana, Clara, Zhu, Zhihong, Schork, Andrew J., Ingason, Andrés, Aschard, Hugues, Brikell, Isabell, Bulik, Cynthia M., Petersen, Liselotte V., Agerbo, Esben, Grove, Jakob, Nordentoft, Merete, Hougaard, David M., Werge, Thomas, Børglum, Anders D., Mortensen, Preben Bo, McGrath, John J., Neale, Benjamin M., Privé, Florian, Vilhjálmsson, Bjarni J.

“…The predictive performance of polygenic scores (PGS) is largely dependent on the number of samples available to train the PGS. Increasing the sample size for a…”
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Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots by Albiñana, Clara, Zhu, Zhihong, Borbye-Lorenzen, Nis, Boelt, Sanne Grundvad, Cohen, Arieh S., Skogstrand, Kristin, Wray, Naomi R., Revez, Joana A., Privé, Florian, Petersen, Liselotte V., Bulik, Cynthia M., Plana-Ripoll, Oleguer, Musliner, Katherine L., Agerbo, Esben, Børglum, Anders D., Hougaard, David M., Nordentoft, Merete, Werge, Thomas, Mortensen, Preben Bo, Vilhjálmsson, Bjarni J., McGrath, John J.

“…The vitamin D binding protein (DBP), encoded by the group-specific component ( GC ) gene, is a component of the vitamin D system. In a genome-wide association…”
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Genome-wide association analyses identify variants in developmental genes associated with hypospadias by Geller, Frank, Feenstra, Bjarke, Carstensen, Lisbeth, Pers, Tune H, van Rooij, Iris A L M, Körberg, Izabella Baranowska, Choudhry, Shweta, Karjalainen, Juha M, Schnack, Tine H, Hollegaard, Mads V, Feitz, Wout F J, Roeleveld, Nel, Hougaard, David M, Hirschhorn, Joel N, Franke, Lude, Baskin, Laurence S, Nordenskjöld, Agneta, van der Zanden, Loes F M, Melbye, Mads

“…Frank Geller and colleagues report the results of a large genome-wide association study of hypospadias. They identify 18 susceptibility regions for this common…”
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Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB by Eliasen, Anders U., Pedersen, Casper Emil T., Rasmussen, Morten A., Wang, Ni, Soverini, Matteo, Fritz, Amelie, Stokholm, Jakob, Chawes, Bo L., Morin, Andréanne, Bork-Jensen, Jette, Grarup, Niels, Pedersen, Oluf, Hansen, Torben, Linneberg, Allan, Mortensen, Preben B., Hougaard, David M., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Mors, Ole, Nordentoft, Merete, Børglum, Anders D., Werge, Thomas, Agerbo, Esben, Söderhall, Cilla, Altman, Matthew C., Thysen, Anna H., McKennan, Chris G., Brix, Susanne, Gern, James E., Ober, Carole, Ahluwalia, Tarunveer S., Bisgaard, Hans, Pedersen, Anders G., Bønnelykke, Klaus

“…Asthma with severe exacerbation is one of the most common causes of hospitalization among young children. Exacerbations are typically triggered by respiratory…”
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Publisher Correction: Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots by Albiñana, Clara, Zhu, Zhihong, Borbye-Lorenzen, Nis, Boelt, Sanne Grundvad, Cohen, Arieh S., Skogstrand, Kristin, Wray, Naomi R., Revez, Joana A., Privé, Florian, Petersen, Liselotte V., Bulik, Cynthia M., Plana-Ripoll, Oleguer, Musliner, Katherine L., Agerbo, Esben, Børglum, Anders D., Hougaard, David M., Nordentoft, Merete, Werge, Thomas, Mortensen, Preben Bo, Vilhjálmsson, Bjarni J., McGrath, John J.

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Genetic Variants in the 9p21.3 Locus Associated with Glioma Risk in Children, Adolescents, and Young Adults: A Case-Control Study by Dahlin, Anna M, Wibom, Carl, Andersson, Ulrika, Hougaard, David M, Bybjerg-Grauholm, Jonas, Deltour, Isabelle, Hultman, Christina M, Kähler, Anna K, Karlsson, Robert, Hjalmars, Ulf, Melin, Beatrice

“…Genome-wide association studies have identified germline genetic variants in 25 genetic loci that increase the risk of developing glioma in adulthood. It is…”
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Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis by Fadista, João, Skotte, Line, Geller, Frank, Bybjerg-Grauholm, Jonas, Gørtz, Sanne, Romitti, Paul A, Caggana, Michele, Kay, Denise M, Matsson, Hans, Boyd, Heather A, Hougaard, David M, Nordenskjöld, Agneta, Mills, James L, Melbye, Mads, Feenstra, Bjarke

“…Abstract Infantile hypertrophic pyloric stenosis (IHPS) is a disorder of young infants with a population incidence of ∼2/1000 live births, caused by…”
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Roadmap for a precision-medicine initiative in the Nordic region by Njølstad, Pål Rasmus, Andreassen, Ole Andreas, Brunak, Søren, Børglum, Anders D., Dillner, Joakim, Esko, Tõnu, Franks, Paul W., Freimer, Nelson, Groop, Leif, Heimer, Hakon, Hougaard, David M., Hovig, Eivind, Hveem, Kristian, Jalanko, Anu, Kaprio, Jaakko, Knudsen, Gun Peggy, Melbye, Mads, Metspalu, Andres, Mortensen, Preben Bo, Palmgren, Juni, Palotie, Aarno, Reed, Wenche, Stefánsson, Hreinn, Stitziel, Nathan O., Sullivan, Patrick F., Thorsteinsdóttir, Unnur, Vaudel, Marc, Vuorio, Eero, Werge, Thomas, Stoltenberg, Camilla, Stefánsson, Kári

“…The Nordic region, comprising primarily Denmark, Estonia, Finland, Iceland, Norway and Sweden, has many of the necessary characteristics for being at the…”
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Simultaneous Measurement of 25 Inflammatory Markers and Neurotrophins in Neonatal Dried Blood Spots by Immunoassay with xMAP Technology by Skogstrand, Kristin, Thorsen, Poul, Norgaard-Pedersen, Bent, Schendel, Diana E, Sorensen, Line C, Hougaard, David M

“…Inflammatory reactions and other events in early life may be part of the etiology of late-onset diseases, including cerebral palsy, autism, and type 1…”
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Genome-wide association study of Hirschsprung disease detects a novel low-frequency variant at the RET locus by Fadista, João, Lund, Marie, Skotte, Line, Geller, Frank, Nandakumar, Priyanka, Chatterjee, Sumantra, Matsson, Hans, Granström, Anna Löf, Wester, Tomas, Salo, Perttu, Virtanen, Valtter, Carstensen, Lisbeth, Bybjerg-Grauholm, Jonas, Hougaard, David Michael, Pakarinen, Mikko, Perola, Markus, Nordenskjöld, Agneta, Chakravarti, Aravinda, Melbye, Mads, Feenstra, Bjarke

“…Hirschsprung disease (HSCR) is a congenital disorder with a population incidence of ~1/5000 live births, defined by an absence of enteric ganglia along…”
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Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders by Bauer, Anna E., Liu, Xiaoqin, Byrne, Enda M., Sullivan, Patrick F., Wray, Naomi R., Agerbo, Esben, Nyegaard, Mette, Grove, Jakob, Musliner, Katherine L., Ingstrup, Katja G., Johannsen, Benedicte M. W., Mægbæk, Merete L., Wang, Yunpeng, Nordentoft, Merete, Mors, Ole, Børglum, Anders D., Werge, Thomas, Hougaard, David M., Mortensen, Preben Bo, Munk-Olsen, Trine, Meltzer-Brody, Samantha

“…Postpartum psychiatric disorders are heritable, but how genetic liability varies by other significant risk factors is unknown. We aimed to (1) estimate…”
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Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis by Strom, Nora I, Grove, Jakob, Meier, Sandra M, Bækvad-Hansen, Marie, Becker Nissen, Judith, Damm Als, Thomas, Halvorsen, Matthew, Nordentoft, Merete, Mortensen, Preben B, Hougaard, David M, Werge, Thomas, Mors, Ole, Børglum, Anders D, Crowley, James J, Bybjerg-Grauholm, Jonas, Mattheisen, Manuel

“…Among patients with obsessive-compulsive disorder (OCD), 65-85% manifest another psychiatric disorder concomitantly or at some other time point during their…”
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A Review of Major Danish Biobanks: Advantages and Possibilities of Health Research in Denmark by Laugesen, Kristina, Mengel-From, Jonas, Christensen, Kaare, Olsen, Jørn, Hougaard, David M, Boding, Lasse, Olsen, Anja, Erikstrup, Christian, Hetland, Merete Lund, Høgdall, Estrid, Kjaergaard, Alisa D, Sørensen, Erik, Brügmann, Anja, Petersen, Eva Rabing Brix, Brandslund, Ivan, Nordestgaard, Børge G, Jensen, Gorm B, Skajaa, Nils, Troelsen, Frederikke Schønfeldt, Fuglsang, Cecilia Hvitfeldt, Svingel, Lise Skovgaard, Sørensen, Henrik T

“…Biobank research may lead to an improved understanding of disease etiology and advance personalized medicine. Denmark (population ~5.9 million) provides a…”
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The genetic and phenotypic correlates of neonatal Complement Component 4 protein concentration with a focus on psychiatric and autoimmune disorders by Borbye-Lorenzen, N, Zhu, ZH, Agerbo, E, Albinana, C, Benros, ME, Bian, BL, Borglum, A, Bulik, CM, Debost, JCPG, Grove, J, Hougaard, DM, McRae, AF, Mors, O, Mortensen, PB, Musliner, K, Nordentoft, M, Petersen, LV, Prive, F, Sidorenko, J, Skogstrand, K, Werge, T, Wray, NR, Vilhjalmsson, B, McGrath, JJ

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Prediction of spontaneous preterm delivery in women with threatened preterm labour: a prospective cohort study of multiple proteins in maternal serum by Tsiartas, P, Holst, RM, Wennerholm, UB, Hagberg, H, Hougaard, DM, Skogstrand, K, Pearce, BD, Thorsen, P, Kacerovsky, M, Jacobsson, B

“…Please cite this paper as: Tsiartas P, Holst R, Wennerholm U, Hagberg H, Hougaard D, Skogstrand K, Pearce B, Thorsen P, Kacerovsky M, Jacobsson B. Prediction…”
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