Search Results - "Houdová Megová, Magdalena"
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New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity
Published in Pharmaceutics (01-08-2022)“…IL-6 signaling is involved in the pathogenesis of a number of serious diseases, including chronic inflammation and cancer. Targeting of IL-6 receptor (IL-6R)…”
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Combination of quinoxaline with pentamethinium system: Mitochondrial staining and targeting
Published in Bioorganic chemistry (01-12-2023)“…[Display omitted] •Quinoxaline conjugates with indolium PMS were prepared and full characterized.•Strong affinity and fluorescence response against…”
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The Influence of Gene Aberrations on Survival in Resected IDH Wildtype Glioblastoma Patients: A Single-Institution Study
Published in Current oncology (Toronto) (21-03-2021)“…This prospective population-based study on a group of 132 resected IDH-wildtype (IDH-wt) glioblastoma (GBM) patients assesses the prognostic and predictive…”
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IDH1/2 Mutations in Patients With Diffuse Gliomas: A Single Centre Retrospective Massively Parallel Sequencing Analysis
Published in Applied immunohistochemistry & molecular morphology (01-03-2022)“…Patients below 55 years were genetically studied because the prevalence of isocitrate dehydrogenase 1 (IDH1) decreases in older patients and on grounds of…”
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IDH1/2 Mutations in Patients With Diffuse Gliomas: A Single Centre Retrospective Massively Parallel Sequencing Analysis
Published in Applied immunohistochemistry & molecular morphology (06-12-2021)“…Patients below 55 years were genetically studied because the prevalence of isocitrate dehydrogenase 1 (IDH1) decreases in older patients and on grounds of…”
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Abstract 5396: Identification of meningioma patients in high risk of tumor recurrence using microRNA profiling
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Introduction: Meningioma represents one of the most common intracranial tumors. They are generally thought to progress from low to high-grade lesions…”
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Abstract 3695: Mapping of molecular landscape underlying drug resistance and recurrence in glioblastoma: Paired analysis of primary and recurrent tumors
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Background: Glioblastoma (GBM) is the most frequent and the most malignant brain tumor in adults. Despite aggressive therapy, overall survival of GBM…”
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IDH Mutation Analysis in Glioma Patients by CADMA Compared with SNaPshot Assay and two Immunohistochemical Methods
Published in Pathology oncology research (01-07-2019)“…Mutations in IDH1/2 genes are a marker of good prognosis for glioma patients, associated with low grade gliomas and secondary glioblastomas…”
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Abstract 2717: Identification of three distinct molecular subtypes in meningioma samples using microarrays for copy-number variants
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Background: Meningioma represents one of the most common intracranial tumors. They are generally thought to progress from low to high-grade lesions…”
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