Search Results - "Houdek, Pavel"

In vivo initiation of clock gene expression rhythmicity in fetal rat suprachiasmatic nuclei by Houdek, Pavel, Sumová, Alena

“…The mammalian suprachiasmatic nuclei (SCN) and their intrinsic rhythmicity develop gradually during ontogenesis. In the rat, the SCN forms between embryonic…”
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Early rhythmicity in the fetal suprachiasmatic nuclei in response to maternal signals detected by omics approach by Greiner, Philipp, Houdek, Pavel, Sládek, Martin, Sumová, Alena

“…The suprachiasmatic nuclei (SCN) of the hypothalamus harbor the central clock of the circadian system, which gradually matures during the perinatal period. In…”
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Development and Entrainment of the Fetal Clock in the Suprachiasmatic Nuclei: The Role of Glucocorticoids by Čečmanová, Vendula, Houdek, Pavel, Šuchmanová, Karolína, Sládek, Martin, Sumová, Alena

“…The adult circadian clock in the suprachiasmatic nucleus (SCN) of the hypothalamus is resilient to glucocorticoids (GCs). The fetal rodent SCN resembles that…”
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IDENTIFICATION OF RHYTHMICALLY EXPRESSED GENES OF THE MOUSE CHOROID PLEXUS CONTROLLED BY THE CIRCADIAN PACEMAKER IN THE SUPRACHIASMATIC NUCLEUS BY TIME-RESOLVED RNASEQ by Sládek, Martin, Houdek, Pavel, Sumová, Alena

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DECODING THE IMPACT OF THE REVERSED RESTRICTED FEEDING ON THE CIRCADIAN CLOCK IN CHOROID PLEXUS by Dočkal, Tereza, Houdek, Pavel, Sumová, Alena

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Lithium affects the circadian clock in the choroid plexus – A new role for an old mechanism by Liška, Karolína, Dočkal, Tereza, Houdek, Pavel, Sládek, Martin, Lužná, Vendula, Semenovykh, Kateryna, Drapšin, Milica, Sumová, Alena

“…Lithium is an effective mood stabilizer, but the mechanism of its therapeutic action is not well understood. We investigated the effect of lithium on the…”
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The circadian clock in the choroid plexus drives rhythms in multiple cellular processes under the control of the suprachiasmatic nucleus by Sládek, Martin, Houdek, Pavel, Myung, Jihwan, Semenovykh, Kateryna, Dočkal, Tereza, Sumová, Alena

“…Choroid plexus (ChP), the brain structure primarily responsible for cerebrospinal fluid production, contains a robust circadian clock, whose role remains to be…”
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Challenging the Integrity of Rhythmic Maternal Signals Revealed Gene-Specific Responses in the Fetal Suprachiasmatic Nuclei by Lužná, Vendula, Houdek, Pavel, Liška, Karolína, Sumová, Alena

“…During fetal stage, maternal circadian system sets the phase of the developing clock in the suprachiasmatic nuclei (SCN) via complex pathways. We addressed the…”
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Targeted modification of the Per2 clock gene alters circadian function in mPer2luciferase (mPer2Luc) mice by Ralph, Martin R, Shi, Shu-Qun, Johnson, Carl H, Houdek, Pavel, Shrestha, Tenjin C, Crosby, Priya, O'Neill, John S, Sládek, Martin, Stinchcombe, Adam R, Sumová, Alena

“…Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and…”
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Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a by Shi, Shu-Qun, Mahoney, Carrie E, Houdek, Pavel, Zhao, Wenling, Anderson, Matthew P, Zhuo, Xinming, Beaudet, Arthur, Sumova, Alena, Scammell, Thomas E, Johnson, Carl Hirschie

“…Normal neurodevelopment requires precise expression of the key ubiquitin ligase gene . Comparing newly generated mouse models for downregulation (models of…”
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The McGill Transgenic Rat Model of Alzheimer's Disease Displays Cognitive and Motor Impairments, Changes in Anxiety and Social Behavior, and Altered Circadian Activity by Petrasek, Tomas, Vojtechova, Iveta, Lobellova, Veronika, Popelikova, Anna, Janikova, Martina, Brozka, Hana, Houdek, Pavel, Sladek, Martin, Sumova, Alena, Kristofikova, Zdenka, Vales, Karel, Stuchlík, Ales

“…The McGill-R-Thy1-APP transgenic rat is an animal model of the familial form of Alzheimer's disease (AD). This model mirrors several neuropathological…”
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Early rhythmicity in the fetal suprachiasmatic nuclei in response to maternal signals detected by omics approach by Philipp Greiner, Pavel Houdek, Martin Sládek, Alena Sumová

“…The suprachiasmatic nuclei (SCN) of the hypothalamus harbor the central clock of the circadian system, which gradually matures during the perinatal period. In…”
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Circadian profiling reveals distinct regulation of endocannabinoid system in the rat plasma, liver and adrenal glands by light-dark and feeding cycles by Sládek, Martin, Houdek, Pavel, Sumová, Alena

“…Circadian clocks coordinate physiological and behavioral rhythms that allow the organism to anticipate and adapt to daily changes in environment. The…”
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Circadian clock in choroid plexus is resistant to immune challenge but dampens in response to chronodisruption by Drapšin, Milica, Dočkal, Tereza, Houdek, Pavel, Sládek, Martin, Semenovykh, Kateryna, Sumová, Alena

“…•Choroid plexus in brain ventricles plays significant role in brain homeostasis.•Choroid plexus harbors robust circadian clock that controls its…”
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Modulation of single cell circadian response to NMDA by diacylglycerol lipase inhibition reveals a role of endocannabinoids in light entrainment of the suprachiasmatic nucleus by Sládek, Martin, Liška, Karolína, Houdek, Pavel, Sumová, Alena

“…Suprachiasmatic nucleus (SCN) of the hypothalamus is the master clock that drives circadian rhythms in physiology and behavior and adjusts their timing to…”
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Misaligned feeding schedule elicits divergent circadian reorganizations in endo- and exocrine pancreas clocks by Honzlová, Petra, Novosadová, Zuzana, Houdek, Pavel, Sládek, Martin, Sumová, Alena

“…Misaligned feeding may lead to pancreatic insufficiency, however, whether and how it affects circadian clock in the exocrine pancreas is not known. We exposed…”
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Chronic disruptions of circadian sleep regulation induce specific proinflammatory responses in the rat colon by Polidarová, Lenka, Houdek, Pavel, Sumová, Alena

“…Exposure to environmental conditions that disturb the daily rhythms has been shown to enhance the proinflammatory responses of immunostimulant-challenged…”
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Nicotinic Acetylcholine Receptors Expressed by Striatal Interneurons Inhibit Striatal Activity and Control Striatal-Dependent Behaviors by Abbondanza, Alice, Ribeiro Bas, Irina, Modrak, Martin, Capek, Martin, Minich, Jessica, Tyshkevich, Alexandra, Naser, Shahed, Rangotis, Revan, Houdek, Pavel, Sumova, Alena, Dumas, Sylvie, Bernard, Veronique, Janickova, Helena

“…Acetylcholine is an important modulator of striatal activity, and it is vital to controlling striatal-dependent behaviors, including motor and cognitive…”
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Targeted modification of the Per2 clock gene alters circadian function in mPer2.sup.luciferase by Ralph, Martin R, Shi, Shu-qun, Johnson, Carl H, Houdek, Pavel, Shrestha, Tenjin C, Crosby, Priya, O'Neill, John S, Sládek, Martin, Stinchcombe, Adam R, Sumová, Alena

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High Sensitivity of the Circadian Clock in the Hippocampal Dentate Gyrus to Glucocorticoid- and GSK3-Beta-Dependent Signals by Liška, Karolína, Sládek, Martin, Houdek, Pavel, Shrestha, Norzin, Lužná, Vendula, Ralph, Martin R, Sumová, Alena

“…Circadian clocks in the hippocampus (HPC) align memory processing with appropriate time of day. Our study was aimed at ascertaining the specificity of glycogen…”
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