Search Results - "Houck, D R"

Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation by Wanner, Roger M., Spielmann, Patrick, Stroka, Deborah M., Camenisch, Gieri, Camenisch, Isabelle, Scheid, Annette, Houck, David R., Bauer, Christian, Gassmann, Max, Wenger, Roland H.

“…Induction of erythropoietin (Epo) expression under hypoxic conditions is mediated by the heterodimeric hypoxia-inducible factor (HIF)-1. Following binding to…”
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Intestinal absorption and tissue distribution of [14C]pyrroloquinoline quinone in mice by Smidt, C R, Unkefer, C J, Houck, D R, Rucker, R B

“…Pyrroloquinoline quinone (PQQ) functions as a cofactor for prokaryotic oxidoreductases, such as methanol dehydrogenase and membrane-bound glucose…”
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WIN 64821, a novel neurokinin antagonist produced by an Aspergillus sp. III. Biosynthetic analogs by Popp, J L, Musza, L L, Barrow, C J, Rudewicz, P J, Houck, D R

“…WIN 64821 (1) is a substance P (SP) antagonist isolated from a fungal culture (Aspergillus sp., SC319). It is a symmetrical dimer biosynthesized from four…”
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WIN 64821, a novel neurokinin antagonist produced by an Aspergillus sp. I. Fermentation and isolation by Sedlock, D M, Barrow, C J, Brownell, J E, Hong, A, Gillum, A M, Houck, D R

“…WIN 64821, a nonpeptide neurokinin antagonist, was isolated from a strain of Aspergillus sp., SC319. The compound was produced in different fermentation media…”
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On the biosynthesis of asperlicin and the directed biosynthesis of analogs in Aspergillus alliaceus by Houck, D R, Ondeyka, J, Zink, D L, Inamine, E, Goetz, M A, Hensens, O D

“…Feeding of 14C-labeled amino acids to resting cells of Aspergillus alliaceus strongly supported the intuitive hypothesis that asperlicin is biosynthesized from…”
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Stereochemistry of sodium borohydride reduction of tryptophan synthase of Escherichia coli and its amino acid Schiff's bases by Miles, E W, Houck, D R, Floss, H G

“…Tryptophan synthase alpha 2 beta 2 complex containing [4'-3H]pyridoxal phosphate was reduced with sodium borohydride in the presence of various substrates and…”
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Isolation and structure elucidation of two new calpain inhibitors from Streptomyces griseus by Alvarez, M E, Houck, D R, White, C B, Brownell, J E, Bobko, M A, Rodger, C A, Stawicki, M B, Sun, H H, Gillum, A M, Cooper, R

“…Two new peptides, a diketopiperazine of N-methyltyrosine (1) and a tetrapeptide containing N-methyltyrosine (2), were isolated from an actinomycete strain…”
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1H and 13C NMR assignments of the thiopeptide antibiotic nosiheptide by Mocek, U, Chen, L C, Keller, P J, Houck, D R, Beale, J M, Floss, H G

“…The 1H and 13C NMR spectra of nosiheptide have been assigned by use of 2D NMR techniques on unlabeled samples and biosynthetically multiple-labeled samples…”
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Oxalic acid biosynthesis and oxalacetate acetylhydrolase activity in Streptomyces cattleya by Houck, D R, Inamine, E

“…In addition to producing the antibiotic thienamycin, Streptomyces cattleya accumulates large amounts of oxalic acid during the course of a fermentation. Washed…”
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Method to predict the minimum measurement and experiment durations needed to achieve converged and significant results in a wind energy field experiment by Houck, Daniel R, de Velder, Nathaniel B, Maniaci, David C, Houchens, Brent C

“…Experiments offer incredible value to science, but results must always come with an uncertainty quantification to be meaningful. This requires grappling with…”
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Mycoepoxydiene represents a novel class of fungal metabolites by Cai, Ping, McPhail, Andrew T., Krainer, Eduardo, Katz, Barry, Pearce, Cedric, Boros, Christie, Caceres, Bernardo, Smith, David, Houck, D.R.

“…A novel epoxycyclooctadiene-δ-lactone, mycoepoxydiene, was isolated from a fungal culture (OS-F66617). Its structure and relative stererochemistry were…”
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NYX-2925 Is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory by Khan, M Amin, Houck, David R, Gross, Amanda L, Zhang, Xiao-Lei, Cearley, Cassia, Madsen, Torsten M, Kroes, Roger A, Stanton, Patric K, Burgdorf, Jeffrey, Moskal, Joseph R

“…N-methyl-D-aspartate receptors are one member of a family of ionotropic glutamate receptors that play a pivotal role in synaptic plasticity processes…”
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A Metalloproteinase Inhibitor from Doliocarpus verruculosus by Sun, Hao H., Kaplita, Paul V., Houck, David R., Stawicki, Mary B., McGarry, Ruthann, Wahl, Robert C., Gillum, Amanda M., Cooper, Raymond

“…In our natural products screening programme for the discovery of competitive inhibitors of the matrix metalloproteinases, stromelysin and collagenase, we have…”
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Comparison of native matrix metalloproteinases and their recombinant catalytic domains using a novel radiometric assay by Brownell, J, Earley, W, Kunec, E, Morgan, B A, Olyslager, B, Wahl, R C, Houck, D R

“…A novel radiometric assay was developed for human fibroblast collagenase (matrix metalloproteinase-1, MMP-1), stromelysin (MMP-3), and their recombinant…”
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Biosynthesis of the modified peptide antibiotic nosiheptide in Streptomyces actuosus by Houck, David R, Chen, Li Chun, Keller, Paul J, Beale, John M, Floss, Heinz G

“…The biosynthesis of the modified, sulfur-rich peptide antibiotic nosiheptide (1) was studied in feeding experiments with radioactive and super(13)C-labeled…”
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Stereochemistry of methylation in thienamycin biosynthesis: example of a methyl transfer from methionine with retention of configuration by Houck, David R, Kobayashi, Koji, Williamson, Joanne M, Floss, Heinz G

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Biosynthesis of the modified peptide antibiotic nosiheptide in Streptomyces actuosus by Houck, David R, Chen, Li Chun, Keller, Paul J, Beale, John M, Floss, Heinz G

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Stereochemical course of the transmethylation catalyzed by histamine N-methyltransferase by Asano, Y, Woodard, R W, Houck, D R, Floss, H G

“…The stereochemical course of the methyl group transfer catalyzed by histamine N-methyltransferase was studied using S-adenosylmethionine (AdoMet), which…”
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Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation by Wanner, Roger M., Spielmann, Patrick, Stroka, Deborah M., Camenisch, Gieri, Camenisch, Isabelle, Scheid, Annette, Houck, David R., Bauer, Christian, Gassmann, Max, Wenger, Roland H.

“…Induction of erythropoietin (Epo) expression under hypoxic conditions is mediated by the heterodimeric hypoxia-inducible factor (HIF)-1. Following binding to…”
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Biogenesis of pyrroloquinoline quinone from 3C-labeled tyrosine by Unkefer, C J, Houck, D R, Britt, B M, Sosnick, T R, Hanners, J L

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