Search Results - "Houben, Roland"

Reduced frequency of migraine attacks following coronavirus disease 2019: a case report by Houben, Roland

“…Severe acute respiratory syndrome coronavirus 2 is a virus affecting different organs and causing a wide variety and severity of symptoms. Headache as well as…”
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IFN-gamma-induced PD-L1 expression in melanoma depends on p53 expression by Thiem, Alexander, Hesbacher, Sonja, Kneitz, Hermann, di Primio, Teresa, Heppt, Markus V, Hermanns, Heike M, Goebeler, Matthias, Meierjohann, Svenja, Houben, Roland, Schrama, David

“…Immune checkpoint inhibition and in particular anti-PD-1 immunotherapy have revolutionized the treatment of advanced melanoma. In this regard, higher tumoral…”
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Merkel Cell Polyomavirus-Infected Merkel Cell Carcinoma Cells Require Expression of Viral T Antigens by Houben, Roland, Shuda, Masahiro, Weinkam, Rita, Schrama, David, Feng, Huichen, Chang, Yuan, Moore, Patrick S, Becker, Jürgen C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diagnostic accuracy of a panel of immunohistochemical and molecular markers to distinguish Merkel cell carcinoma from other neuroendocrine carcinomas by Kervarrec, Thibault, Tallet, Anne, Miquelestorena-Standley, Elodie, Houben, Roland, Schrama, David, Gambichler, Thilo, Berthon, Patricia, Le Corre, Yannick, Hainaut-Wierzbicka, Ewa, Aubin, Francois, Bens, Guido, Tabareau-Delalande, Flore, Beneton, Nathalie, Fromont, Gaëlle, Arbion, Flavie, Leteurtre, Emmanuelle, Touzé, Antoine, Samimi, Mahtab, Guyétant, Serge

“…Merkel cell carcinoma is a rare neuroendocrine carcinoma of the skin mostly induced by Merkel cell polyomavirus integration. Cytokeratin 20 (CK20) positivity…”
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Morphologic and immunophenotypical features distinguishing Merkel cell polyomavirus-positive and negative Merkel cell carcinoma by Kervarrec, Thibault, Tallet, Anne, Miquelestorena-Standley, Elodie, Houben, Roland, Schrama, David, Gambichler, Thilo, Berthon, Patricia, Le Corre, Yannick, Hainaut-Wierzbicka, Ewa, Aubin, Francois, Bens, Guido, Tabareau-Delalande, Flore, Beneton, Nathalie, Fromont, Gaëlle, Arbion, Flavie, Leteurtre, Emmanuelle, Herfs, Michael, Touzé, Antoine, Samimi, Mahtab, Guyétant, Serge

“…In 2008, Feng et al. identified Merkel cell polyomavirus integration as the primary oncogenic event in ~80% of Merkel cell carcinoma cases. The remaining…”
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Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression by Dogliotti, Giada, Kullmann, Lars, Dhumale, Pratibha, Thiele, Christian, Panichkina, Olga, Mendl, Gudrun, Houben, Roland, Haferkamp, Sebastian, Püschel, Andreas W., Krahn, Michael P.

“…The serine/threonine kinase LKB1 regulates various cellular processes such as cell proliferation, energy homeostasis and cell polarity and is frequently…”
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Loss of p14 diminishes immunogenicity in melanoma via non‐canonical Wnt signaling by reducing the peptide surface density by Wohlfarth, Jonas, Kosnopfel, Corinna, Faber, Dominic, Berthold, Marion, Siedel, Claudia, Bernhardt, Melissa, Schlosser, Andreas, Aprati, Tyler, Liu, David, Schrama, David, Houben, Roland, Schadendorf, Dirk, Goebeler, Matthias, Meierjohann, Svenja, Schilling, Bastian

“…Immunotherapy has achieved tremendous success in melanoma. However, only around 50% of advanced melanoma patients benefit from immunotherapy. Cyclin‐dependent…”
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Author Correction: Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression by Dogliotti, Giada, Kullmann, Lars, Dhumale, Pratibha, Thiele, Christian, Panichkina, Olga, Mendl, Gudrun, Houben, Roland, Haferkamp, Sebastian, Püschel, Andreas W., Krahn, Michael P.

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Merkel Cell Polyomavirus Large T Antigen is Dispensable in G2 and M-Phase to Promote Proliferation of Merkel Cell Carcinoma Cells by Houben, Roland, Ebert, Marlies, Hesbacher, Sonja, Kervarrec, Thibault, Schrama, David

“…Merkel cell carcinoma (MCC) is an aggressive skin cancer frequently caused by the Merkel cell polyomavirus (MCPyV), and proliferation of MCPyV-positive MCC…”
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Activation of the PI3K/AKT pathway in Merkel cell carcinoma by Hafner, Christian, Houben, Roland, Baeurle, Anne, Ritter, Cathrin, Schrama, David, Landthaler, Michael, Becker, Juergen C

“…Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with an increasing incidence. The understanding of the molecular carcinogenesis of MCC is…”
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Elucidating the mechanism of action of domatinostat (4SC-202) in cutaneous T cell lymphoma cells by Wobser, Marion, Weber, Alexandra, Glunz, Amelie, Tauch, Saskia, Seitz, Kristina, Butelmann, Tobias, Hesbacher, Sonja, Goebeler, Matthias, Bartz, René, Kohlhof, Hella, Schrama, David, Houben, Roland

“…Targeting epigenetic modifiers is effective in cutaneous T cell lymphoma (CTCL). However, there is a need for further improvement of this therapeutic approach…”
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Antibody-Drug Conjugates as an Emerging Therapy in Oncodermatology by Esnault, Clara, Schrama, David, Houben, Roland, Guyétant, Serge, Desgranges, Audrey, Martin, Camille, Berthon, Patricia, Viaud-Massuard, Marie-Claude, Touzé, Antoine, Kervarrec, Thibault, Samimi, Mahtab

“…Antibody-drug conjugates (ADCs) are an emerging class of therapeutics, with twelve FDA- and EMA-approved drugs for hematological and solid cancers. Such drugs…”
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The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma by Adam, Christian, Baeurle, Anne, Brodsky, Jeffrey L, Wipf, Peter, Schrama, David, Becker, Jürgen Christian, Houben, Roland

“…Merkel Cell Carcinoma (MCC) is a rare and highly aggressive neuroendocrine skin cancer for which no effective treatment is available. MCC represents a human…”
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Investigation of the RB1-SOX2 axis constitutes a tool for viral status determination and diagnosis in Merkel cell carcinoma by Thanguturi, Soumanth, Tallet, Anne, Miquelestorena-Standley, Elodie, Coco, Catherine, Le Corre, Yannick, Hainaut-Wierzbicka, Ewa, Blom, Astrid, Saiag, Philippe, Beneton, Nathalie, Bens, Guido, Zaragoza, Julia, Nardin, Charlee, Aubin, François, Dinulescu, Monica, Machet, Marie-Christine, Houben, Roland, Schrama, David, Collin, Christine, Fromont, Gaëlle, Jullie, Marie-Laure, Macagno, Nicolas, Gaboriaud, Pauline, Berthon, Patricia, Touzé, Antoine, Guyétant, Serge, Samimi, Mahtab, Kervarrec, Thibault

“…MCC (Merkel cell carcinoma) is an aggressive neuroendocrine cutaneous neoplasm. Integration of the Merkel cell polyomavirus (MCPyV) is observed in about 80% of…”
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Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome by Haymerle, Georg, Janik, Stefan, Fochtmann, Alexandra, Pammer, Johannes, Schachner, Helga, Nemec, Lucas, Mildner, Michael, Houben, Roland, Grasl, Matthaeus Ch, Erovic, Boban M

“…The aim of this study was to determine the prevalence of MCPyV in Merkel cell carcinoma (MCC) primaries versus lymph node metastasis and to evaluate possible…”
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Overexpression of the KIT/SCF in Uveal Melanoma Does Not Translate into Clinical Efficacy of Imatinib Mesylate by Hofmann, Uta B., Kauczok-Vetter, Claudia S., Houben, Roland, Becker, Jürgen C.

“…Purpose: Recently, gene amplification and overexpression of KIT as well as activating mutations in the KIT gene have been described to occur in certain subsets…”
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MC Polyomavirus Is Frequently Present in Merkel Cell Carcinoma of European Patients by Becker, Jürgen C., Houben, Roland, Ugurel, Selma, Trefzer, Uwe, Pföhler, Claudia, Schrama, David

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Detection of the Merkel cell polyomavirus in the neuroendocrine component of combined Merkel cell carcinoma by Kervarrec, Thibault, Samimi, Mahtab, Gaboriaud, Pauline, Gheit, Tarik, Beby-Defaux, Agnès, Houben, Roland, Schrama, David, Fromont, Gaëlle, Tommasino, Massimo, Le Corre, Yannick, Hainaut-Wierzbicka, Eva, Aubin, Francois, Bens, Guido, Maillard, Hervé, Furudoï, Adeline, Michenet, Patrick, Touzé, Antoine, Guyétant, Serge

“…Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin. The main etiological agent is Merkel cell polyomavirus (MCPyV), detected in…”
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Molecular pathogenesis of Merkel cell carcinoma by Houben, Roland, Schrama, David, Becker, Jürgen C.

“…:  Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer which is twice as lethal as melanoma as more than one‐third of MCC patients…”
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The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report by Becker, Jürgen C, Houben, Roland, Vetter, Claudia S, Bröcker, Eva B

“…Since tacrolimus ointment was approved by the U.S. Food and Drug Administration (FDA) as a promising treatment for atopic dermatitis, it has been approved in…”
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