Search Results - "Houben, Judith H. P. M"

Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors by Beenakker, Thomas J. M, Wander, Dennis P. A, Offen, Wendy A, Artola, Marta, Raich, Lluís, Ferraz, Maria J, Li, Kah-Yee, Houben, Judith H. P. M, van Rijssel, Erwin R, Hansen, Thomas, van der Marel, Gijsbert A, Codée, Jeroen D. C, Aerts, Johannes M. F. G, Rovira, Carme, Davies, Gideon J, Overkleeft, Herman S

“…The conformational analysis of glycosidases affords a route to their specific inhibition through transition-state mimicry. Inspired by the rapid reaction rates…”
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AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis by Meley, Daniel, Bauvy, Chantal, Houben-Weerts, Judith H.P.M., Dubbelhuis, Peter F., Helmond, Mariette T.J., Codogno, Patrice, Meijer, Alfred J.

“…Interruption of mTOR-dependent signaling by rapamycin is known to stimulate autophagy, both in mammalian cells and in yeast. Because activation of AMPK also…”
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Microglial Activation After Systemic Stimulation With Lipopolysaccharide and Escherichia coli by Hoogland, Inge C M, Westhoff, Dunja, Engelen-Lee, Joo-Yeon, Melief, Jeroen, Valls Serón, Mercedes, Houben-Weerts, Judith H M P, Huitinga, Inge, van Westerloo, David J, van der Poll, Tom, van Gool, Willem A, van de Beek, Diederik

“…Microglial activation after systemic infection has been suggested to mediate sepsis-associated delirium. A systematic review of animal studies suggested…”
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Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli by Hoogland, Inge C M, Yik, Jutka, Westhoff, Dunja, Engelen-Lee, Joo-Yeon, Valls Seron, Merche, Man, Wing Kit, Houben-Weerts, Judith H P M, Tanck, Michael W T, van Westerloo, David J, van der Poll, Tom, van Gool, Willem A, van de Beek, Diederik

“…Development of neurodegeneration in older people has been associated with microglial cell activation triggered by systemic infection. We hypothesize that α7…”
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Regulation of adiponectin secretion by insulin and amino acids in 3T3-L1 adipocytes by Blümer, Regje M.E, van Roomen, Cindy P, Meijer, Alfred J, Houben-Weerts, Judith H.P.M, Sauerwein, Hans P, Dubbelhuis, Peter F

“…Abstract Adiponectin is a fat cell–derived hormone with insulin-sensitizing properties. Low plasma adiponectin levels are associated with insulin resistance as…”
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Microglial response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice after systemic stimulation with Escherichia coli by Hoogland, Inge C.M., Yik, Jutka, Westhoff, Dunja, Engelen-Lee, Joo-Yeon, Valls Seron, Merche, Man, Wing-Kit, Houben-Weerts, Judith H.P.M., Tanck, Michael W., van Westerloo, David J., van der Poll, Tom, van Gool, Willem A., van de Beek, Diederik

“…•Loss of function of TREM2 during systemic infection leads to an increased number of microglial cells in thalamus after inoculation.•Loss of function of TREM2…”
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Aging and Microglial Response following Systemic Stimulation with Escherichia coli in Mice by Hoogland, Inge C M, Westhoff, Dunja, Engelen-Lee, Joo-Yeon, Valls Seron, Mercedes, Houben-Weerts, Judith H M P, van Westerloo, David J, van der Poll, Tom, van Gool, Willem A, van de Beek, Diederik

“…Systemic infection is an important risk factor for the development cognitive impairment and neurodegeneration in older people. Animal experiments show that…”
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In Vivo Mitochondrial Oxygen Tension Measured by a Delayed Fluorescence Lifetime Technique by Mik, Egbert G., Johannes, Tanja, Zuurbier, Coert J., Heinen, Andre, Houben-Weerts, Judith H.P.M., Balestra, Gianmarco M., Stap, Jan, Beek, Johan F., Ince, Can

“…Mitochondrial oxygen tension (mitoPO2) is a key parameter for cellular function, which is considered to be affected under various pathophysiological…”
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Microglial cell response in [alpha]7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli by Hoogland, Inge C. M, Yik, Jutka, Westhoff, Dunja, Engelen-Lee, Joo-Yeon, Valls Seron, Merche, Man, Wing Kit, Houben-Weerts, Judith H. P. M, Tanck, Michael W. T, van Westerloo, David J, van der Poll, Tom, van Gool, Willem A, van de Beek, Diederik

“…Background Development of neurodegeneration in older people has been associated with microglial cell activation triggered by systemic infection. We hypothesize…”
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