Search Results - "Hou Huagang"

Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo by Montano, Ryan, Thompson, Ruth, Chung, Injae, Hou, Huagang, Khan, Nadeem, Eastman, Alan

“…Chk1 inhibitors have emerged as promising anticancer therapeutic agents particularly when combined with antimetabolites such as gemcitabine, cytarabine or…”
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A Bi-Temporal-Feature-Difference- and Object-Based Method for Mapping Rice-Crayfish Fields in Sihong, China by Ma, Siqi, Wang, Danyang, Yang, Haichao, Hou, Huagang, Li, Cheng, Li, Zhaofu

“…Rice-crayfish field (i.e., RCF) distribution mapping is crucial for the adjustment of the local crop cultivation structure and agricultural development. The…”
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The role of oxygen during fracture healing by Lu, Chuanyong, Saless, Neema, Wang, Xiaodong, Sinha, Arjun, Decker, Sebastian, Kazakia, Galateia, Hou, Huagang, Williams, Benjamin, Swartz, Harold M, Hunt, Thomas K, Miclau, Theodore, Marcucio, Ralph S

“…Abstract Oxygen affects the activity of multiple skeletogenic cells and is involved in many processes that are important for fracture healing. However, the…”
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Transcutaneous oxygen measurement in humans using a paramagnetic skin adhesive film by Kmiec, Maciej M., Hou, Huagang, Lakshmi Kuppusamy, M., Drews, Thomas M., Prabhat, Anjali M., Petryakov, Sergey V., Demidenko, Eugene, Schaner, Philip E., Buckey, Jay C., Blank, Aharon, Kuppusamy, Periannan

“…Purpose Transcutaneous oxygen tension (TcpO2) provides information about blood perfusion in the tissue immediately below the skin. These data are valuable in…”
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Direct and Repeated Measurement of Heart and Brain Oxygenation Using In Vivo EPR Oximetry by Khan, Nadeem, Hou, Huagang, Swartz, Harold M, Kuppusamy, Periannan

“…Low level of oxygen (hypoxia) is a critical factor that defines the pathological consequence of several pathophysiologies, particularly ischemia, that usually…”
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Repetitive tissue pO2 measurements by electron paramagnetic resonance oximetry: current status and future potential for experimental and clinical studies by Khan, Nadeem, Williams, Benjamin B, Hou, Huagang, Li, Hongbin, Swartz, Harold M

“…Tissue oxygen plays a crucial role in maintaining tissue viability and in various diseases, including responses to therapy. Useful knowledge has been gained by…”
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Monitoring oxygen levels in orthotopic human glioma xenograft following carbogen inhalation and chemotherapy by implantable resonator‐based oximetry by Hou, Huagang, Krishnamurthy Nemani, Venkata, Du, Gaixin, Montano, Ryan, Song, Rui, Gimi, Barjor, Swartz, Harold M., Eastman, Alan, Khan, Nadeem

“…Hypoxia is a critical hallmark of glioma, and significantly compromises treatment efficacy. Unfortunately, techniques for monitoring glioma pO2 to facilitate…”
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First-In-Human Study in Cancer Patients Establishing the Feasibility of Oxygen Measurements in Tumors Using Electron Paramagnetic Resonance With the OxyChip by Schaner, Philip E, Williams, Benjamin B, Chen, Eunice Y, Pettus, Jason R, Schreiber, Wilson A, Kmiec, Maciej M, Jarvis, Lesley A, Pastel, David A, Zuurbier, Rebecca A, DiFlorio-Alexander, Roberta M, Paydarfar, Joseph A, Gosselin, Benoit J, Barth, Richard J, Rosenkranz, Kari M, Petryakov, Sergey V, Hou, Huagang, Tse, Dan, Pletnev, Alexandre, Flood, Ann Barry, Wood, Victoria A, Hebert, Kendra A, Mosher, Robyn E, Demidenko, Eugene, Swartz, Harold M, Kuppusamy, Periannan

“…The overall objective of this clinical study was to validate an implantable oxygen sensor, called the 'OxyChip', as a clinically feasible technology that would…”
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Real-time monitoring of ischemic and contralateral brain pO2 during stroke by variable length multisite resonators by Hou, Huagang, Li, Hongbin, Dong, Ruhong, Khan, Nadeem, Swartz, Harold

“…Abstract Purpose Electron paramagnetic resonance (EPR) oximetry using variable length multi-probe implantable resonator (IR), was used to investigate the…”
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Tissue pO2 of Orthotopic 9L and C6 Gliomas and Tumor-Specific Response to Radiotherapy and Hyperoxygenation by Khan, Nadeem, Ph.D, Li, Hongbin, Ph.D, Hou, Huagang, M.D, Lariviere, Jean P., B.S, Gladstone, David J., Sc.D, Demidenko, Eugene, Ph.D, Swartz, Harold M., M.D, Ph.D

“…Purpose Tumor hypoxia is a well-known therapeutic problem; however, a lack of methods for repeated measurements of glioma partial pressure of oxygen (pO2 )…”
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Mechanical Stability Affects Angiogenesis During Early Fracture Healing by Lu, Chuanyong, Saless, Neema, Hu, Diane, Wang, Xiaodong, Xing, Zhiqing, Hou, Huagang, Williams, Benjamin, Swartz, Harold M, Colnot, Celine, Miclau, Theodore, Marcucio, Ralph S

“…OBJECTIVES:The goal of this study was to determine to what extent mechanical stability affects vascular repair during fracture healing. METHODS:Stabilized and…”
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Repeated tumor pO2 measurements by multi-site EPR oximetry as a prognostic marker for enhanced therapeutic efficacy of fractionated radiotherapy by Hou, Huagang, Lariviere, Jean P, Demidenko, Eugene, Gladstone, David, Swartz, Harold, Khan, Nadeem

“…Abstract Purpose To investigate the temporal effects of single or fractionated radiotherapy on subcutaneous RIF-1 tumor pO2 and to determine the therapeutic…”
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Effect of Hyperoxygenation on Tissue pO2 and Its Effect on Radiotherapeutic Efficacy of Orthotopic F98 Gliomas by Khan, Nadeem, Ph.D, Mupparaju, Sriram, M.S, Hekmatyar, Shahryar K., Ph.D, Hou, Huagang, M.D, Lariviere, Jean P., B.A, Demidenko, Eugene, Ph.D, Gladstone, David J., Sc.D, Kauppinen, Risto A., M.D, Ph.D, Swartz, Harold M., M.D., Ph.D

“…Purpose Lack of methods for repeated assessment of tumor pO2 limits the ability to test and optimize hypoxia-modifying procedures being developed for clinical…”
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Effect of Hyperoxygenation on Tissue pO{sub 2} and Its Effect on Radiotherapeutic Efficacy of Orthotopic F98 Gliomas by Khan, Nadeem, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, Mupparaju, Sriram M.S., Hekmatyar, Shahryar K., Hou Huagang, Lariviere, Jean P., Demidenko, Eugene, Gladstone, David J., Kauppinen, Risto A., Swartz, Harold M.

“…Purpose: Lack of methods for repeated assessment of tumor pO{sub 2} limits the ability to test and optimize hypoxia-modifying procedures being developed for…”
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Repeated tumor oximetry to identify therapeutic window during metronomic cyclophosphamide treatment of 9L gliomas by MUPPARAJU, Sriram, HUAGANG HOU, LARIVIERE, Jean P, SWARTZ, Harold, JOUNAIDI, Youssef, KHAN, Nadeem

“…Malignant gliomas are aggressive and angiogenic tumors with high VEGF content. Consequently, approaches such as metronomic chemotherapy, which have an…”
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Seizure-induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension by Patel, Manisha, Liang, Li-Ping, Hou, Huagang, Williams, Benjamin B, Kmiec, Maciej, Swartz, Harold M, Fessel, Joshua P, Roberts, L. Jackson II

“…We have previously shown that seizures induce the formation of F₂-isoprostanes (F₂-IsoPs), one of the most reliable indices of oxidative stress in vivo…”
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Clinical applications of EPR: overview and perspectives by Swartz, Harold M., Khan, Nadeem, Buckey, Jay, Comi, Richard, Gould, Lisa, Grinberg, Oleg, Hartford, Alan, Hopf, Harriet, Hou, Huagang, Hug, Eugen, Iwasaki, Akinori, Lesniewski, Piotr, Salikhov, Ildar, Walczak, Tadeusz

“…The development and use of in vivo techniques for strictly experimental applications in animals has been very successful, and these results now have made…”
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Effect of a Topical Vasodilator on Tumor Hypoxia and Tumor Oxygen Guided Radiotherapy using EPR Oximetry by Hou, Huagang, Abramovic, Zrinka, Lariviere, Jean P., Sentjurc, Marjeta, Swartz, Harold, Khan, Nadeem

“…We sought to reduce tumor hypoxia by topical application of a vasodilator, benzyl nicotinate (BN), and investigated its effect on the growth of tumors…”
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Synergistic combination of hyperoxygenation and radiotherapy by repeated assessments of tumor pO2 with EPR oximetry by Hou, Huagang, Dong, Ruhong, Lariviere, Jean P, Mupparaju, Sriram P, Swartz, Harold M, Khan, Nadeem

“…The effect of hyperoxygenation with carbogen (95% O(2) + 5% CO(2)) inhalation on RIF-1 tumor pO(2 )and its consequence on growth inhibition with fractionated…”
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Clinical EPR by Swartz, Harold M., MD, PhD, MSPH, Williams, Benjamin B., PhD, Zaki, Bassem I., MD, Hartford, Alan C., MD, PhD, Jarvis, Lesley A., MD, PhD, Chen, Eunice Y., MD, PhD, Comi, Richard J., MD, Ernstoff, Marc S., MD, Hou, Huagang, MD, Khan, Nadeem, PhD, Swarts, Steven G., PhD, Flood, Ann B., PhD, Kuppusamy, Periannan, PhD

“…Electron paramagnetic resonance (EPR) spectroscopy has been well established as a viable technique for measurement of free radicals and oxygen in biological…”
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