Search Results - "Houštěk, J"

Nuclear genetic defects of mitochondrial ATP synthase by Hejzlarová, K, Mráček, T, Vrbacký, M, Kaplanová, V, Karbanová, V, Nůsková, H, Pecina, P, Houštěk, J

“…Disorders of ATP synthase, the key enzyme of mitochondrial energy provision belong to the most severe metabolic diseases presenting as early-onset…”
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Role of cytochrome c oxidase nuclear-encoded subunits in health and disease by Čunátová, K, Reguera, D P, Houštěk, J, Mráček, T, Pecina, P

“…Cytochrome c oxidase (COX), the terminal enzyme of mitochondrial electron transport chain, couples electron transport to oxygen with generation of proton…”
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Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity by Pravenec, M, Zídek, V, Landa, V, Mlejnek, P, Šilhavý, J, Šimáková, M, Trnovská, J, Škop, V, Marková, I, Malínská, H, Hüttl, M, Kazdová, L, Bardová, K, Tauchmannová, K, Vrbacký, M, Nůsková, H, Mráček, T, Kopecký, J, Houštěk, J

“…Brown adipose tissue (BAT) plays an important role in lipid and glucose metabolism in rodents and possibly also in humans. Identification of genes responsible…”
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Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat by Trnovská, J, Šilhavý, J, Zídek, V, Šimáková, M, Mlejnek, P, Landa, V, Eigner, S, Eigner Henke, K, Škop, V, Oliyarnyk, O, Kazdová, L, Mráček, T, Houštěk, J, Pravenec, M

“…Cold exposure of rats leads to ameliorated glucose and triglyceride utilization with females displaying better adaptation to a cold environment. In the current…”
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Deficiency of mitochondrial ATP synthase of nuclear genetic origin by Sperl, W., Ješina, P., Zeman, J., Mayr, J.A., DeMeirleir, L., VanCoster, R., Pícková, A., Hansíková, H., Houšt’ková, H., Krejčík, Z., Koch, J., Smet, J., Muss, W., Holme, E., Houštěk, J.

“…We present clinical and laboratory data from 14 cases with an isolated deficiency of the mitochondrial ATP synthase (7–30% of control) caused by nuclear…”
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Genetic defects of cytochrome c oxidase assembly by Pecina, P, Houstková, H, Hansíková, H, Zeman, J, Houstek, J

“…Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, is one of the key functional and regulatory sites of the mammalian…”
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Tert-butyl hydroperoxide selectively inhibits mitochondrial respiratory-chain enzymes in isolated rat hepatocytes by Drahota, Z, Kriváková, P, Cervinková, Z, Kmonícková, E, Lotková, H, Kucera, O, Houstek, J

“…Sensitivity of various mitochondrial enzymes to oxidative damage was tested on isolated rat liver hepatocytes permeabilized by digitonin. In permeabilized…”
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Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells by Hermanova, I, Arruabarrena-Aristorena, A, Valis, K, Nuskova, H, Alberich-Jorda, M, Fiser, K, Fernandez-Ruiz, S, Kavan, D, Pecinova, A, Niso-Santano, M, Zaliova, M, Novak, P, Houstek, J, Mracek, T, Kroemer, G, Carracedo, A, Trka, J, Starkova, J

“…l -asparaginase (ASNase), a key component in the treatment of childhood acute lymphoblastic leukemia (ALL), hydrolyzes plasma asparagine and glutamine and…”
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Activities of cytochrome c oxidase and citrate synthase in lymphocytes of obese and normal-weight subjects by Čapková, M, Houštěk, J, Hansikovǎ, H, Hainer, V, Kunešová, M, Zeman, J

“…BACKGROUND: Obesity represents a heterogeneous group of disorders associated with broad spectrum of metabolic and endocrine abnormalities. The metabolic…”
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Time-course of hormonal induction of mitochondrial glycerophosphate dehydrogenase biogenesis in rat liver by Mráček, T., Ješina, P., Křiváková, P., Bolehovská, R., Červinková, Z., Drahota, Z., Houštěk, J.

“…Thyroid hormones are important regulators of mitochondrial metabolism. Due to their complex mechanism of action, the timescale of different responses varies…”
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Developmental changes of cytochrome c oxidase and citrate synthase in rat heart homogenate by Drahota, Z, Milerová, M, Stieglerová, A, Houstek, J, Ostádal, B

“…Activity of cytochrome c oxidase and citrate synthase in rat heart homogenates was determined in 5-, 15-, 28- and 60-day-old rats. The activity of both enzymes…”
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Activities of mitochondrial oxidative phosphorylation enzymes in cultured amniocytes by Chowdhury, S.K.R, Drahota, Z, Floryk, D, Calda, P, Houštěk, J

“…Amniocytes represent a population of foetal cells that can be used for prenatal diagnosis in families with suspected mitochondrial oxidative phosphorylation…”
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Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat by FLACHS, P, HORAKOVA, O, KEIJER, J, HOUSTEK, J, KOPECKY, J, BRAUNER, P, ROSSMEISL, M, PECINA, P, FRANSSEN-VAN HAL, N, RUZICKOVA, J, SPONAROVA, J, DRAHOTA, Z, VLCEK, C

“…Intake of n-3 polyunsaturated fatty acids reduces adipose tissue mass, preferentially in the abdomen. The more pronounced effect of marine-derived…”
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Specific Properties of Heavy Fraction of Mitochondria from Human-term Placenta – Glycerophosphate-dependent Hydrogen Peroxide Production by Honzík, T., Drahota, Z., Böhm, M., Ješina, P., Mrácˇek, T., Paul, J., Zeman, J., Houštěk, J.

“…Mitochondrial respiratory chain enzyme Complexes are present in placenta at proportion similar to other tissues with exception of glycerophosphate…”
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Polarographic evaluation of mitochondrial enzymes activity in isolated mitochondria and in permeabilized human muscle cells with inherited mitochondrial defects by Wenchich, L, Drahota, Z, Honzík, T, Hansíková, H, Tesarová, M, Zeman, J, Houstek, J

“…Inherited disturbances of the mitochondrial energy generating system represent a heterogeneous group of disorders associated with a broad spectrum of metabolic…”
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Glycerophosphate-dependent hydrogen peroxide production by rat liver mitochondria by Jesina, P, Kholová, D, Bolehovská, R, Cervinková, Z, Drahota, Z, Houstek, J

“…We studied the extent to which hormonally-induced mitochondrial glycerophosphate dehydrogenase (mGPDH) activity contributes to the supply of reducing…”
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Czech Footprints in the Bioenergetics Research by Drahota, Z, Houštěk, J, Pecinová, A

“…Life manifests as growth, movement or heat production that occurs thanks to the energy accepted from the outside environment. The basis of energy transduction…”
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Variability of Clinical Phenotypes Caused by Isolated Defects of Mitochondrial ATP Synthase by Tauchmanová, K, Pecinová, A, Houštěk, J, Mráček, T

“…Disorders of ATP synthase, the key enzyme in mitochondrial energy supply, belong to the most severe metabolic diseases, manifesting as early-onset…”
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Optimal conditions for determination of cytochrome c oxidase activity in the rat heart by Stieglerová, A, Drahota, Z, Ostádal, B, Houstek, J

“…The determination of cytochrome c oxidase (COX) activity represents an important indicator for the evaluation of cell oxidative capacity. However, it has been…”
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The Effect of Diabetes Mellitus on Cardiac Mitochondria in Patients With End-Stage Heart Failure by Melenovsky, V, Benes, J, Pirk, J, Pelikanova, T, Mracek, T, Nuskova, H, Drahota, Z, Kovalcikova, J, Houstek, J

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