Search Results - "Hou, Zhenlin"

M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer by Lan, Jingqin, Sun, Li, Xu, Feng, Liu, Lu, Hu, Fuqing, Song, Da, Hou, Zhenlin, Wu, Wei, Luo, Xuelai, Wang, Jing, Yuan, Xianglin, Hu, Junbo, Wang, Guihua

“…: Clinical and experimental evidence has shown that tumor-associated macrophages promote cancer initiation and progression. However, the macrophage-derived…”
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TRIM25 regulates oxaliplatin resistance in colorectal cancer by promoting EZH2 stability by Zhou, Sha, Peng, Jianhong, Xiao, Liuniu, Zhou, Caixia, Fang, Yujing, Ou, Qingjian, Qin, Jiayi, Liu, Mengzhong, Pan, Zhizhong, Hou, Zhenlin

“…Resistance to chemotherapy remains the major cause of treatment failure in patients with colorectal cancer (CRC). Here, we identified TRIM25 as an epigenetic…”
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SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis by Wang, Guihua, Long, Jie, Gao, Yuan, Zhang, Weina, Han, Fei, Xu, Chuan, Sun, Li, Yang, Shun-Chin, Lan, Jingqin, Hou, Zhenlin, Cai, Zhen, Jin, Guoxiang, Hsu, Che-Chia, Wang, Yu-Hui, Hu, Junbo, Chen, Tsai-Yu, Li, Hongyu, Lee, Min Gyu, Lin, Hui-Kuan

“…The serine/threonine kinase Akt plays a central role in cell proliferation, survival and metabolism, and its hyperactivation is linked to cancer progression…”
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Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer by Sui, Qiaoqi, Zhang, Xi, Chen, Chao, Tang, Jinghua, Yu, Jiehai, Li, Weihao, Han, Kai, Jiang, Wu, Liao, Leen, Kong, Lingheng, Li, Yuan, Hou, Zhenlin, Zhou, Chi, Zhang, Chenzhi, Zhang, Linjie, Xiao, Binyi, Mei, Weijian, Xu, Yanbo, Qin, Jiayi, Zheng, Jian, Pan, Zhizhong, Ding, Pei-Rong

“…Inflammation is a common medical complication in colorectal cancer (CRC) patients, which plays significant roles in tumor progression and immunosuppression…”
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TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling by Hou, Zhenlin, Guo, Kaixuan, Sun, Xuling, Hu, Fuqing, Chen, Qianzhi, Luo, Xuelai, Wang, Guihua, Hu, Junbo, Sun, Li

“…Cellular senescence is a state of irreversible cell growth arrest and senescence cells permanently lose proliferation potential. Induction of cellular…”
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The autophagy-independent role of BECN1 in colorectal cancer metastasis through regulating STAT3 signaling pathway activation by Hu, Fuqing, Li, Geng, Huang, Changsheng, Hou, Zhenlin, Yang, Xi, Luo, Xuelai, Feng, Yongdong, Wang, Guihua, Hu, Junbo, Cao, Zhixin

“…BECN1 is a critical regulator of autophagy, which plays important roles in tumor formation and metastasis. However, the autophagy-independent role of BECN1 and…”
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A log odds of positive lymph nodes-based predictive model effectively forecasts prognosis and guides postoperative adjuvant chemotherapy duration in stage III colon cancer: a multi-center retrospective cohort study by Zhang, Weili, Hou, Zhenlin, Zhang, Linjie, Hong, Xuanlin, Wang, Weifeng, Wu, Xiaojun, Xu, Dongbo, Lu, Zhenhai, Chen, Jianxun, Peng, Jianhong

“…The log odds of positive lymph nodes (LODDS) was considered a superior staging system to N stage in colon cancer, yet its value in determining the optimal…”
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The effects of oxaliplatin-based adjuvant chemotherapy in high-risk stage II colon cancer with mismatch repair-deficient: a retrospective study by Liao, Leen, Tang, Jinghua, Hong, Zhigang, Jiang, Wu, Li, Yuan, Kong, Lingheng, Han, Kai, Hou, Zhenlin, Zhang, Chenzhi, Zhou, Chi, Zhang, Linjie, Sui, Qiaoqi, Xiao, Binyi, Mei, Weijian, Yu, Jiehai, Yang, Wanjun, Pan, Zhizhong, Ding, Pei-Rong

“…For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study…”
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Native amine-directed site-selective C(sp3)-H arylation of primary aliphatic amines with aryl iodides by Pramanick, Pranab K., Zhou, Zhibing, Hou, Zhenlin, Ao, Yufei, Yao, Bo

“…The first NH2-directed γ-C(sp3)-H arylation of primary aliphatic amines with aryl iodides was developed. [Display omitted] Direct C(sp3)-H functionalization of…”
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Author Correction: SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis by Wang, Guihua, Long, Jie, Gao, Yuan, Zhang, Weina, Han, Fei, Xu, Chuan, Sun, Li, Yang, Shun-Chin, Lan, Jingqin, Hou, Zhenlin, Cai, Zhen, Jin, Guoxiang, Hsu, Che-Chia, Wang, Yu-Hui, Hu, Junbo, Chen, Tsai-Yu, Li, Hongyu, Lee, Min Gyu, Lin, Hui-Kuan

“…A Correction to this paper has been published: https://doi.org/10.1038/s41556-021-00686-x…”
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Conversion therapy with the intent to perform radical local treatment may not be suitable for patients with 10 or more liver metastases from colorectal cancer by Lin, Junzhong, Sun, Hui, Zhang, Weili, Hong, Zhigang, Lu, Zhenhai, Pan, Zhizhong, Hou, Zhenlin, Peng, Jianhong

“…Background The number of colorectal cancer liver metastases (CRLMs) is usually considered a contradictory indicator to surgical resection. However, some…”
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Active Modulation of an All-Dielectric Metasurface Analogue of Electromagnetically Induced Transparency in Terahertz by Wang, Luyao, Gao, Zijie, Hou, Zhenlin, Song, Jinmei, Liu, Xiaoyu, Zhang, Yifei, Wang, Xiaodong, Yang, Fuhua, Shi, Yanpeng

“…In this work, an analogue of electromagnetically induced transparency (EIT) is excited by a periodic unit consisting of a silicon rectangular bar resonator and…”
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SETDB1-mediated methylation of Akt promotes itsK63-linked ubiquitination and activation leading totumorigenesis by Wang, Guihua, Long, Jie, Gao, Yuan, Zhang, Weina, Han, Fei, Xu, Chuan, Sun, Li, Shun-Chin, Yang, Lan Jingqin, Hou Zhenlin, Cai Zhen, Jin Guoxiang, Che-Chia, Hsu, Yu-Hui, Wang, Hu Junbo, Tsai-Yu, Chen, Li, Hongyu, Lee, Min Gyu, Hui-Kuan, Lin

“…The serine/threonine kinase Akt plays a central role in cell proliferation, survival and metabolism, and its hyperactivation is linked to cancer progression…”
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RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2 by Chen, Yaqi, Zhou, Sha, Wan, Kairui, Yu, Long, Zhao, Chongchong, Deng, Haiteng, Ou, Qingjian, Qin, Jiayi, Hu, Junbo, Hou, Zhenlin

“…RIO Kinase 1 (RIOK1) is involved in various pathologies, including cancer. However, the role of RIOK1 in radioresistance of colorectal cancer (CRC) remains…”
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Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer by Li, Weihao, Zhou, Chi, Yu, Long, Hou, Zhenlin, Liu, Huashan, Kong, Lingheng, Xu, Yanbo, He, Jiahua, Lan, Jin, Ou, Qingjian, Fang, Yujing, Lu, Zhenhai, Wu, Xiaojun, Pan, Zhizhong, Peng, Jianhong, Lin, Junzhong

“…Bevacizumab plays an important role in the first and second line treatment for metastatic colorectal cancer (CRC). And induction of hypoxia and the tumors…”
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PACE: A phase III trial of CAPOX versus anti-PD-1 inhibitor as adjuvant therapy for patients with dMMR/MSI-H stage III colon cancer by Hou, Zhenlin, Jiang, Wu, Tang, Jinghua, Xiao, Binyi, Li, Yuan, Li, Dandan, Zhang, Xiaoshi, Pan, Zhi-Zhong, Ding, Peirong

“…TPS3637 Background: Approximately 12% of stage III colon cancer are deficient mismatch repair (dMMR), leading to high levels of microsatellite instability…”
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SIX4 activates Akt and promotes tumor angiogenesis by Sun, Xuling, Hu, Fuqing, Hou, Zhenlin, Chen, Qianzhi, Lan, Jingqin, Luo, Xuelai, Wang, Guihua, Hu, Junbo, Cao, Zhixin

“…Angiogenesis plays important roles in solid tumors progression. Growth factors such as vascular endothelial growth factors (VEGFs) can induce angiogenesis and…”
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Blocking histone methyltransferase SETDB1 inhibits tumorigenesis and enhances cetuximab sensitivity in colorectal cancer by Hou, Zhenlin, Sun, Li, Xu, Feng, Hu, Fuqing, Lan, Jingqin, Song, Da, Feng, Yongdong, Wang, Jing, Luo, Xuelai, Hu, Junbo, Wang, Guihua

“…The histone methyltransferase SETDB1 catalyzes the addition of methyl groups to histone H3 at lysine 9, and upregulation of SETDB1 is associated with poor…”
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Cloning and functional characterization of a tau class glutathione transferase associated with haloxyfop‐P‐methyl resistance in Digitaria sanguinalis by Liu, Xiangying, Hou, Zhenlin, Zhang, Yuying, Merchant, Austin, Zhong, Mei‐e, Ma, Guolan, Zeng, Qing, Wu, Lamei, Zhou, Xuguo, Luo, Kun, Ding, Chunxia

“…Background Haloxyfop‐P‐methyl, an acetyl‐CoA carboxylase (ACCase)‐inhibiting herbicide, has been extensively used to control grass weeds. Widespread use of…”
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B2M and JAK1/2–mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy by Zhang, Chenzhi, Li, Dandan, Xiao, Binyi, Zhou, Chi, Jiang, Wu, Tang, Jinghua, Li, Yuan, Zhang, Rongxin, Han, Kai, Hou, Zhenlin, Zhang, Linjie, Sui, Qiaoqi, Liao, Leen, Pan, Zhizhong, Zhang, Xiaoshi, Ding, Peirong

“…β2-microglobulin (B2M) and Janus kinases 1 and 2 (JAK1/2) mutations have been suggested as genetic mechanisms of immune evasion for anti–programmed cell death…”
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